PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID orange1.1g048459m
Common NameCISIN_1g048459mg
Organism
Citrus sinensis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus
Family C2H2
Protein Properties Length: 363aa    MW: 42207.9 Da    PI: 8.4585
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
orange1.1g048459mgenomeICGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H221.37e-076889223
                       EETTTTEEESSHHHHHHHHHHT CS
            zf-C2H2  2 kCpdCgksFsrksnLkrHirtH 23
                       +C+ Cg sF+ + +Lk+H+ +H
  orange1.1g048459m 68 TCEECGASFKKPAYLKQHMLSH 89
                       7*******************99 PP
2zf-C2H217.61.1e-0595119123
                        EEET..TTTEEESSHHHHHHHHHHT CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                        ++C+  dC+ s++rk++L+rH+ +H
  orange1.1g048459m  95 FRCSvdDCHASYRRKDHLTRHLLRH 119
                        89*********************99 PP
3zf-C2H215.26.1e-05124149123
                        EEET..TTTEEESSHHHHHHHHHH.T CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                        +kCp  +C++ F+ + n+krH +  H
  orange1.1g048459m 124 FKCPieNCNREFTIQGNMKRHVKElH 149
                        89********************9986 PP
4zf-C2H218.27e-06164188123
                        EEET..TTTEEESSHHHHHHHHHHT CS
            zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                        y C+   Cgk+F+  s L++H  +H
  orange1.1g048459m 164 YICQeiGCGKVFKYASKLRQHEDSH 188
                        89*******************9888 PP
5zf-C2H215.45.3e-05255279223
                        EET..TTTEEESSHHHHHHHHHH.T CS
            zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                        kC+   C  sFs++snL++H +  H
  orange1.1g048459m 255 KCQfkGCLLSFSTNSNLRQHVKAvH 279
                        688889**************99877 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS501578.7042552IPR007087Zinc finger, C2H2
SMARTSM00355232547IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.5286794IPR007087Zinc finger, C2H2
SMARTSM003550.00886789IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.606.6E-76888IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.95E-1068119No hitNo description
PROSITE patternPS0002806989IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.608.0E-1189121IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.82795124IPR007087Zinc finger, C2H2
SMARTSM003550.006695119IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028097119IPR007087Zinc finger, C2H2
SuperFamilySSF576671.49E-6122150No hitNo description
Gene3DG3DSA:3.30.160.602.4E-6122146IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.637124155IPR007087Zinc finger, C2H2
SMARTSM003550.0015124149IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280126150IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.609.0E-8156188IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576672.39E-5160188No hitNo description
PROSITE profilePS5015711.24164193IPR007087Zinc finger, C2H2
SMARTSM003550.0033164188IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280166188IPR007087Zinc finger, C2H2
SMARTSM003551.1196221IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280198221IPR007087Zinc finger, C2H2
SMARTSM0035520224245IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.605.2E-6235276IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576672.7E-8236292No hitNo description
PROSITE profilePS5015710.928254284IPR007087Zinc finger, C2H2
SMARTSM003550.011254279IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280256279IPR007087Zinc finger, C2H2
SMARTSM003558.6285310IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280287311IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008097Molecular Function5S rRNA binding
GO:0046872Molecular Functionmetal ion binding
GO:0080084Molecular Function5S rDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 363 aa     Download sequence    Send to blast
MEEVSDMEEE KGLEERPKSR DVRRYYCDYC GICRSKKSLI LSHIASHHKE DEERVDGDGE  60
TKGVQCNTCE ECGASFKKPA YLKQHMLSHL LERPFRCSVD DCHASYRRKD HLTRHLLRHQ  120
GKLFKCPIEN CNREFTIQGN MKRHVKELHH EGTTSTDSGD QKQYICQEIG CGKVFKYASK  180
LRQHEDSHVN LDSVEAFCSE PGCMKYFTNK QCLEAHIRSC HQYIPCEICG SMQLKKNIKR  240
HVRTHEARDL SERIKCQFKG CLLSFSTNSN LRQHVKAVHY EIKPFACSFF GCGMRFAFKH  300
VRDNHEKSGH HVYSSGDFVE SDERFRSRER GGRKRKCPTV EMLIRKRVSL PSPTQSCNLY  360
ED*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tf6_A2e-167122719165PROTEIN (TRANSCRIPTION FACTOR IIIA)
1tf6_D2e-167122719165PROTEIN (TRANSCRIPTION FACTOR IIIA)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Both isoforms 1 and 2 transcripts are expressed in seedlings and both TFIIIA and TFIIIA-C are present at similar ratios in 10-day-old seedlings (at protein level). In correlation with the reorganization of 5S rDNA chromatin to a mature state, full-length isoform 1 protein TFIIIA with transcriptional activity accumulates and permits de novo transcription of 5S rRNA. Isoforms 1 and 2 transcripts accumulate in various tissues of the reproductive phase, including flowers and siliques, but only isoform 2 is present in mature seeds. In flowers, both TFIIIA and TFIIIA-C are present at similar ratios (at protein level). Very low amounts of TFIIIA are found in extracts from fresh siliques compared to TFIIIA-C. The amount of full-length TFIIIA protein progressively increases from fresh siliques to seeds concomitant with lower proportions of the shorter TFIIIA-C protein (at protein level) thus leading to 5S rRNA accumulation in the seed. {ECO:0000269|PubMed:22353599}.
UniprotTISSUE SPECIFICITY: Expressed in seedlings, flowers, siliques and seeds. {ECO:0000269|PubMed:22353599}.
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00229DAPTransfer from AT1G72050Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006482413.10.0transcription factor IIIA isoform X1
SwissprotQ84MZ41e-142TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A067FY650.0A0A067FY65_CITSI; Uncharacterized protein
STRINGXP_006482413.10.0(Citrus sinensis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM47142852
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.21e-136transcription factor IIIA