PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Carubv10001291m
Common NameCARUB_v10001291mg
Organism
Capsella rubella
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family E2F/DP
Protein Properties Length: 353aa    MW: 40257.6 Da    PI: 8.7091
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Carubv10001291mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP67.91.2e-211176171
          E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                     rkeksL++l ++fl+l+++   + + l+e+a  L    v  +rRRiYD++N+Le+++l++++ kn+++w+g
  Carubv10001291m 11 RKEKSLGVLVSNFLRLYNRDVGDLIGLDEAAGYL---GV--ERRRIYDVVNILESIGLVARRGKNQYSWRG 76
                     79*****************999************...**..****************************98 PP
2E2F_TDP82.92.7e-26136215171
          E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek....kekneirwkg 71 
                      +ke+sL++l+q+f+kl+ +s+++ +tl+e++k+L+++     ++++k+RR+YDi+NV++++nliek    ++k ++rw g
  Carubv10001291m 136 KKERSLWHLSQNFVKLFLCSDDDLITLDEATKALLHDsqdplNMRTKVRRLYDIANVFSSMNLIEKthtpEKKTAYRWLG 215
                      699***************************************************************9999999*****87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.5E-22977IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.8E-241176IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.5E-151174IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023193.7E-181276IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.106.1E-22134216IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013726.3E-30136215IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.9E-19137215IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467856.53E-13139216IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 353 aa     Download sequence    Send to blast
MDSLGLQPYC RKEKSLGVLV SNFLRLYNRD VGDLIGLDEA AGYLGVERRR IYDVVNILES  60
IGLVARRGKN QYSWRGFGEV PRALTELKRQ GMGEKFGIIP YVTKSEMVLY EKEREESLEF  120
TPEDQENSPS PKLDSKKERS LWHLSQNFVK LFLCSDDDLI TLDEATKALL HDSQDPLNMR  180
TKVRRLYDIA NVFSSMNLIE KTHTPEKKTA YRWLGARAIS VNRFLTASAS LCDRSEPKKR  240
AFGTELTNFN AKRNKAECSK DRKHYGNQNT SSVIKEEPYD ENPDVKNFAF GSSTPAGTSG  300
MNNIGNNIRL RLGFIETISS LYQPQYCNPA LFGLLAHYKE TFEACQEEFR RK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A3e-3572081228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent regulation of gene expression. Binds specifically the E2 recognition site as a monomer without interacting with DP proteins. May be up-regulating E2FA and down-regulating repressors of cell cycle progression. Promotes cell proliferation and represses cell elongation. Regulated by proteolysis via a ubiquitin-proteasome pathway. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:19937368}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00511DAPTransfer from AT5G14960Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCarubv10001291m
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated posttranscroptionally by auxin. {ECO:0000269|PubMed:19937368}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006288061.10.0E2F transcription factor-like E2FD
SwissprotQ9LFQ90.0E2FD_ARATH; E2F transcription factor-like E2FD
TrEMBLR0GVN70.0R0GVN7_9BRAS; Uncharacterized protein
STRINGXP_006288061.10.0(Capsella rubella)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G14960.10.0DP-E2F-like 2