PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID FANhyb_rscf00000380.1.g00006.1
Organism
Fragaria x ananassa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae; Fragaria
Family E2F/DP
Protein Properties Length: 300aa    MW: 32607 Da    PI: 9.4902
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
FANhyb_rscf00000380.1.g00006.1genomekazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP68.39.5e-222491171
                         E2F_TDP  1 rkeksLrlltqkflklleksee..givtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                                    rk+ksL ll+++fl+l+++ +     + l+++a++L    v   rRRiYDi+NVLe+++l+++k+kn ++wkg
  FANhyb_rscf00000380.1.g00006.1 24 RKQKSLSLLCSNFLSLYNRDDGatVLIGLDDAASRL---GV--VRRRIYDIVNVLESVGLLSRKSKNTYTWKG 91
                                    79****************9766456789********...99..9***************************98 PP
2E2F_TDP43.45.4e-141261802971
                         E2F_TDP  29 evakeLvse.......dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                                     e+ak L+          +++k+RRiYDi+NVL+++nliek     + k+++rw g
  FANhyb_rscf00000380.1.g00006.1 126 EAAKLLLGVgdaqnvfVMRTKVRRIYDIANVLSSVNLIEKthtadTGKPAYRWLG 180
                                     5666665446677777899************************999*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.109.6E-242092IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.0E-262491IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023197.1E-202591IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.04E-142692IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.6E-6102180IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.4E-12126180IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.77E-9138181IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.4E-13144182IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 300 aa     Download sequence    Send to blast
MASSAAVDYP PATTTTRRDT SYSRKQKSLS LLCSNFLSLY NRDDGATVLI GLDDAASRLG  60
VVRRRIYDIV NVLESVGLLS RKSKNTYTWK GFAAVPDALK ELQEEGLDLT PIPAPRIGIE  120
SNFADEAAKL LLGVGDAQNV FVMRTKVRRI YDIANVLSSV NLIEKTHTAD TGKPAYRWLG  180
LNRRREGLDL NSEQGKKRSF GTDLTNVSCK KSKVAEKAMR NQGQAEKCNS DGGGAKESAK  240
SYQFGPFTPV VVPRGRKGVN INKVCWETGS LLPAAVPEPS DEGAVFTLQG SVEVVELSSC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A4e-15231743132Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011460987.11e-177PREDICTED: E2F transcription factor-like E2FE
SwissprotQ8RWL02e-59E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLA0A2P6QBP71e-141A0A2P6QBP7_ROSCH; Putative transcription factor E2F-DP family
STRINGGLYMA06G19843.12e-66(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.11e-52DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]