PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

orange1.1g026846m

Common Name

CISIN_1g026846mg

Organism

Citrus sinensis

Taxonomic ID

2711

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus

Family

C2H2

Protein Properties

Length: 233aa MW: 26608 Da PI: 5.4158

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
orange1.1g026846m	genome	ICGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	18.6	5e-06	25	49	1	23
EEET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirtH 23 + Cp dCgk++ + + Lk+Hi +H orange1.1g026846m 25 HICPypDCGKRYAHEYKLKNHIASH 49 679999*****************96 PP
2	zf-C2H2	13.8	0.00017	88	113	1	23
EEET..TTTEEESSHHHHHHHHHH.T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt.H 23 y Cp C k + + + Lk H+++ H orange1.1g026846m 88 YACPyeGCEKAYIHEYKLKLHLKReH 113 89*********************999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.17E-9	5	51	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.4E-11	11	51	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.0028	25	49	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	9.473	25	54	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	27	50	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	3.73E-6	83	111	No hit	No description
Gene3D	G3DSA:3.30.160.60	2.4E-9	84	110	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.012	88	113	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	9.66	88	118	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	90	113	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 233 aa Download sequence Send to blast
MKAVAFSLDF NLRSHMKTHS QENYHICPYP DCGKRYAHEY KLKNHIASHH EKNAAVEVPR 60 YATPPERITK TPKPPAGVYG SASSERPYAC PYEGCEKAYI HEYKLKLHLK REHPGHMSDE 120 NAENATTNAD NEMDEGSDQD AYAGKRVNGK SQKQSRAKPN LKMPPAKVTQ RKSSTPSPAT 180 LNVVRKQQWT PKEEVYEEED SEETEEDRDN VEDGFRYGEN NEDDDEETEY ED*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Rapidly induced following seed germination, especially in tender cotyledons. {ECO:0000269\|PubMed:26961720}.
Uniprot	TISSUE SPECIFICITY: Mostly expressed in flowers, to a lower extent in seedlings, stems and leaves, and, at low levels, in roots and senescent leaves. {ECO:0000269\|PubMed:26961720}.

Functional Description ? help Back to Top
Source	Description
UniProt	Dual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269\|PubMed:22508367, ECO:0000269\|PubMed:24451981, ECO:0000269\|PubMed:26961720}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269\|PubMed:26961720}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006494375.1	1e-168	zinc finger transcription factor YY1-like
Refseq	XP_024040742.1	1e-168	zinc finger transcription factor YY1
Swissprot	Q2V3L3	3e-82	YY1_ARATH; Zinc finger transcription factor YY1
TrEMBL	A0A067D3R6	1e-172	A0A067D3R6_CITSI; Uncharacterized protein
STRING	XP_006494375.1	1e-168	(Citrus sinensis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5859	28	46

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G06634.2	1e-76	C2H2 family protein

Link Out ? help Back to Top
Phytozome	orange1.1g026846m

Publications ? help Back to Top
Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4. DNA Res., 2001. 8(6): p. 285-90 [PMID:11853315] Li T,Wu XY,Li H,Song JH,Liu JY A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network. Mol Plant, 2016. 9(5): p. 650-661 [PMID:26961720] Wu XY,Li T A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response. Front Plant Sci, 2017. 8: p. 323 [PMID:28348572]