PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Thhalv10013977m | ||||||||
Common Name | EUTSA_v10013977mg | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
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Family | E2F/DP | ||||||||
Protein Properties | Length: 351aa MW: 39926.4 Da PI: 9.1154 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 71.6 | 9e-23 | 11 | 76 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rkeksL++l ++flkl+++ + + + l+++a +L v +rRRiYD++N+Le+++l++++ kn+++wkg Thhalv10013977m 11 RKEKSLGVLVSNFLKLYNRDDVDLIGLDDAAGKL---GV--ERRRIYDVVNILESIGLVARRGKNQYSWKG 76 79*****************999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 77 | 1.8e-24 | 136 | 216 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 +keksL++l+q+f+kl+ +s+++ +tl+ ++k+L++ ++++k+RR+YDi+NV++++nliek ++k+++rw g Thhalv10013977m 136 KKEKSLWVLAQNFVKLFLCSDDDLITLDGATKALLNVsqdpmNMRTKVRRLYDIANVFSSMNLIEKthipeTRKPAYRWLG 216 69********************************887999***************************************87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 6.0E-24 | 7 | 77 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 7.17E-16 | 10 | 74 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.8E-26 | 11 | 76 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 8.0E-19 | 12 | 76 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 2.5E-21 | 134 | 218 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.6E-28 | 136 | 216 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 7.0E-19 | 137 | 216 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 4.67E-12 | 138 | 217 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0008284 | Biological Process | positive regulation of cell proliferation | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 351 aa Download sequence Send to blast |
MDSLGRQSYS RKEKSLGVLV SNFLKLYNRD DVDLIGLDDA AGKLGVERRR IYDVVNILES 60 IGLVARRGKN QYSWKGFGQL PRALSELKDE GMREKFGIIP CVTKSEMVLY DQVREEPLKL 120 TPDDQENSPS PKLDSKKEKS LWVLAQNFVK LFLCSDDDLI TLDGATKALL NVSQDPMNMR 180 TKVRRLYDIA NVFSSMNLIE KTHIPETRKP AYRWLGAKAI SESRFLTAPA TLCDRNEPKK 240 RVFGTEITNF NAKRNKTDCS KDSKHYGNQN TCSVIKQEQC DSKPAEKSFV VGTGGASKKN 300 NVENNHNQRL EDLETLSSTH KLQYCNHELI GLLGHYTETW RSWHAEFDRK * |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 1e-34 | 10 | 208 | 3 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent regulation of gene expression. Binds specifically the E2 recognition site as a monomer without interacting with DP proteins. May be up-regulating E2FA and down-regulating repressors of cell cycle progression. Promotes cell proliferation and represses cell elongation. Regulated by proteolysis via a ubiquitin-proteasome pathway. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:19937368}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00511 | DAP | Transfer from AT5G14960 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Thhalv10013977m |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Down-regulated posttranscroptionally by auxin. {ECO:0000269|PubMed:19937368}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_006400017.1 | 0.0 | E2F transcription factor-like E2FD | ||||
Swissprot | Q9LFQ9 | 1e-175 | E2FD_ARATH; E2F transcription factor-like E2FD | ||||
TrEMBL | V4KU26 | 0.0 | V4KU26_EUTSA; Uncharacterized protein | ||||
STRING | XP_006400017.1 | 0.0 | (Eutrema salsugineum) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM6003 | 25 | 47 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT5G14960.1 | 1e-177 | DP-E2F-like 2 |
Link Out ? help Back to Top | |
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Phytozome | Thhalv10013977m |
Entrez Gene | 18018237 |