PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_D11G0976

Common Name

WRKY48, WRKY88

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

WRKY

Protein Properties

Length: 335aa MW: 35926.7 Da PI: 5.8695

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_D11G0976	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	98.4	4.6e-31	155	213	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 +D ++WrKYGqK++kgs++pr+YYrC+++ gC ++k+vers++dp ++++tY+ eHnh+ Gh_D11G0976 155 SDVWAWRKYGQKPIKGSPYPRGYYRCSTSkGCLARKQVERSRTDPAMFIVTYTAEHNHP 213 79**********************9988**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	4.7E-31	144	215	IPR003657	WRKY domain
PROSITE profile	PS50811	34.888	149	215	IPR003657	WRKY domain
SuperFamily	SSF118290	1.7E-26	150	215	IPR003657	WRKY domain
SMART	SM00774	2.6E-37	154	214	IPR003657	WRKY domain
Pfam	PF03106	7.4E-26	156	213	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010150	Biological Process	leaf senescence
GO:0010200	Biological Process	response to chitin
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 335 aa Download sequence Send to blast
MEVDWDLHAV VRGCATVTAT GNGGVGSGYS MADLLPPQSG VSSFGSEEAF EGHALSSPNQ 60 LEELHELYKP FFPKSQPLSP QSTPLSSLSS ISFSKEARIE EQQQQSKLSL AASVTTAITA 120 PTNNSATSTS HNSRSKRRKN QLKKVCQVPT EGISSDVWAW RKYGQKPIKG SPYPRGYYRC 180 STSKGCLARK QVERSRTDPA MFIVTYTAEH NHPAPTHHNS LAGSTRQKPC TSQTPTAGDS 240 VKPFSAKPAG SSSLTTSVDE ELMVQNTKAG SREDLVEDEG EDDFGMSDTA VSDDFFEGLE 300 GIADMVTGNC FSDRFQPSCD LPWIASNAAT AAGGV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5w3x_B	1e-22	139	216	2	80	Disease resistance protein RRS1
5w3x_D	1e-22	139	216	2	80	Disease resistance protein RRS1
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the expression of defense genes in innate immune response of plants. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Activates WRKY 29, SIRK and its own promoters. {ECO:0000269\|PubMed:11875555}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00422	DAP	Transfer from AT4G01250	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced after flagellin treatment. {ECO:0000269\|PubMed:11875555}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KF031110	0.0	KF031110.1 Gossypium hirsutum WRKY transcription factor 88 (WRKY88) mRNA, complete cds.
GenBank	KF669785	0.0	KF669785.1 Gossypium hirsutum WRKY transcription factor 48 (WRKY48) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001313974.1	0.0	WRKY transcription factor 22-like
Swissprot	O04609	4e-91	WRK22_ARATH; WRKY transcription factor 22
TrEMBL	A0A059Q7B6	0.0	A0A059Q7B6_GOSHI; WRKY transcription factor 22-like
STRING	Gorai.007G103400.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM7810	27	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G01250.1	3e-75	WRKY family protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Coego A, et al. The TRANSPLANTA collection of Arabidopsis lines: a resource for functional analysis of transcription factors based on their conditional overexpression. Plant J., 2014. 77(6): p. 944-53 [PMID:24456507] Dou L, et al. Genome-wide analysis of the WRKY gene family in cotton. Mol. Genet. Genomics, 2014. 289(6): p. 1103-21 [PMID:24942461] Gkizi D, et al. The Innate Immune Signaling System as a Regulator of Disease Resistance and Induced Systemic Resistance Activity Against Verticillium dahliae. Mol. Plant Microbe Interact., 2016. 29(4): p. 313-23 [PMID:26780421] Kloth KJ, et al. AtWRKY22 promotes susceptibility to aphids and modulates salicylic acid and jasmonic acid signalling. J. Exp. Bot., 2016. 67(11): p. 3383-96 [PMID:27107291] Camborde L, et al. Detection of nucleic acid-protein interactions in plant leaves using fluorescence lifetime imaging microscopy. Nat Protoc, 2017. 12(9): p. 1933-1950 [PMID:28837131] Wang S, et al. Bacillus cereus AR156 Activates Defense Responses to Pseudomonas syringae pv. tomato in Arabidopsis thaliana Similarly to flg22. Mol. Plant Microbe Interact., 2018. 31(3): p. 311-322 [PMID:29090631]