PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID EcS764489.10
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus
Family E2F/DP
Protein Properties Length: 148aa    MW: 16385.8 Da    PI: 9.5825
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
EcS764489.10genomeECGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP58.31.2e-1843100971
       E2F_TDP   9 ltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                   ++  fl+l+++ + +++ l+++a +L    v  +rRRiYD++N+Le+++++++k+kn+++wkg
  EcS764489.10  43 FSVPFLRLYNRDDVEVIGLDDAALKL---GV--ERRRIYDVVNILESVGVVARKAKNQYSWKG 100
                   7888******9999************...**..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM013725.9E-1838100IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467856.9E-134398IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.7E-1543100IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.109.0E-1943101IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 148 aa     Download sequence    Send to blast
AAGIRGVARF QAASLLPQGQ VPRRPLLQVV PPPLLPSPKD SSFSVPFLRL YNRDDVEVIG  60
LDDAALKLGV ERRRIYDVVN ILESVGVVAR KAKNQYSWKG FRAIPNALEK LKEEGLRENS  120
NNSNCGDPAK VLPQLEFIPF FDSAVSFE
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018718840.13e-53PREDICTED: E2F transcription factor-like E2FF isoform X3
SwissprotQ8RWL03e-35E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLA0A059ARS82e-51A0A059ARS8_EUCGR; Uncharacterized protein
STRINGXP_010029245.13e-52(Eucalyptus grandis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM2661233
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.14e-37DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]