PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_A12G1594

Common Name

WRKY68

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

WRKY

Protein Properties

Length: 614aa MW: 66242.2 Da PI: 6.5178

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_A12G1594	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.3	4.2e-30	277	336	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+aed +v+++tYeg+Hnh+ Gh_A12G1594 277 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApSCPVRKQVQRCAEDLSVLITTYEGTHNHP 336 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	4.6E-32	262	338	IPR003657	WRKY domain
SuperFamily	SSF118290	2.09E-27	269	338	IPR003657	WRKY domain
PROSITE profile	PS50811	28.403	272	338	IPR003657	WRKY domain
SMART	SM00774	4.2E-36	277	337	IPR003657	WRKY domain
Pfam	PF03106	1.1E-26	278	336	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 614 aa Download sequence Send to blast
MEENLKKSSD DIGGGAVVKK EKIADSCADD EDAPAVVVVP KGGDKRPCCE NDDNKPSSPG 60 KKDLSSSNNN KVSLKSDTER TEPEYSMASS STRKVQDDQL ESAKAEMGEV REENQRLKMY 120 LNRIMKDYQK LQMQFYDIVG QDSKKSQPAE NNDRHHQQQE EEEPELVSLT LGRFSSDSKK 180 DGKNKASSSH GKEEERGNEG LSLGLDYKLE ASKSEVDDEA LPNPSPVNST QELKEEETWP 240 PSKVLKTTRT GDDEVLQQNP VKKPRVCVRT RCETPTMNDG CQWRKYGQKI AKGNPCPRAY 300 YRCTVAPSCP VRKQVQRCAE DLSVLITTYE GTHNHPLPMS ATAMASTTCA AASMLLSGAS 360 SSGSNVASLT STANLHGLNV YLTDNSKSKF YLPNSSLSAA LSHPTITLDL TSTPSSSSSF 420 PFNRFSSAYP TTSRYASTSL SFGSSESNTV SWGNGLLSYG SPSTQPYMKN PLNINGRPQS 480 TMENNSIFPS FMQKNNLNPP QQPLPDTIAA ATKAITTDPN FQSALAAALT SIIGTGNNNN 540 GGGGSGESLA QRLKWGEQTF AVNGNGCGSS FFNKPPPSTT SQPGSLIFLP PNSLPFSTPK 600 SASTSPGDTG NHTN

Sequence ? help Back to Top

Protein Sequence Length: 614 aa Download sequence Send to blast

MEENLKKSSD DIGGGAVVKK EKIADSCADD EDAPAVVVVP KGGDKRPCCE NDDNKPSSPG  60
KKDLSSSNNN KVSLKSDTER TEPEYSMASS STRKVQDDQL ESAKAEMGEV REENQRLKMY  120
LNRIMKDYQK LQMQFYDIVG QDSKKSQPAE NNDRHHQQQE EEEPELVSLT LGRFSSDSKK  180
DGKNKASSSH GKEEERGNEG LSLGLDYKLE ASKSEVDDEA LPNPSPVNST QELKEEETWP  240
PSKVLKTTRT GDDEVLQQNP VKKPRVCVRT RCETPTMNDG CQWRKYGQKI AKGNPCPRAY  300
YRCTVAPSCP VRKQVQRCAE DLSVLITTYE GTHNHPLPMS ATAMASTTCA AASMLLSGAS  360
SSGSNVASLT STANLHGLNV YLTDNSKSKF YLPNSSLSAA LSHPTITLDL TSTPSSSSSF  420
PFNRFSSAYP TTSRYASTSL SFGSSESNTV SWGNGLLSYG SPSTQPYMKN PLNINGRPQS  480
TMENNSIFPS FMQKNNLNPP QQPLPDTIAA ATKAITTDPN FQSALAAALT SIIGTGNNNN  540
GGGGSGESLA QRLKWGEQTF AVNGNGCGSS FFNKPPPSTT SQPGSLIFLP PNSLPFSTPK  600
SASTSPGDTG NHTN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	2e-22	268	338	8	77	Probable WRKY transcription factor 4
2lex_A	2e-22	268	338	8	77	Probable WRKY transcription factor 4
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, trichomes and fruits. {ECO:0000269\|PubMed:24884371}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KF669826	0.0	KF669826.1 Gossypium hirsutum WRKY transcription factor 68 (WRKY68) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017621370.1	0.0	PREDICTED: probable WRKY transcription factor 61 isoform X1
Swissprot	A0A3Q7GFB5	1e-127	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A1U8NBE7	0.0	A0A1U8NBE7_GOSHI; probable WRKY transcription factor 61 isoform X1
STRING	Gorai.008G191200.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2959	28	68

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G18860.1	2e-68	WRKY DNA-binding protein 61

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371] Dou L, et al. Genome-wide analysis of the WRKY gene family in cotton. Mol. Genet. Genomics, 2014. 289(6): p. 1103-21 [PMID:24942461]