PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID orange1.1g027872m
Common NameCISIN_1g026846mg
Organism
Citrus sinensis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus
Family C2H2
Protein Properties Length: 218aa    MW: 24890 Da    PI: 5.1246
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
orange1.1g027872mgenomeICGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H218.84.6e-061034123
                       EEET..TTTEEESSHHHHHHHHHHT CS
            zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
                       + Cp  dCgk++ + + Lk+Hi +H
  orange1.1g027872m 10 HICPypDCGKRYAHEYKLKNHIASH 34
                       679999*****************96 PP
2zf-C2H2140.000157398123
                       EEET..TTTEEESSHHHHHHHHHH.T CS
            zf-C2H2  1 ykCp..dCgksFsrksnLkrHirt.H 23
                       y Cp   C k + + + Lk H+++ H
  orange1.1g027872m 73 YACPyeGCEKAYIHEYKLKLHLKReH 98
                       89*********************999 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.602.5E-9136IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576671.36E-6136No hitNo description
PROSITE profilePS501579.4731039IPR007087Zinc finger, C2H2
SMARTSM003550.00281034IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002801235IPR007087Zinc finger, C2H2
SuperFamilySSF576673.36E-66896No hitNo description
Gene3DG3DSA:3.30.160.602.2E-96995IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0127398IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.6673103IPR007087Zinc finger, C2H2
PROSITE patternPS0002807598IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 218 aa     Download sequence    Send to blast
MKTHSQENYH ICPYPDCGKR YAHEYKLKNH IASHHEKNAA VEVPRYATPP ERITKTPKPP  60
AGVYGSASSE RPYACPYEGC EKAYIHEYKL KLHLKREHPG HMSDENAENA TTNADNEMDE  120
GSDQDAYAGK RVNGKSQKQS RAKPNLKMPP AKVTQRKSST PSPATLNVVR KQQWTPKEEV  180
YEEEDSEETE EDRDNVEDGF RYGENNEDDD EETEYED*
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Rapidly induced following seed germination, especially in tender cotyledons. {ECO:0000269|PubMed:26961720}.
UniprotTISSUE SPECIFICITY: Mostly expressed in flowers, to a lower extent in seedlings, stems and leaves, and, at low levels, in roots and senescent leaves. {ECO:0000269|PubMed:26961720}.
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006494375.11e-159zinc finger transcription factor YY1-like
SwissprotQ2V3L36e-73YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A067D3R61e-159A0A067D3R6_CITSI; Uncharacterized protein
STRINGXP_006494375.11e-158(Citrus sinensis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.22e-67C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]