PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | AT5G14960.1 | ||||||||
Common Name | DEL2, E2FD, E2L1, ELP3, F2G14.80 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Family | E2F/DP | ||||||||
Protein Properties | Length: 359aa MW: 40553 Da PI: 8.6432 | ||||||||
Description | DP-E2F-like 2 | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 66.4 | 3.6e-21 | 13 | 78 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL++l +fl+l+++ + + l+++a +L v +rRRiYD++N+Le+++l++++ kn+++wkg AT5G14960.1 13 RKDKSLGVLVANFLTLYNRPDVDLFGLDDAAAKL---GV--ERRRIYDVVNILESIGLVARSGKNQYSWKG 78 79****************9888************...**..****************************98 PP | |||||||
2 | E2F_TDP | 76.9 | 1.9e-24 | 138 | 217 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 rke++L+ll+q+f+kl+ +s+++ vt+++++k+L++e ++++k+RR+YDi+NV+++++liek ++k+++rw g AT5G14960.1 138 RKERTLWLLAQNFVKLFLCSDDDLVTFDSATKALLNEsqdmNMRKKVRRLYDIANVFSSMKLIEKthvpeTKKPAYRWLG 217 799******************************************************************99*******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 1.4E-22 | 11 | 79 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 3.58E-15 | 12 | 76 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 5.8E-25 | 13 | 78 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 7.4E-18 | 14 | 78 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 5.7E-20 | 135 | 219 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.0E-27 | 138 | 217 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.7E-16 | 139 | 217 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 7.21E-11 | 141 | 218 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0007049 | Biological Process | cell cycle | ||||
GO:0008284 | Biological Process | positive regulation of cell proliferation | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding | ||||
GO:0005515 | Molecular Function | protein binding |
Plant Ontology ? help Back to Top | ||||||
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PO Term | PO Category | PO Description | ||||
PO:0000037 | anatomy | shoot apex | ||||
PO:0000293 | anatomy | guard cell | ||||
PO:0008019 | anatomy | leaf lamina base | ||||
PO:0009005 | anatomy | root | ||||
PO:0009009 | anatomy | plant embryo | ||||
PO:0009010 | anatomy | seed | ||||
PO:0009025 | anatomy | vascular leaf | ||||
PO:0009031 | anatomy | sepal | ||||
PO:0009046 | anatomy | flower | ||||
PO:0009047 | anatomy | stem | ||||
PO:0009052 | anatomy | flower pedicel | ||||
PO:0009053 | anatomy | peduncle | ||||
PO:0020094 | anatomy | plant egg cell | ||||
PO:0025022 | anatomy | collective leaf structure | ||||
PO:0001078 | developmental stage | plant embryo cotyledonary stage | ||||
PO:0001081 | developmental stage | mature plant embryo stage | ||||
PO:0001185 | developmental stage | plant embryo globular stage | ||||
PO:0004507 | developmental stage | plant embryo bilateral stage | ||||
PO:0007115 | developmental stage | LP.04 four leaves visible stage | ||||
PO:0007611 | developmental stage | petal differentiation and expansion stage | ||||
PO:0007616 | developmental stage | flowering stage |
Sequence ? help Back to Top |
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Protein Sequence Length: 359 aa Download sequence Send to blast |
MDSLALAPQV YSRKDKSLGV LVANFLTLYN RPDVDLFGLD DAAAKLGVER RRIYDVVNIL 60 ESIGLVARSG KNQYSWKGFG AVPRALSELK EEGMKEKFAI VPFVAKSEMV VYEKEGEESF 120 MLSPDDQEFS PSPRPDNRKE RTLWLLAQNF VKLFLCSDDD LVTFDSATKA LLNESQDMNM 180 RKKVRRLYDI ANVFSSMKLI EKTHVPETKK PAYRWLGSKT IFENRFIDGS ASLCDRNVPK 240 KRAFGTELTN VNAKRNKSGC SKEDSKRNGN QNTSIVIKQE QCDDVKPDVK NFASGSSTPA 300 GTSESNDMGN NIRPRGRLGV IEALSTLYQP SYCNPELLGL FAHYNETFRS YQEEFGREK |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 3e-35 | 12 | 209 | 3 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Expression -- Microarray ? help Back to Top | ||||||
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Source | ID | E-value | ||||
GEO | 30685136 | 0.0 | ||||
Genevisible | 246568_at | 0.0 | ||||
Expression Atlas | AT5G14960 | - | ||||
AtGenExpress | AT5G14960 | - | ||||
ATTED-II | AT5G14960 | - |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected at the G1/S transition, but increases during the progression into S phase and peaks after the passage into G2. {ECO:0000269|PubMed:11786543}. | |||||
Uniprot | TISSUE SPECIFICITY: Preferentially expressed in proliferating tissues. Highly expressed in young stalk and young flowers. Lower expression in young leaves and mature flowers. Detected in cotyledonary vascular tissues, the shoot apical meristem, the base of trichomes, the fully developed stomata, the central root cylinder and in the columella of lateral roots but not in the primary root tips or in the leaf epidermal cells. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:19937368}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent regulation of gene expression. Binds specifically the E2 recognition site as a monomer without interacting with DP proteins. May be up-regulating E2FA and down-regulating repressors of cell cycle progression. Promotes cell proliferation and represses cell elongation. Regulated by proteolysis via a ubiquitin-proteasome pathway. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:19937368}. |
Function -- GeneRIF ? help Back to Top | ||||||
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Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00511 | DAP | 27203113 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | AT5G14960.1 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Down-regulated posttranscroptionally by auxin. {ECO:0000269|PubMed:19937368}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top | ||||||
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Source | Target Gene (A: Activate/R: Repress) | |||||
ATRM | AT2G36010(A), AT3G48160(A), AT5G22220(A) |
Phenotype -- Disruption Phenotype ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | DISRUPTION PHENOTYPE: Increased root length and smaller cotyledons. Reduced root meristematic zone but longer cells in the differentiation zone. {ECO:0000269|PubMed:19937368}. |
Phenotype -- Mutation ? help Back to Top | ||||||
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Source | ID | |||||
T-DNA Express | AT5G14960 |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | AB074531 | 0.0 | AB074531.1 Arabidopsis thaliana mRNA for E2F-like repressor E2L1, complete cds. | |||
GenBank | AJ417835 | 0.0 | AJ417835.1 Arabidopsis thaliana mRNA for transcription factor E2Fd (e2Fd gene). |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | NP_197000.1 | 0.0 | DP-E2F-like 2 | ||||
Swissprot | Q9LFQ9 | 0.0 | E2FD_ARATH; E2F transcription factor-like E2FD | ||||
TrEMBL | A0A178UM45 | 0.0 | A0A178UM45_ARATH; E2L1 | ||||
STRING | AT5G14960.1 | 0.0 | (Arabidopsis thaliana) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM6003 | 25 | 47 | Representative plant | OGRP2474 | 16 | 34 |
Link Out ? help Back to Top | |
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Phytozome | AT5G14960.1 |
Entrez Gene | 831348 |
iHOP | AT5G14960 |
wikigenes | AT5G14960 |