PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_A12G0994
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family ERF
Protein Properties Length: 157aa    MW: 17635.8 Da    PI: 9.9891
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_A12G0994genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP266.55.4e-2168117255
          AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                  +y+GVr+++ +grW+AeIrdp++   r+r++lg+++taeeAa  +++a+ +++g
  Gh_A12G0994  68 KYRGVRRRP-WGRWAAEIRDPTS---RTRVWLGTYDTAEEAALVYDRAAIRIKG 117
                  8********.**********965...4***********************9988 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0381231.9E-401157IPR017392AP2/ERF transcription factor ERF/PTI6
Gene3DG3DSA:3.30.730.101.3E-3068125IPR001471AP2/ERF domain
SuperFamilySSF541713.53E-2268124IPR016177DNA-binding domain
PfamPF008471.0E-1468117IPR001471AP2/ERF domain
SMARTSM003801.6E-3668131IPR001471AP2/ERF domain
PROSITE profilePS5103223.76268125IPR001471AP2/ERF domain
CDDcd000185.90E-3368124No hitNo description
PRINTSPR003673.0E-116980IPR001471AP2/ERF domain
PRINTSPR003673.0E-1191107IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 157 aa     Download sequence    Send to blast
MESNAKASRI IKVCITDGDA TDSSSSEKPE HRRAKRNING IRVEDCKSNL SSMRSKKQQQ  60
QCLSNGVKYR GVRRRPWGRW AAEIRDPTSR TRVWLGTYDT AEEAALVYDR AAIRIKGPNA  120
LTNFVKPPST SEIELETIFE YNSSQESQAL SSPTSVL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A2e-2264124162ATERF1
3gcc_A2e-2264124162ATERF1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtComponent of the cytokinin signaling pathway involved in cotyledons, leaves, and embryos development. Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269|PubMed:16832061}.
UniProtComponent of the cytokinin signaling pathway involved in cotyledons, leaves, and embryos development. Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269|PubMed:16832061}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By cytokinins. {ECO:0000269|PubMed:16832061}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017635532.11e-108PREDICTED: ethylene-responsive transcription factor CRF6-like
SwissprotO823398e-41CRF5_ARATH; Ethylene-responsive transcription factor CRF5
SwissprotQ9SUE32e-40CRF4_ARATH; Ethylene-responsive transcription factor CRF4
TrEMBLA0A1U8NFH71e-99A0A1U8NFH7_GOSHI; ethylene-responsive transcription factor CRF6-like
STRINGGorai.008G123400.11e-95(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM25782571
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G46310.13e-43cytokinin response factor 5
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Zwack PJ,Compton MA,Adams CI,Rashotte AM
    Cytokinin response factor 4 (CRF4) is induced by cold and involved in freezing tolerance.
    Plant Cell Rep., 2016. 35(3): p. 573-84
    [PMID:26650835]
  4. Raines T, et al.
    The cytokinin response factors modulate root and shoot growth and promote leaf senescence in Arabidopsis.
    Plant J., 2016. 85(1): p. 134-47
    [PMID:26662515]
  5. Striberny B, et al.
    Cytokinin Response Factor 5 has transcriptional activity governed by its C-terminal domain.
    Plant Signal Behav, 2017. 12(2): p. e1276684
    [PMID:28045578]