PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Carubv10014041m
Common NameCARUB_v10014041mg
Organism
Capsella rubella
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family E2F/DP
Protein Properties Length: 361aa    MW: 40875.8 Da    PI: 7.4963
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Carubv10014041mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP69.93e-222186171
          E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                     rkeksL++l ++fl+l+++ +++++ l+++a +L    v  +rRRiYD++N+Le++++++++ kn ++wkg
  Carubv10014041m 21 RKEKSLGVLVSNFLRLYNRDDADQIGLDDAAGQL---GV--ERRRIYDVVNILESIGIVARRGKNMYSWKG 86
                     79********************************...**..****************************98 PP
2E2F_TDP85.73.6e-27150230171
          E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                      rkeksL+ll+q+f+k++ +s+++ +tl+++ak+L+s+     ++++k+RR+YDi+NV++++nliek     ++k+++rw g
  Carubv10014041m 150 RKEKSLWLLSQNFVKMFLCSDDDLITLDSAAKALLSDsqdpvHMRTKVRRLYDIANVFSSMNLIEKthipeTKKPAYRWLG 230
                      79********************************************************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.3E-231887IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.86E-152084IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.1E-252186IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.3E-182286IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.107.5E-23147232IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013726.9E-33150230IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023197.5E-20151230IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.47E-13152231IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 361 aa     Download sequence    Send to blast
MMSSAIVTHD VESLALQSYS RKEKSLGVLV SNFLRLYNRD DADQIGLDDA AGQLGVERRR  60
IYDVVNILES IGIVARRGKN MYSWKGFGEV PRSLNELKEE GMRERLGDSS TNNSDKISND  120
GEREEESFSF TPDDQENSSS SKIVPFSDQR KEKSLWLLSQ NFVKMFLCSD DDLITLDSAA  180
KALLSDSQDP VHMRTKVRRL YDIANVFSSM NLIEKTHIPE TKKPAYRWLG SDSIAEKGTS  240
LFNSDEPKKR VFGREITNLR AKRSKTDCSS NCKQIGYKKH DEENTEQELK PVASKYVFGP  300
FSPTGGAKRN DNVGKGRLLE IESLAASATY RPQYCNQEIT SLFGHYTEAW KKWFAELDRK  360
*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A4e-35202223228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapCarubv10014041m
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006297996.10.0E2F transcription factor-like E2FF
SwissprotQ8RWL00.0E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLR0HMF00.0R0HMF0_9BRAS; Uncharacterized protein
STRINGXP_006297996.10.0(Capsella rubella)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.10.0DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]