PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thhalv10006475m
Common NameEUTSA_v10006475mg
Organism
Eutrema salsugineum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
Family MYB
Protein Properties Length: 305aa    MW: 34529.7 Da    PI: 8.0736
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thhalv10006475mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding43.66.9e-141156146
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
                     +g+W +eEde l++ vk++G+++W++I ++  ++Rt+k+c++rw +
  Thhalv10006475m 11 KGPWKAEEDEVLINHVKRYGPRDWSSIRSKGLLRRTGKSCRLRWVN 56
                     79*************************888779***********87 PP
2Myb_DNA-binding43.47.8e-1467107345
                      SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS
  Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 
                      ++++eE+ + +++  ++G++ W++Ia +++ gRt++++k++w 
  Thhalv10006475m  67 KFSAEEERIVIELQSEFGNK-WARIATYLP-GRTDNDVKNFWS 107
                      79******************.*********.***********6 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.603.3E-21559IPR009057Homeodomain-like
PROSITE profilePS5129422.095662IPR017930Myb domain
SuperFamilySSF466893.2E-288106IPR009057Homeodomain-like
SMARTSM007171.0E-111060IPR001005SANT/Myb domain
CDDcd001675.83E-121358No hitNo description
PfamPF139217.6E-121464No hitNo description
Gene3DG3DSA:1.10.10.603.6E-1960112IPR009057Homeodomain-like
PROSITE profilePS5129419.74963114IPR017930Myb domain
SMARTSM007171.2E-1364112IPR001005SANT/Myb domain
PfamPF002491.3E-1267107IPR001005SANT/Myb domain
CDDcd001674.74E-1167106No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0048235Biological Processpollen sperm cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 305 aa     Download sequence    Send to blast
MEGAKKEDVK KGPWKAEEDE VLINHVKRYG PRDWSSIRSK GLLRRTGKSC RLRWVNKLRP  60
NLKNGCKFSA EEERIVIELQ SEFGNKWARI ATYLPGRTDN DVKNFWSSRL KRLARILHNS  120
SESTSGLNPK SSSSHRTKGK NVKPIQSFNP SQRFGLVDQE TTASSSSSKI IPYSSDQVDE  180
TLRLPELGIK LEHQPFTFGA DLVLAETTSS LFSESSQIPN QQQVSPFSPE SRELLARLDD  240
PYFYDILGPA DSSEPLFPLP QPFFEPSPAP RRCRHVSKDE DPDVFFDDFP ADMFDQVDSI  300
RSPP*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C1e-28811224126MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269|PubMed:15618418, ECO:0000269|PubMed:15694308, ECO:0000269|PubMed:19300502, ECO:0000269|PubMed:21285328, ECO:0000269|PubMed:24876252}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapThhalv10006475m
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269|PubMed:21441434, ECO:0000269|PubMed:25057814}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006402579.20.0transcription factor DUO1
SwissprotA0A178VEK71e-169DUO1_ARATH; Transcription factor DUO1
TrEMBLV4LNL00.0V4LNL0_EUTSA; Uncharacterized protein
STRINGXP_006402579.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM65512842
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G60460.11e-132MYB family protein
Publications ? help Back to Top
  1. Zheng B,He H,Zheng Y,Wu W,McCormick S
    An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana.
    PLoS Genet., 2014. 10(7): p. e1004421
    [PMID:25057814]
  2. Peters B, et al.
    A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter.
    Plant Physiol., 2017. 173(1): p. 280-293
    [PMID:27624837]
  3. Zheng Z, et al.
    Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy.
    Plant Physiol., 2017. 174(3): p. 1764-1778
    [PMID:28515145]