PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Csa19g003230.2
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina
Family E2F/DP
Protein Properties Length: 349aa    MW: 39660.8 Da    PI: 9.5133
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Csa19g003230.2genomeCSGPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP40.44.8e-1345763871
         E2F_TDP 38 dvknkrRRiYDilNVLealnliekkekneirwkg 71
                     v  +rRRiYD++N+Le+++++++k kn ++wkg
  Csa19g003230.2 45 GV--ERRRIYDVVNILESIGIVARKGKNMYSWKG 76
                    56..9***************************98 PP

2E2F_TDP85.73.4e-27140220171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                     rkeksL+ll+q+f+k++ +s+++ +tl+++ak+L+s+     ++++k+RR+YDi+NV++++nliek     ++k+++rw g
  Csa19g003230.2 140 RKEKSLWLLSQNFVKMFLCSDDDLITLDSAAKALLSDsqdpvHMRTKVRRLYDIANVFSSMNLIEKtqipeTKKPAYRWLG 220
                     79********************************************************************99*******87 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.106.9E-141878IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.1E-142176IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.63E-103177IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023192.6E-104576IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.2E-22138222IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.9E-32140220IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.9E-20141220IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.81E-13142221IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 349 aa     Download sequence    Send to blast
MSSYAMVSQD AESLALQTYS RKEKSLGLLV SKVLTERNTY NFLAGVERRR IYDVVNILES  60
IGIVARKGKN MYSWKGFKEV PRSLDKLKEE GMREKLCISS TNNSDKVSDD VQREESSFSL  120
TPDDQETSSS SKIVSFADQR KEKSLWLLSQ NFVKMFLCSD DDLITLDSAA KALLSDSQDP  180
VHMRTKVRRL YDIANVFSSM NLIEKTQIPE TKKPAYRWLG SESIAETGTS LFNSDEPKKR  240
VFGTEITNLR AKRNKTDCSS NGKQIGYKKH DDANTEQESK PAASKYVFGP SFPTGASKKN  300
EYVRKGRLQE IESLASTYKP QYCNKEITSL LGHFTETWKR WYAELDRK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A9e-29202123228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapCsa19g003230.2
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010485503.10.0PREDICTED: E2F transcription factor-like E2FF
SwissprotQ8RWL00.0E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLR0HMF00.0R0HMF0_9BRAS; Uncharacterized protein
STRINGXP_010485503.10.0(Camelina sativa)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.10.0DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]