PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.302640.2
Organism
Cucumis sativus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family MIKC_MADS
Protein Properties Length: 184aa    MW: 21464.1 Da    PI: 9.395
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.302640.2genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF96.98.3e-31959151
                    S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
          SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                    krien + rqvtfskRrng+lKKA+ELSvLCdaeva+iifs++gklye+s+
  Cucsa.302640.2  9 KRIENATSRQVTFSKRRNGLLKKAFELSVLCDAEVALIIFSPRGKLYEFSN 59
                    79***********************************************95 PP
2K-box69.61e-23891721798
           K-box  17 lqqela..kLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkkl 98 
                     l++e++   + k++e L+  +R+llG++L+ +s+ eLqqLe+qLe+sl+kiRs+K+++l+++i +l++ ek+l een aL+ k+
  Cucsa.302640.2  89 LEKEYDsfSMTKKLEHLEVCKRKLLGDGLDLCSIDELQQLERQLERSLSKIRSRKYQMLKDEIMKLKEEEKMLLEENAALQIKV 172
                     44444422689*********************************************************************9886 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004321.1E-39160IPR002100Transcription factor, MADS-box
PROSITE profilePS5006631.286161IPR002100Transcription factor, MADS-box
SuperFamilySSF554552.75E-33381IPR002100Transcription factor, MADS-box
PRINTSPR004045.0E-31323IPR002100Transcription factor, MADS-box
CDDcd002652.17E-42378No hitNo description
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
PfamPF003193.8E-271057IPR002100Transcription factor, MADS-box
PRINTSPR004045.0E-312338IPR002100Transcription factor, MADS-box
PRINTSPR004045.0E-313859IPR002100Transcription factor, MADS-box
PROSITE profilePS5129713.20288178IPR002487Transcription factor, K-box
PfamPF014862.3E-2289172IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010048Biological Processvernalization response
GO:0048510Biological Processregulation of timing of transition from vegetative to reproductive phase
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 184 aa     Download sequence    Send to blast
MVRGKTQMKR IENATSRQVT FSKRRNGLLK KAFELSVLCD AEVALIIFSP RGKLYEFSNC  60
SMNKTIDRYQ NRTKDLMSSN STAIEDVQLE KEYDSFSMTK KLEHLEVCKR KLLGDGLDLC  120
SIDELQQLER QLERSLSKIR SRKYQMLKDE IMKLKEEEKM LLEENAALQI KVIQYMLSLL  180
FFS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6bz1_A9e-19184184MEF2 CHIMERA
6bz1_B9e-19184184MEF2 CHIMERA
6bz1_C9e-19184184MEF2 CHIMERA
6bz1_D9e-19184184MEF2 CHIMERA
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor that promotes flowering, especially in response to vernalization by short periods of cold, in an FLC-inpedendent manner. {ECO:0000269|PubMed:16778081}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Maintained at very low levels by the polycomb-group (PcG) proteins MSI1, CLF, and EMF2 via histone methylation (H3K27me3). Derepressed upon cold treatment (vernalization). {ECO:0000269|PubMed:16778081}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818953e-94LN681895.1 Cucumis melo genomic scaffold, anchoredscaffold00005.
GenBankLN7132633e-94LN713263.1 Cucumis melo genomic chromosome, chr_9.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011654776.11e-122PREDICTED: agamous-like MADS-box protein AGL19
SwissprotO827431e-72AGL19_ARATH; Agamous-like MADS-box protein AGL19
TrEMBLA0A1S3AT261e-117A0A1S3AT26_CUCME; agamous-like MADS-box protein AGL19
STRINGXP_004143998.11e-121(Cucumis sativus)
STRINGXP_004166995.11e-121(Cucumis sativus)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G45660.14e-57AGAMOUS-like 20
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Suter L,Rüegg M,Zemp N,Hennig L,Widmer A
    Gene regulatory variation mediates flowering responses to vernalization along an altitudinal gradient in Arabidopsis.
    Plant Physiol., 2014. 166(4): p. 1928-42
    [PMID:25339407]