PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID C.cajan_12324
Common NameKK1_012700
Organism
Cajanus cajan
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Cajanus
Family bHLH
Protein Properties Length: 450aa    MW: 49019.5 Da    PI: 6.8007
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
C.cajan_12324genomeIIPGView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH38.91.5e-12272317454
                    HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
            HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                    +h e+Er+RR+++N++f  Lr ++P+       K++Ka+ L  A+ YI +L
  C.cajan_12324 272 NHVEAERQRREKLNQRFYALRAVVPNV-----SKMDKASLLGDAISYITEL 317
                    799***********************6.....5***************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142153.8E-22181IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088817.193268317IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000834.20E-15271322No hitNo description
SuperFamilySSF474597.46E-19271336IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.4E-19272337IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000104.7E-10272317IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.0E-16274323IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 450 aa     Download sequence    Send to blast
MTQSFVNGAG LPGQAFFNSA PVWVSGGDRL SASPCERARQ GQVFGLQTLV CIPSQNGVVE  60
LGSTELIYQN PDLTNKVKVL FNFSNNNLDV ASSWPATTTS ADQGENDPSS LWLNDPEVRD  120
SINTVAPTPS VSLPVNTQGI SKTIQLETSI QTPGSSTLTE TPSSIHAIPH NQSVFSRELN  180
FSEYAFDPKT GSNHNHHSLK PESGEILSFG ESKRTSYAAG VNGNSNSNSN SHFFSGHSPF  240
VAAADENNTT TTTNNNNGKR RKPANGREEP LNHVEAERQR REKLNQRFYA LRAVVPNVSK  300
MDKASLLGDA ISYITELKSK LQTLESDKDG LQKQLDGVKK ELEKATESVS LNHAVNSNNK  360
SSSNQALIDL DIDVKIIGWD AMIRIQCSKK NHPAARLMAA LMELDLDVHH ASVSVVNDLM  420
IQQATVKMGS RFYTQEQLRT ALSAKVGDVR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rqw_A1e-30183112194Transcription factor MYC3
4rqw_B1e-30183112194Transcription factor MYC3
4rs9_A1e-30183112194Transcription factor MYC3
4yz6_A1e-30183112194Transcription factor MYC3
5gnj_A7e-32266342278Transcription factor MYC2
5gnj_B7e-32266342278Transcription factor MYC2
5gnj_E7e-32266342278Transcription factor MYC2
5gnj_F7e-32266342278Transcription factor MYC2
5gnj_G7e-32266342278Transcription factor MYC2
5gnj_I7e-32266342278Transcription factor MYC2
5gnj_M7e-32266342278Transcription factor MYC2
5gnj_N7e-32266342278Transcription factor MYC2
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds to the G-box motif (5'-AACGTG-3') found in the promoter of the jasmonate-induced gene LAPA1 (PubMed:15231736). Acts as negative regulator of blue light-mediated photomorphogenesis and positively regulates root growth (PubMed:24483714). Promotes growth in response to the phytohormones abscisic acid (ABA) and jasmonate (JA) (PubMed:24483714). Binds to the G-box motif (5'-CACGTG-3') of the RBCS-3A gene promoter (PubMed:24483714). Acts downstream of the jasmonate (JA) receptor to orchestrate JA-mediated activation of plant responses (PubMed:28733419). Positively regulates both wound-responsive and pathogen-responsive genes through MYC2-targeted transcription factors (MTFs) involved in early response to JA (PubMed:28733419). With JA2L forms a transcription module that regulates wounding-responsive genes (PubMed:28733419). With ERF.C3 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). Plays a critical role in orchestrating JA-mediated defense gene expression during Botrytis cinerea infection (PubMed:28733419). Regulates negatively defense responses to root-knot nematodes, potentially by mediating crosstalk among the hormones strigolactones, abscisic acid (ABA) and jasmonate (JA) (PubMed:30576511). Regulates the termination of JA-mediated defense responses by specifically binding the G-box (5'-CACATG-3') motifs in the promoters of MTB1, MTB2 and MTB3, which are transcription factors that negatively regulates JA signaling (PubMed:30610166). May be involved in JA-induced chilling tolerance, possibly by ameliorating the antioxidant enzyme system of fruit and increasing proline and lycopene levels (PubMed:29528226). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:24483714, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:29528226, ECO:0000269|PubMed:30576511, ECO:0000269|PubMed:30610166}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapC.cajan_12324
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by methyl jasmonate (PubMed:15231736, PubMed:28733419). Induced by wounding (PubMed:15231736). Induced by infection with the fungal pathogen Botrytis cinerea (PubMed:28733419). Induced in fruit by storage in cold (PubMed:29528226). Induced by hydrogen peroxide and infection with root-knot nematodes (PubMed:30576511). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:29528226, ECO:0000269|PubMed:30576511}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020216494.10.0transcription factor MYC2
SwissprotA0A3Q7HRZ61e-161MYC2_SOLLC; Transcription factor MYC2
TrEMBLA0A151TH810.0A0A151TH81_CAJCA; Transcription factor MYC2
STRINGXP_007158304.10.0(Phaseolus vulgaris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF29383364
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32640.11e-132bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Gupta N,Prasad VB,Chattopadhyay S
    LeMYC2 acts as a negative regulator of blue light mediated photomorphogenic growth, and promotes the growth of adult tomato plants.
    BMC Plant Biol., 2014. 14: p. 38
    [PMID:24483714]
  3. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  4. Du M, et al.
    MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato.
    Plant Cell, 2017. 29(8): p. 1883-1906
    [PMID:28733419]
  5. Min D, et al.
    SlMYC2 Involved in Methyl Jasmonate-Induced Tomato Fruit Chilling Tolerance.
    J. Agric. Food Chem., 2018. 66(12): p. 3110-3117
    [PMID:29528226]
  6. Xu X, et al.
    Strigolactones positively regulate defense against root-knot nematodes in tomato.
    J. Exp. Bot., 2019. 70(4): p. 1325-1337
    [PMID:30576511]
  7. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]