PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

DCAR_009224

Organism

Daucus carota

Taxonomic ID

4039

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Apiales; Apiineae; Apiaceae; Apioideae; Scandiceae; Daucinae; Daucus

Family

GRAS

Protein Properties

Length: 451aa MW: 50426.5 Da PI: 5.931

Description

GRAS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
DCAR_009224	genome	ARS-USDA	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	GRAS	396.7	2.5e-121	92	445	1	374
GRAS 1 lvelLlecAeavssgdlelaqalLarlselaspdg..dpmqRlaayfteALaarlarsvselykalppsetseknsseelaalklfsevsPilkfshl 96 lv++L++cA+ v+ g l+ a+alL++l+ l s + ++aayf AL++r+++ l+ s + e+ ++ f+e++P+lkf+h+ DCAR_009224 92 LVHVLMSCADSVQRGTLSVASALLEELQVLLSRVNseFGFGKVAAYFIDALSRRVFK-------PLERSLG---SAFENEVLYHHFYEACPYLKFAHF 179 689************************96655522599************9.......3333333...35556677889********* PP GRAS 97 taNqaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgspesgskeeleetgerLakfAeelgvpfefnvlvakrledleleeL 194 t NqaIlea++g+ +vH+iDf+++qGlQWpaL+qaLa Rp+gpp+lRiTg+g+ + + ++ l+etg rLa++A++++v+f f+ ++a++++d++l++L DCAR_009224 180 TSNQAILEAFDGQACVHVIDFNLMQGLQWPALIQALALRPNGPPTLRITGIGPVSLDGHDPLRETGLRLAQLARSVNVRFAFRGVAASNIDDVKLWML 277 *************************************************9999************************************* PP GRAS 195 rvkpgEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnsesFlerflealeyysalfdsleaklpreseerikvErellgr 292 +v+p+Ea+aVn+++qlh+lld++ ++s vLkl+ sl Pk+v++veq+++hn+++F ++f eal+yys++fdslea + ++++ + +++r DCAR_009224 278 QVDPKEAVAVNCIMQLHKLLDDPSRIDS----VLKLIHSLDPKIVTLVEQDTNHNQPDFSDKFREALDYYSTMFDSLEAC----KGPQKWLAEIYIQR 367 ****************88777777....*****************************************999....788999999* PP GRAS 293 eivnvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvk.sdgyrveeesgslvlgWkdrpLvsvSaWr 374 ei++vv+c++ he l++Wrer+++ GF++v l+ +a+kqa++ll ++ + gyrv+e++g+l lgW++rpL+++SaWr DCAR_009224 368 EICSVVCCAEM-----HEPLAQWRERMSRNGFTSVCLGANAYKQANMLLTVFSaQGGYRVDESEGCLKLGWHNRPLIAASAWR 445 ****987.....5********************************8888***********************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF12041	8.6E-7	30	61	IPR021914	Transcriptional factor DELLA, N-terminal
PROSITE profile	PS50985	58.027	66	424	IPR005202	Transcription factor GRAS
Pfam	PF03514	8.6E-119	92	445	IPR005202	Transcription factor GRAS

Sequence ? help Back to Top
Protein Sequence Length: 451 aa Download sequence Send to blast
MSFKSNCSSS LPPLLAAANY TTIPSPLSEL TQLHNENTLL NNPSELSSWV DSLLTEFNQP 60 TSINNITAWN DYNTTSYCNI RQIIEEDSSI RLVHVLMSCA DSVQRGTLSV ASALLEELQV 120 LLSRVNSEFG FGKVAAYFID ALSRRVFKPL ERSLGSAFEN EVLYHHFYEA CPYLKFAHFT 180 SNQAILEAFD GQACVHVIDF NLMQGLQWPA LIQALALRPN GPPTLRITGI GPVSLDGHDP 240 LRETGLRLAQ LARSVNVRFA FRGVAASNID DVKLWMLQVD PKEAVAVNCI MQLHKLLDDP 300 SRIDSVLKLI HSLDPKIVTL VEQDTNHNQP DFSDKFREAL DYYSTMFDSL EACKGPQKWL 360 AEIYIQREIC SVVCCAEMHE PLAQWRERMS RNGFTSVCLG ANAYKQANML LTVFSAQGGY 420 RVDESEGCLK LGWHNRPLIA ASAWRPNPRL *

Sequence ? help Back to Top

Protein Sequence Length: 451 aa Download sequence Send to blast

MSFKSNCSSS LPPLLAAANY TTIPSPLSEL TQLHNENTLL NNPSELSSWV DSLLTEFNQP  60
TSINNITAWN DYNTTSYCNI RQIIEEDSSI RLVHVLMSCA DSVQRGTLSV ASALLEELQV  120
LLSRVNSEFG FGKVAAYFID ALSRRVFKPL ERSLGSAFEN EVLYHHFYEA CPYLKFAHFT  180
SNQAILEAFD GQACVHVIDF NLMQGLQWPA LIQALALRPN GPPTLRITGI GPVSLDGHDP  240
LRETGLRLAQ LARSVNVRFA FRGVAASNID DVKLWMLQVD PKEAVAVNCI MQLHKLLDDP  300
SRIDSVLKLI HSLDPKIVTL VEQDTNHNQP DFSDKFREAL DYYSTMFDSL EACKGPQKWL  360
AEIYIQREIC SVVCCAEMHE PLAQWRERMS RNGFTSVCLG ANAYKQANML LTVFSAQGGY  420
RVDESEGCLK LGWHNRPLIA ASAWRPNPRL *

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3g_A	3e-59	99	446	26	380	Protein SCARECROW
5b3h_A	2e-59	99	446	25	379	Protein SCARECROW
5b3h_D	2e-59	99	446	25	379	Protein SCARECROW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Transcription coactivator of the zinc finger transcription factors GAF1/IDD2 and ENY/IDD1 in regulation of gibberellin homeostasis and signaling (PubMed:25035403). No effect of the BOI proteins on its stability. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression. In contrast to RGA, it is less sensitive to GA. Its activity is probably regulated by other phytohormones such as auxin and ethylene. {ECO:0000269\|PubMed:11487693, ECO:0000269\|PubMed:11606551, ECO:0000269\|PubMed:11606552, ECO:0000269\|PubMed:14973286, ECO:0000269\|PubMed:15128937, ECO:0000269\|PubMed:16034591, ECO:0000269\|PubMed:17933900, ECO:0000269\|PubMed:25035403, ECO:0000269\|PubMed:9389651}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_017238853.1	0.0	PREDICTED: DELLA protein GAI-like
Swissprot	Q9LQT8	1e-135	GAI_ARATH; DELLA protein GAI
TrEMBL	A0A165ZV69	0.0	A0A165ZV69_DAUCS; Uncharacterized protein
STRING	Aquca_001_00705.1	0.0	(Aquilegia coerulea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA15141	5	8

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G14920.1	1e-137	GRAS family protein

Link Out ? help Back to Top
Phytozome	DCAR_009224

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Gallego-Giraldo C, et al. Role of the gibberellin receptors GID1 during fruit-set in Arabidopsis. Plant J., 2014. 79(6): p. 1020-1032 [PMID:24961590] Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Marín-de la Rosa N, et al. Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins. PLoS Genet., 2015. 11(7): p. e1005337 [PMID:26134422] Shi H,Wei Y,Wang Q,Reiter RJ,He C Melatonin mediates the stabilization of DELLA proteins to repress the floral transition in Arabidopsis. J. Pineal Res., 2016. 60(3): p. 373-9 [PMID:26887824] Lee SA, et al. Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue. Mol Plant, 2016. 9(6): p. 870-84 [PMID:26970019] Qu J,Kang SG,Hah C,Jang JC Molecular and cellular characterization of GA-Stimulated Transcripts GASA4 and GASA6 in Arabidopsis thaliana. Plant Sci., 2016. 246: p. 1-10 [PMID:26993231] Shahnejat-Bushehri S,Nobmann B,Devi Allu A,Balazadeh S JUB1 suppresses Pseudomonas syringae-induced defense responses through accumulation of DELLA proteins. Plant Signal Behav, 2016. 11(6): p. e1181245 [PMID:27159137] Shahnejat-Bushehri S,Tarkowska D,Sakuraba Y,Balazadeh S Arabidopsis NAC transcription factor JUB1 regulates GA/BR metabolism and signalling. Nat Plants, 2016. 2: p. 16013 [PMID:27249348] Wang H, et al. The DELLA-CONSTANS Transcription Factor Cascade Integrates Gibberellic Acid and Photoperiod Signaling to Regulate Flowering. Plant Physiol., 2016. 172(1): p. 479-88 [PMID:27406167] Li W,Wang H,Yu D Arabidopsis WRKY Transcription Factors WRKY12 and WRKY13 Oppositely Regulate Flowering under Short-Day Conditions. Mol Plant, 2016. 9(11): p. 1492-1503 [PMID:27592586] Liu B,De Storme N,Geelen D Gibberellin Induces Diploid Pollen Formation by Interfering with Meiotic Cytokinesis. Plant Physiol., 2017. 173(1): p. 338-353 [PMID:27621423] Matsuoka K, et al. Differential Cellular Control by Cotyledon-Derived Phytohormones Involved in Graft Reunion of Arabidopsis Hypocotyls. Plant Cell Physiol., 2016. 57(12): p. 2620-2631 [PMID:27986917] Zentella R, et al. The Arabidopsis O-fucosyltransferase SPINDLY activates nuclear growth repressor DELLA. Nat. Chem. Biol., 2017. 13(5): p. 479-485 [PMID:28244988] Zhang Y, et al. GA-DELLA pathway is involved in regulation of nitrogen deficiency-induced anthocyanin accumulation. Plant Cell Rep., 2017. 36(4): p. 557-569 [PMID:28275852] Zhang L,Chen L,Yu D Transcription Factor WRKY75 Interacts with DELLA Proteins to Affect Flowering. Plant Physiol., 2018. 176(1): p. 790-803 [PMID:29133369] Nelson SK,Ariizumi T,Steber CM Biology in the Dry Seed: Transcriptome Changes Associated with Dry Seed Dormancy and Dormancy Loss in the Arabidopsis GA-Insensitive sleepy1-2 Mutant. Front Plant Sci, 2017. 8: p. 2158 [PMID:29312402] Liu B,De Storme N,Geelen D Cold-Induced Male Meiotic Restitution in Arabidopsis thaliana Is Not Mediated by GA-DELLA Signaling. Front Plant Sci, 2018. 9: p. 91 [PMID:29459879] Zhang Y, et al. DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6. Plant Cell Rep., 2018. 37(7): p. 981-992 [PMID:29574486] Felipo-Benavent A, et al. Regulation of xylem fiber differentiation by gibberellins through DELLA-KNAT1 interaction. Development, 2019. [PMID:30389856] Wright DA, et al. Recovery of YAC-end sequences through complementation of an Escherichia coli pyrF mutation. Nucleic Acids Res., 1997. 25(13): p. 2679-80 [PMID:9185581]