PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

PK04229.1

Organism

Cannabis sativa

Taxonomic ID

3483

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis

Family

E2F/DP

Protein Properties

Length: 94aa MW: 10495.8 Da PI: 8.4628

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PK04229.1	genome	CCBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	39.2	1.1e-12	9	39	39	71
E2F_TDP 39 vknkrRRiYDilNVLealnliekkekneirwkg 71 v +rRR YD++N+Le ++++++k+kn+++wkg PK04229.1 9 V--ERRRMYDVVNILEIIGVVARKAKNQYTWKG 39 5..8***************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM01372	0.0028	1	39	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	5.98E-8	6	40	IPR011991	Winged helix-turn-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	3.7E-12	7	40	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	2.9E-10	9	39	IPR003316	E2F/DP family, winged-helix DNA-binding domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 94 aa Download sequence Send to blast
MTLLLXLGVE RRRMYDVVNI LEIIGVVARK AKNQYTWKGL GEIPRALQQL KDEGLKENFS 60 ASVSCSSSRV LNDKELSGVL SLNSKEEEYS SVSS

Functional Description ? help Back to Top
Source	Description
UniProt	Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11867638, ECO:0000269\|PubMed:15308755}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024018493.1	2e-34	E2F transcription factor-like E2FF
Swissprot	Q8RWL0	4e-26	E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBL	A0A2P5CEB4	7e-36	A0A2P5CEB4_PARAD; E2F Family
STRING	XP_010091943.1	1e-33	(Morus notabilis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G01330.1	2e-26	DP-E2F-like protein 3

Publications ? help Back to Top
Dohmann EM, et al. The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability. Development, 2008. 135(11): p. 2013-22 [PMID:18434413]