PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Cotton_A_07316_BGI-A2_v1.0 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
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Family | bHLH | ||||||||
Protein Properties | Length: 658aa MW: 71420.5 Da PI: 5.3545 | ||||||||
Description | bHLH family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | HLH | 39.3 | 1.2e-12 | 482 | 527 | 4 | 54 |
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h e+Er+RR+++N++f Lr ++P+ K++Ka+ L A+ YI++L Cotton_A_07316_BGI-A2_v1.0 482 NHVEAERQRREKLNQKFYALRAVVPNV-----SKMDKASLLGDAISYINEL 527 799***********************6.....5***************998 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Pfam | PF14215 | 1.0E-57 | 81 | 262 | IPR025610 | Transcription factor MYC/MYB N-terminal |
PROSITE profile | PS50888 | 17.25 | 478 | 527 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SuperFamily | SSF47459 | 9.81E-19 | 481 | 552 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
CDD | cd00083 | 8.20E-15 | 481 | 532 | No hit | No description |
Gene3D | G3DSA:4.10.280.10 | 7.4E-19 | 482 | 548 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam | PF00010 | 3.8E-10 | 482 | 527 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SMART | SM00353 | 9.2E-17 | 484 | 533 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 658 aa Download sequence Send to blast |
MKDYRLAPTM NLWTDDNAPV MEAFMSSDLS SLWPPPLSSA STSTPAASAA GGGGGGGGHD 60 LSISFLAQSQ PSVSLLNQET LQQRLQALIE GGRDCWTYAI FWQSSYDYSG ATVLGWGDGY 120 YKGEEDKGKG KSKAYSSSVA EQEHRKKVLR ELNSLISGST ATADDAVDEE VTDTEWFFLV 180 SMTQSFVTGS GLPGQALYNS SPVWVAGSGR LASSMCERAR QGQLFGLQTI VCIPSANGVV 240 ELGSTELITQ SSDLMNKVRI LFNFNNGIEA GSWSVSNNTA DQGENDPSSL WISEPNNGVE 300 PKDNNNNGNH NPSIQDPSTS SLTENPSSIH GGNQQQQPQG QSFRLNFSDY GFDGNSSVKN 360 GKFSAHLLKP ESGEILNFGE SKKSGNGNLF SANSQLVVEE NKKKRSPTSR GSNEDGMISF 420 TSGAVLPCSG VAKPGGCARD SDNSDIEASI VKEADSSRVV EPEKRPRKRG RKPANGREEP 480 LNHVEAERQR REKLNQKFYA LRAVVPNVSK MDKASLLGDA ISYINELRTK VQDADSEKEE 540 LLKQLDEMKK QLASKESCSM APPPPDQDRN MSNKLIELDI DVKIIGLDAM IRIQCSKKNH 600 PAARLMTALK ELDLDVHHAS VSVVNDLMIQ QASVKMGSRF YTQEQLRIAL ASKVGDAR |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4rqw_A | 2e-76 | 76 | 265 | 4 | 195 | Transcription factor MYC3 |
4rqw_B | 2e-76 | 76 | 265 | 4 | 195 | Transcription factor MYC3 |
4rs9_A | 2e-76 | 76 | 265 | 4 | 195 | Transcription factor MYC3 |
4yz6_A | 2e-76 | 76 | 265 | 4 | 195 | Transcription factor MYC3 |
Search in ModeBase |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 463 | 471 | KRPRKRGRK |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcriptional activator that binds to the G-box motif (5'-AACGTG-3') found in the promoter of the jasmonate-induced gene LAPA1 (PubMed:15231736). Acts as negative regulator of blue light-mediated photomorphogenesis and positively regulates root growth (PubMed:24483714). Promotes growth in response to the phytohormones abscisic acid (ABA) and jasmonate (JA) (PubMed:24483714). Binds to the G-box motif (5'-CACGTG-3') of the RBCS-3A gene promoter (PubMed:24483714). Acts downstream of the jasmonate (JA) receptor to orchestrate JA-mediated activation of plant responses (PubMed:28733419). Positively regulates both wound-responsive and pathogen-responsive genes through MYC2-targeted transcription factors (MTFs) involved in early response to JA (PubMed:28733419). With JA2L forms a transcription module that regulates wounding-responsive genes (PubMed:28733419). With ERF.C3 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). Plays a critical role in orchestrating JA-mediated defense gene expression during Botrytis cinerea infection (PubMed:28733419). Regulates negatively defense responses to root-knot nematodes, potentially by mediating crosstalk among the hormones strigolactones, abscisic acid (ABA) and jasmonate (JA) (PubMed:30576511). Regulates the termination of JA-mediated defense responses by specifically binding the G-box (5'-CACATG-3') motifs in the promoters of MTB1, MTB2 and MTB3, which are transcription factors that negatively regulates JA signaling (PubMed:30610166). May be involved in JA-induced chilling tolerance, possibly by ameliorating the antioxidant enzyme system of fruit and increasing proline and lycopene levels (PubMed:29528226). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:24483714, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:29528226, ECO:0000269|PubMed:30576511, ECO:0000269|PubMed:30610166}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Induced by methyl jasmonate (PubMed:15231736, PubMed:28733419). Induced by wounding (PubMed:15231736). Induced by infection with the fungal pathogen Botrytis cinerea (PubMed:28733419). Induced in fruit by storage in cold (PubMed:29528226). Induced by hydrogen peroxide and infection with root-knot nematodes (PubMed:30576511). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:29528226, ECO:0000269|PubMed:30576511}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_017608416.1 | 0.0 | PREDICTED: transcription factor MYC4-like | ||||
Swissprot | A0A3Q7HRZ6 | 0.0 | MYC2_SOLLC; Transcription factor MYC2 | ||||
TrEMBL | A0A0D2QEJ8 | 0.0 | A0A0D2QEJ8_GOSRA; Uncharacterized protein | ||||
TrEMBL | A0A288F5E3 | 0.0 | A0A288F5E3_GOSHI; MYC transcription factor 1 | ||||
STRING | Gorai.006G216700.1 | 0.0 | (Gossypium raimondii) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM1265 | 28 | 96 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT1G32640.1 | 0.0 | bHLH family protein |