PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID gw1.8.222.1
Common NameCHLNCDRAFT_11906
Organism
Chlorella variabilis NC64A
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Chlorophyta; Trebouxiophyceae; Chlorellales; Chlorellaceae; Chlorella
Family MYB
Protein Properties Length: 158aa    MW: 18974.7 Da    PI: 11.2772
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gw1.8.222.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding59.29.2e-19551148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     rg W+++Edell + v+q+G ++Wk+Ia+++   Rt+ qc +rwqk+l
      gw1.8.222.1  5 RGGWSKQEDELLRRMVAQYGAKNWKKIAEHFA-DRTDVQCLHRWQKVL 51
                     789*****************************.************986 PP
2Myb_DNA-binding61.91.3e-1957103148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      +g+WT++Ede ++++v+++G+  W+ Ia++++ gR +kqc++rw+++l
      gw1.8.222.1  57 KGPWTPDEDEAIIRLVALHGPQKWTMIAEYLP-GRIGKQCRERWHNHL 103
                      79******************************.*************97 PP
3Myb_DNA-binding49.41e-15109153147
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 
                      rg WT  Ede +v+ ++++G+  W++ a+++  gRt++ +k++w++ 
      gw1.8.222.1 109 RGQWTRHEDEVIVRFHRRFGNQ-WARMAQHLK-GRTDNAIKNHWNST 153
                      89******************99.********9.***********986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129420.793151IPR017930Myb domain
SMARTSM007172.7E-18453IPR001005SANT/Myb domain
PfamPF002495.4E-17551IPR001005SANT/Myb domain
SuperFamilySSF466891.94E-17661IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.8E-23758IPR009057Homeodomain-like
CDDcd001674.52E-14851No hitNo description
PROSITE profilePS5129432.62952107IPR017930Myb domain
SuperFamilySSF466899.36E-3154150IPR009057Homeodomain-like
SMARTSM007177.8E-1856105IPR001005SANT/Myb domain
PfamPF002491.9E-1857103IPR001005SANT/Myb domain
CDDcd001671.58E-1359103No hitNo description
Gene3DG3DSA:1.10.10.604.4E-2859107IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.5E-22108157IPR009057Homeodomain-like
SMARTSM007171.3E-13108156IPR001005SANT/Myb domain
PROSITE profilePS5129421.132108158IPR017930Myb domain
PfamPF002493.1E-13109153IPR001005SANT/Myb domain
CDDcd001671.44E-8112154No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032875Biological Processregulation of DNA endoreduplication
GO:0003677Molecular FunctionDNA binding
GO:0003713Molecular Functiontranscription coactivator activity
Sequence ? help Back to Top
Protein Sequence    Length: 158 aa     Download sequence    Send to blast
RRNGRGGWSK QEDELLRRMV AQYGAKNWKK IAEHFADRTD VQCLHRWQKV LNPEVHKGPW  60
TPDEDEAIIR LVALHGPQKW TMIAEYLPGR IGKQCRERWH NHLNPAIKRG QWTRHEDEVI  120
VRFHRRFGNQ WARMAQHLKG RTDNAIKNHW NSTLRRKV
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h88_C8e-7041585159MYB PROTO-ONCOGENE PROTEIN
1h89_C8e-7041585159MYB PROTO-ONCOGENE PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds 5'-AACGG-3' motifs in gene promoters (PubMed:21862669). Involved in the regulation of cytokinesis, probably via the activation of several G2/M phase-specific genes transcription (e.g. KNOLLE) (PubMed:17287251, PubMed:21862669, PubMed:25806785). Required for the maintenance of diploidy (PubMed:21862669). {ECO:0000269|PubMed:17287251, ECO:0000269|PubMed:21862669, ECO:0000269|PubMed:25806785}.; FUNCTION: Involved in transcription regulation during induced endoreduplication at the powdery mildew (e.g. G.orontii) infection site, thus promoting G.orontii growth and reproduction. {ECO:0000269|PubMed:20018666}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00505DAPTransfer from AT5G11510Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Slightly induced by salicylic acid (SA) (PubMed:16463103). Expressed in a cell cycle-dependent manner, with highest levels 2 hours before the peak of mitotic index in cells synchronized by aphidicolin. Activated by CYCB1 (PubMed:17287251). Accumulates at powdery mildew (e.g. G.orontii) infected cells. {ECO:0000269|PubMed:16463103, ECO:0000269|PubMed:17287251}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMap-Retrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_005848235.11e-114hypothetical protein CHLNCDRAFT_11906, partial
SwissprotQ94FL92e-71MB3R4_ARATH; Transcription factor MYB3R-4
TrEMBLE1ZCZ21e-113E1ZCZ2_CHLVA; Uncharacterized protein (Fragment)
STRINGXP_005848235.11e-114(Chlorella variabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
ChlorophytaeOGCP1516114
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G11510.24e-74myb domain protein 3r-4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Blanc G, et al.
    The Chlorella variabilis NC64A genome reveals adaptation to photosymbiosis, coevolution with viruses, and cryptic sex.
    Plant Cell, 2010. 22(9): p. 2943-55
    [PMID:20852019]
  3. Saito T, et al.
    Genetic interaction between G2/M phase-specific transcription factor MYB3R4 and MAPKKK ANP3 for execution of cytokinesis in Arabidopsis thaliana.
    Plant Signal Behav, 2015. 10(3): p. e990817
    [PMID:25806785]
  4. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  5. Chen P, et al.
    Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage.
    Nat Commun, 2017. 8(1): p. 635
    [PMID:28935922]