PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 462914484
Organism
Eragrostis tef
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Eragrostideae; Eragrostidinae; Eragrostis
Family NAC
Protein Properties Length: 405aa    MW: 46117.3 Da    PI: 5.6975
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
462914484genomeTefView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM72.61e-22880167
        NAM  1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk....kvka.....eekewyfFskrdkk 67
               +ppGfrFhPt+eelv +yL++kv+++k++l ++i+evd+y++ePwdL++             +++ewyfFs +d+k
  462914484  8 VPPGFRFHPTEEELVGYYLARKVASQKIDL-DIIQEVDLYRIEPWDLQErckqG--VtggeeQTTEWYFFSYKDRK 80
               69****************************.99**************9635551..044433555******99986 PP
2NAM151.92.9e-47802336128
        NAM   6 rFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk.........................kvkaeekewyfFskrdkkyatgkrknratks 80 
                +FhPt+eelv +yL++kv+++k++l ++i+evd+y++ePwdL++                           +++++ewyfFs +d+ky++g+r+nrat++
  462914484  80 KFHPTEEELVGYYLARKVASQKIDL-DIIQEVDLYRIEPWDLQEryysnwqtsvlidgahaerckqgvtGGEEQTTEWYFFSYKDRKYPSGTRTNRATAA 178
                8************************.99**************955899*******999999987765432223556************************ PP

        NAM  81 gyWkatgkdkevlsk.......kgelvglkktLvfykgrapkgektdWvmheyrl 128
                g+Wkatg+dk+vls+       ++ ++g++ktLvfykgrap+g+ktdW+mheyr+
  462914484 179 GFWKATGRDKPVLSSssgggcsSRVVIGMRKTLVFYKGRAPNGRKTDWIMHEYRI 233
                **************988777766666***************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019411.12E-21680IPR003441NAC domain
PROSITE profilePS5100516.608879IPR003441NAC domain
PfamPF023653.5E-10978IPR003441NAC domain
PROSITE profilePS5100548.58475268IPR003441NAC domain
PfamPF023656.3E-2480233IPR003441NAC domain
SuperFamilySSF1019414.58E-4780268IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 405 aa     Download sequence    Send to blast
MEEESCCVPP GFRFHPTEEE LVGYYLARKV ASQKIDLDII QEVDLYRIEP WDLQERCKQG  60
VTGGEEQTTE WYFFSYKDRK FHPTEEELVG YYLARKVASQ KIDLDIIQEV DLYRIEPWDL  120
QERYYSNWQT SVLIDGAHAE RCKQGVTGGE EQTTEWYFFS YKDRKYPSGT RTNRATAAGF  180
WKATGRDKPV LSSSSGGGCS SRVVIGMRKT LVFYKGRAPN GRKTDWIMHE YRIQSNEHAP  240
PQASSPKVLS PDRWCREEGW VVCRAFQKPV PNQRPCTGLY PTPGYYDTTI LGSSSSSSSY  300
YRAAGPADAV FRPQQLPSNY YAVDDDLFES KKHLFSIPPL QSPTAISDPY QLTQRCNAAI  360
GADDHYEQGG GRPAAAIDWN FLDSLLQSTT SQLHDPTSSL PRADY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3ulx_A4e-40326810168Stress-induced transcription factor NAC1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (e.g. genes involved in secondary wall biosynthesis, cell wall modification such as xylan accumulation, and programmed cell death) (PubMed:20935069, PubMed:20488898, PubMed:22037706, PubMed:21284754). Involved in xylem formation in roots and shoots, especially regulating protoxylem vessel differentiation by promoting immature xylem vessel-specific genes expression (PubMed:16103214, PubMed:18445131, PubMed:20488898, PubMed:21498679, PubMed:21284754). Can activate the expression of several genes including XCP1, MYB46, NAC010/SND3, MYB103, MYB58, MYB63, MYB83, KNAT7, ASL19 and ASL20 (PubMed:17890373, PubMed:19088331, PubMed:18952777, PubMed:19122102, PubMed:19808805, PubMed:20935069, PubMed:21284754). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:17890373, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:18952777, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:19122102, ECO:0000269|PubMed:19808805, ECO:0000269|PubMed:20488898, ECO:0000269|PubMed:20935069, ECO:0000269|PubMed:21284754, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22037706}.; FUNCTION: Required for the soilborne fungal pathogen Verticillium longisporum-induced transdifferentiation of chloroplast-containing bundle sheath cells to functional xylem elements leading to stunted growth, vein clearing, and leaf chloroses, as well as xylem hyperplasia within the vasculature of leaves, hypocotyls, and roots due to reinitiation of cambial activity and transdifferentiation of xylem parenchyma cells. This developmental reprogramming mediates also an increased drought stress tolerance. {ECO:0000269|PubMed:23023171}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap462914484
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By brassinosteroids (e.g. brassinolide BL), auxin (e.g. 2,4-dichlorphenoxyacetic acid 2,4-D) and cytokinin (e.g. kinetin), with a synergistic effect (PubMed:16103214, PubMed:22345435). Up-regulated in a feed-back loop by ASL20 (PubMed:19088331). Levels are monitored by proteasome-mediated degradation (PubMed:18445131). Repressed by WEE1 upon replication stress to prevent premature tracheary element differentiation (PubMed:21498679). Accumulates during infection by the soilborne fungal pathogen Verticillium longisporum, especially in tissues undergoing de novo xylem formation (PubMed:23023171). {ECO:0000269|PubMed:16103214, ECO:0000269|PubMed:18445131, ECO:0000269|PubMed:19088331, ECO:0000269|PubMed:21498679, ECO:0000269|PubMed:22345435, ECO:0000269|PubMed:23023171}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002448830.11e-110NAC domain-containing protein 30
RefseqXP_021318357.11e-110NAC domain-containing protein 30
SwissprotQ9C8W98e-79NAC30_ARATH; NAC domain-containing protein 30
TrEMBLA0A499R3B51e-111A0A499R3B5_9POAL; NAC2 transcription factor
STRINGSb06g034010.11e-110(Sorghum bicolor)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP25943791
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G71930.11e-75vascular related NAC-domain protein 7
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Kakehi J, et al.
    Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana.
    PLoS ONE, 2015. 10(1): p. e0117309
    [PMID:25625317]
  3. Li Z, et al.
    A Transcriptional and Metabolic Framework for Secondary Wall Formation in Arabidopsis.
    Plant Physiol., 2016. 172(2): p. 1334-1351
    [PMID:27566165]
  4. de Lucas M, et al.
    Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation.
    Plant Cell, 2016. 28(10): p. 2616-2631
    [PMID:27650334]
  5. Tan TT, et al.
    Transcription Factors VND1-VND3 Contribute to Cotyledon Xylem Vessel Formation.
    Plant Physiol., 2018. 176(1): p. 773-789
    [PMID:29133368]
  6. Ohashi-Ito K,Iwamoto K,Fukuda H
    LOB DOMAIN-CONTAINING PROTEIN 15 Positively Regulates Expression of VND7, a Master Regulator of Tracheary Elements.
    Plant Cell Physiol., 2018. 59(5): p. 989-996
    [PMID:29444288]