PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_10701_iso_1

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

bZIP

Protein Properties

Length: 289aa MW: 31407 Da PI: 7.2983

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_10701_iso_1	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	30.2	9.8e-10	201	259	5	63
CHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 5 krerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklksev 63 kr++r NR +A rs +RK ++ eLe+kv++L++e ++L ++ +l+ l++e+ cra_locus_10701_iso_1_len_1936_ver_3 201 KRAKRILANRQSAARSKERKMRYTSELERKVQTLQTEATTLSAQVTMLQRDTTGLTAEN 259 9********************************************99998888777776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00338	1.0E-16	197	261	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	11.174	199	262	IPR004827	Basic-leucine zipper domain
Pfam	PF07716	3.3E-8	199	250	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	3.09E-11	201	253	No hit	No description
Gene3D	G3DSA:1.20.5.170	8.4E-12	201	255	No hit	No description
CDD	cd14703	2.13E-22	202	251	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0007231	Biological Process	osmosensory signaling pathway
GO:0008272	Biological Process	sulfate transport
GO:0009294	Biological Process	DNA mediated transformation
GO:0009652	Biological Process	thigmotropism
GO:0009970	Biological Process	cellular response to sulfate starvation
GO:0045596	Biological Process	negative regulation of cell differentiation
GO:0051170	Biological Process	nuclear import
GO:0005634	Cellular Component	nucleus
GO:0005829	Cellular Component	cytosol
GO:0003682	Molecular Function	chromatin binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0043621	Molecular Function	protein self-association
GO:0051019	Molecular Function	mitogen-activated protein kinase binding

Sequence ? help Back to Top
Protein Sequence Length: 289 aa Download sequence Send to blast
MDPKFTGKPI AAAQHLMSSG GGGRPEVDLD QMPDTPNRRA YHRRAQSETF FRFPDFDDDI 60 LLDDVVFDLP PAPSLSSDSN SNPNSMQQLQ AAATAKSNNS SAQVEAQPVR PEGKVHFRSL 120 SVDADFFEGL NFGASSSSSA DCAGGSAPSA AAVAGPRHRH SNSMDGSASA MTSSFEAMMV 180 DSTKKAMGAD RLQELALIDP KRAKRILANR QSAARSKERK MRYTSELERK VQTLQTEATT 240 LSAQVTMLQR DTTGLTAENK ELKLRLQAME QQAHLRDGMH HAPSTFSSY

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds specifically to the VIP1 response elements (VREs) DNA sequence 5'-ACNGCT-3' found in some stress genes (e.g. TRX8 and MYB44), when phosphorylated/activated by MPK3. Required for Agrobacterium VirE2 nuclear import and tumorigenicity. Promotes transient expression of T-DNA in early stages by interacting with VirE2 in complex with the T-DNA and facilitating its translocation to the nucleus, and mediates stable genetic transformation by Agrobacterium by binding H2A histone. Prevents cell differentiation and shoot formation. Limits sulfate utilization efficiency (SUE) and sulfate uptake, especially in low-sulfur conditions. {ECO:0000269\|PubMed:11432846, ECO:0000269\|PubMed:12124400, ECO:0000269\|PubMed:15108305, ECO:0000269\|PubMed:15824315, ECO:0000269\|PubMed:17947581, ECO:0000269\|PubMed:19820165, ECO:0000269\|PubMed:20547563}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00184	DAP	Transfer from AT1G43700	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Transcriptionally activated during the acquisition of pluripotentiality (in protoplasts) by pericentromeric chromatin decondensation and DNA demethylation. Targeted to degradation by the proteasome by VBF and Agrobacterium virF in SCF(VBF) and SCF(virF) E3 ubiquitin ligase complexes after mediating T-DNA translocation to the nucleus. {ECO:0000269\|PubMed:15108305}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027149850.1	1e-109	transcription factor VIP1
Swissprot	Q9MA75	6e-64	VIP1_ARATH; Transcription factor VIP1
TrEMBL	A0A2J6JWI8	1e-101	A0A2J6JWI8_LACSA; Uncharacterized protein
STRING	Aquca_023_00109.1	7e-90	(Aquilegia coerulea)
STRING	Migut.N03219.1.p	2e-90	(Erythranthe guttata)

Publications ? help Back to Top
Wang Y, et al. The putative Agrobacterium transcriptional activator-like virulence protein VirD5 may target T-complex to prevent the degradation of coat proteins in the plant cell nucleus. New Phytol., 2014. 203(4): p. 1266-81 [PMID:24865527] Xu DB, et al. A G-protein β subunit, AGB1, negatively regulates the ABA response and drought tolerance by down-regulating AtMPK6-related pathway in Arabidopsis. PLoS ONE, 2015. 10(1): p. e0116385 [PMID:25635681] Chen J, et al. ZmbZIP91 regulates expression of starch synthesis-related genes by binding to ACTCAT elements in their promoters. J. Exp. Bot., 2016. 67(5): p. 1327-38 [PMID:26689855] Tsugama D,Liu S,Takano T VIP1 is very important/interesting protein 1 regulating touch responses of Arabidopsis. Plant Signal Behav, 2016. 11(6): p. e1187358 [PMID:27171129] Tsugama D,Liu S,Takano T The bZIP Protein VIP1 Is Involved in Touch Responses in Arabidopsis Roots. Plant Physiol., 2016. 171(2): p. 1355-65 [PMID:27208231] Takeo K,Ito T Subcellular localization of VIP1 is regulated by phosphorylation and 14-3-3 proteins. FEBS Lett., 2017. 591(13): p. 1972-1981 [PMID:28542772] Wang L,Lacroix B,Guo J,Citovsky V The Agrobacterium VirE2 effector interacts with multiple members of the Arabidopsis VIP1 protein family. Mol. Plant Pathol., 2018. 19(5): p. 1172-1183 [PMID:28802023]