PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MELO3C009730P1

Organism

Cucumis melo

Taxonomic ID

3656

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

bZIP

Protein Properties

Length: 722aa MW: 78654.5 Da PI: 7.3609

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C009730P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	40	8.6e-13	221	282	2	63
XXXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 2 kelkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklksev 63 + kr r+++NRe+A+ sRqRKk ++eeLe+kv ++ + +L ++++ + e a l++++ MELO3C009730P1 221 DDEKRKARLMRNRESAQLSRQRKKHYVEELEDKVRNMHSTIAELNSKISYMMAENAGLRQQL 282 5679********************************************99999999888875 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00338	2.7E-17	220	284	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	10.611	222	282	IPR004827	Basic-leucine zipper domain
Pfam	PF00170	5.2E-11	223	282	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	3.75E-12	224	282	No hit	No description
Gene3D	G3DSA:1.20.5.170	1.9E-17	224	283	No hit	No description
CDD	cd14704	4.79E-22	225	276	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0042538	Biological Process	hyperosmotic salinity response
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005783	Cellular Component	endoplasmic reticulum
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 722 aa Download sequence Send to blast
MPDPFHLVSP SDQNPNSTSY ASEFDSLPIP PLDSLFFSDP NHDGPGDPFL YSTALDLGFD 60 ENDDFELTFD DLDDLCLPSE ADDFLISDNL DHPTNSPHLS PDVPLKDDSS VPLCSPAGSP 120 GSGSSAVSCQ QSPDDRGPAS SQGSGSGVSE GMNCPSSNAE CYDVIVDQKV KSEEVGKNCM 180 TKRKKEQDEG NGDFRSAKYQ RSSVSAEATN PQLGSCSINE DDEKRKARLM RNRESAQLSR 240 QRKKHYVEEL EDKVRNMHST IAELNSKISY MMAENAGLRQ QLSGSGMCQP PPPGMFPHPS 300 MPPMPPMPYS WMPCAPYVVK PQGSQVPLVP IPRLKPQQPI PVARGKKTES KKTEGRTKKA 360 ASVSFLGLLF FIMVFGGLVP LANDRFGNVG VVPGKLSFIG DNRLYNRNQG RVLRVDEHSN 420 LSDGVNVGTH CGKSGTLNRL QCERIYRKGR DLNFDQRGKE SQHLNDSDES VKLRNASEPL 480 VASLYVPRND KLVKIDGNLI IHSFLASEKA MASRRASDTD KARETGLAIP RDLSPALTIP 540 NIRALPSRPA NRDHKKATAV DGKLQQWFRE GLAGPMLSSG LCTEVFQFDV SSTAPGAIVP 600 ASSLVNTSRI HRKNGTHLNK GKNRRILGGL PVPLSRSNFN ITEEPARNPH KDNFPGNNNK 660 TASSMVVSVL IDPREAGDSE VDGVITPKSL SRIFVVVLLD SVKYVTYSCV LPRSGPHLVS 720 T*

Sequence ? help Back to Top

Protein Sequence Length: 722 aa Download sequence Send to blast

MPDPFHLVSP SDQNPNSTSY ASEFDSLPIP PLDSLFFSDP NHDGPGDPFL YSTALDLGFD  60
ENDDFELTFD DLDDLCLPSE ADDFLISDNL DHPTNSPHLS PDVPLKDDSS VPLCSPAGSP  120
GSGSSAVSCQ QSPDDRGPAS SQGSGSGVSE GMNCPSSNAE CYDVIVDQKV KSEEVGKNCM  180
TKRKKEQDEG NGDFRSAKYQ RSSVSAEATN PQLGSCSINE DDEKRKARLM RNRESAQLSR  240
QRKKHYVEEL EDKVRNMHST IAELNSKISY MMAENAGLRQ QLSGSGMCQP PPPGMFPHPS  300
MPPMPPMPYS WMPCAPYVVK PQGSQVPLVP IPRLKPQQPI PVARGKKTES KKTEGRTKKA  360
ASVSFLGLLF FIMVFGGLVP LANDRFGNVG VVPGKLSFIG DNRLYNRNQG RVLRVDEHSN  420
LSDGVNVGTH CGKSGTLNRL QCERIYRKGR DLNFDQRGKE SQHLNDSDES VKLRNASEPL  480
VASLYVPRND KLVKIDGNLI IHSFLASEKA MASRRASDTD KARETGLAIP RDLSPALTIP  540
NIRALPSRPA NRDHKKATAV DGKLQQWFRE GLAGPMLSSG LCTEVFQFDV SSTAPGAIVP  600
ASSLVNTSRI HRKNGTHLNK GKNRRILGGL PVPLSRSNFN ITEEPARNPH KDNFPGNNNK  660
TASSMVVSVL IDPREAGDSE VDGVITPKSL SRIFVVVLLD SVKYVTYSCV LPRSGPHLVS  720
T*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in salt and osmotic stress responses. Functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression of salt stress response genes (PubMed:17662035). Functions as a stress sensor and transducer in ER stress signaling pathway. ER stress induces proteolysis of BZIP17 by SBT6.1 (S1P) and S2P, and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones, as well as protein involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth (PubMed:20876872). {ECO:0000269\|PubMed:17662035, ECO:0000269\|PubMed:20876872}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681841	0.0	LN681841.1 Cucumis melo genomic scaffold, anchoredscaffold00011.
GenBank	LN713258	0.0	LN713258.1 Cucumis melo genomic chromosome, chr_4.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008443219.1	0.0	PREDICTED: bZIP transcription factor 17-like
Swissprot	O22208	1e-173	BZP17_ARATH; bZIP transcription factor 17
TrEMBL	A0A1S3B890	0.0	A0A1S3B890_CUCME; bZIP transcription factor 17-like
STRING	XP_008443219.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF7487	34	48

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G40950.1	1e-159	bZIP family protein

Publications ? help Back to Top
Zhou SF, et al. Membrane-associated transcription factor peptidase, site-2 protease, antagonizes ABA signaling in Arabidopsis. New Phytol., 2015. 208(1): p. 188-97 [PMID:25919792] Sagor GH, et al. The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis. Front Plant Sci, 2015. 6: p. 687 [PMID:26442007] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Kim JS,Yamaguchi-Shinozaki K,Shinozaki K ER-Anchored Transcription Factors bZIP17 and bZIP28 Regulate Root Elongation. Plant Physiol., 2018. 176(3): p. 2221-2230 [PMID:29367234] Cifuentes-Esquivel N, et al. bZIP17 regulates the expression of genes related to seed storage and germination, reducing seed susceptibility to osmotic stress. J. Cell. Biochem., 2018. 119(8): p. 6857-6868 [PMID:29693271] Guan P, et al. SENSITIVE TO SALT1, An Endoplasmic Reticulum-Localized Chaperone, Positively Regulates Salt Resistance. Plant Physiol., 2018. 178(3): p. 1390-1405 [PMID:30287478]