PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Csa01g011730.1

Organism

Camelina sativa

Taxonomic ID

90675

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

bZIP

Protein Properties

Length: 676aa MW: 73490.5 Da PI: 6.2205

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa01g011730.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	34.2	5.5e-11	193	237	3	47
XXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 3 elkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkk 47 ++k+ r ++NRe+A+ sRqRKk+++e Le+kvk+++a +L Csa01g011730.1 193 DDKKLLRQIRNRESAQLSRQRKKQQTEDLERKVKSMSATIADLNG 237 79**********************************998777765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00338	3.0E-11	191	255	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	9.657	193	253	IPR004827	Basic-leucine zipper domain
Pfam	PF00170	1.8E-9	194	252	IPR004827	Basic-leucine zipper domain
Gene3D	G3DSA:1.20.5.170	2.6E-12	195	253	No hit	No description
SuperFamily	SSF57959	1.75E-10	195	253	No hit	No description
CDD	cd14704	1.17E-16	196	246	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006990	Biological Process	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0009408	Biological Process	response to heat
GO:0005635	Cellular Component	nuclear envelope
GO:0005654	Cellular Component	nucleoplasm
GO:0005783	Cellular Component	endoplasmic reticulum
GO:0016020	Cellular Component	membrane
GO:0048471	Cellular Component	perinuclear region of cytoplasm
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 676 aa Download sequence Send to blast
MVTTESTSVI VPPPEIPNLN PYMFSESDLV SVPPLDPLFL SDSDPISMDA PISDLDFLLD 60 DENGDFADFD FPFDSSDDFF DFDLAEPAAA VIPEEIGNNR PNLDSSENRN GDGGSEGISD 120 SVHSQVSSQG SKTTFVNDTV DAALSSPESS NHQKSSVSKR KKEKEDSGGE YRSCKYQKSD 180 DKSVATNNEE DDDDKKLLRQ IRNRESAQLS RQRKKQQTED LERKVKSMSA TIADLNGKMA 240 YVMAENVALR QQMAIASGAP PPMNPYMAAP PLPYQWMPYP PYPVRGYGSQ TPLVPIPKLA 300 PKPVSSGRPR KTDSKKNEGK SKLKKVASIS FIGILFFVFL FGTLVPFMNV NYGGESGSFG 360 GLSKYDGHRY YNEHKGKVLM VGDGSDVRRE GGISDGNIHS SRRIHGDSDS CGGVDYNAHP 420 KVEGRPSSVR NVSDPLFASL FVPRNDGLVK IDGNLIIHSV LASEKATALA KKNVTETVKS 480 KERLTIPGAV SSALAVPEVR GNAAMLSQSS EGQRLHQWFH EGGSGTLMDY SMCTEVFQFD 540 IAPGAIVPSS VANISAEHLK NVTTHGKRIK NRRILEGLPV SLVASELNIT GTQTNKDTQN 600 KTFNGSTKNK PTSSSSMVVS VLLDPREIVD SETDRVVPPT QKSLSRIFVV VLLDSVKYVT 660 YSCVLPRSGL HLVAT*

Sequence ? help Back to Top

Protein Sequence Length: 676 aa Download sequence Send to blast

MVTTESTSVI VPPPEIPNLN PYMFSESDLV SVPPLDPLFL SDSDPISMDA PISDLDFLLD  60
DENGDFADFD FPFDSSDDFF DFDLAEPAAA VIPEEIGNNR PNLDSSENRN GDGGSEGISD  120
SVHSQVSSQG SKTTFVNDTV DAALSSPESS NHQKSSVSKR KKEKEDSGGE YRSCKYQKSD  180
DKSVATNNEE DDDDKKLLRQ IRNRESAQLS RQRKKQQTED LERKVKSMSA TIADLNGKMA  240
YVMAENVALR QQMAIASGAP PPMNPYMAAP PLPYQWMPYP PYPVRGYGSQ TPLVPIPKLA  300
PKPVSSGRPR KTDSKKNEGK SKLKKVASIS FIGILFFVFL FGTLVPFMNV NYGGESGSFG  360
GLSKYDGHRY YNEHKGKVLM VGDGSDVRRE GGISDGNIHS SRRIHGDSDS CGGVDYNAHP  420
KVEGRPSSVR NVSDPLFASL FVPRNDGLVK IDGNLIIHSV LASEKATALA KKNVTETVKS  480
KERLTIPGAV SSALAVPEVR GNAAMLSQSS EGQRLHQWFH EGGSGTLMDY SMCTEVFQFD  540
IAPGAIVPSS VANISAEHLK NVTTHGKRIK NRRILEGLPV SLVASELNIT GTQTNKDTQN  600
KTFNGSTKNK PTSSSSMVVS VLLDPREIVD SETDRVVPPT QKSLSRIFVV VLLDSVKYVT  660
YSCVLPRSGL HLVAT*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in ER stress responses. Functions as a stress sensor and transducer in ER stress signaling pathway. After proteolysis by SBT6.1 (S1P) and S2P, the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones (PubMed:18156219, PubMed:18634751, PubMed:18849477, PubMed:20876872). Following ER stress, activates proteins involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth (PubMed:20876872). {ECO:0000269\|PubMed:18156219, ECO:0000269\|PubMed:18634751, ECO:0000269\|PubMed:18849477, ECO:0000269\|PubMed:20876872}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00345	DAP	Transfer from AT3G10800	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa01g011730.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock. {ECO:0000269\|PubMed:18849477}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK226928	0.0	AK226928.1 Arabidopsis thaliana mRNA for bZIP transcription factor AtbZip28, complete cds, clone: RAFL09-25-P21.
GenBank	BT002502	0.0	BT002502.1 Arabidopsis thaliana putative bZIP transcription factor (At3g10800) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010492436.1	0.0	PREDICTED: bZIP transcription factor 28-like
Swissprot	Q9SG86	0.0	BZP28_ARATH; bZIP transcription factor 28
TrEMBL	D7L9R1	0.0	D7L9R1_ARALL; BZIP transcription factor family protein
STRING	XP_010492436.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM14397	18	22

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10800.1	0.0	bZIP family protein

Publications ? help Back to Top
Deng Y,Srivastava R,Howell SH Protein kinase and ribonuclease domains of IRE1 confer stress tolerance, vegetative growth, and reproductive development in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(48): p. 19633-8 [PMID:24145452] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Nagashima Y,Iwata Y,Ashida M,Mishiba K,Koizumi N Exogenous salicylic acid activates two signaling arms of the unfolded protein response in Arabidopsis. Plant Cell Physiol., 2014. 55(10): p. 1772-8 [PMID:25138441] Sun L,Zhang SS,Lu SJ,Liu JX Site-1 protease cleavage site is important for the ER stress-induced activation of membrane-associated transcription factor bZIP28 in Arabidopsis. Sci China Life Sci, 2015. 58(3): p. 270-5 [PMID:25634523] Zhang L,Chen H,Brandizzi F,Verchot J,Wang A The UPR branch IRE1-bZIP60 in plants plays an essential role in viral infection and is complementary to the only UPR pathway in yeast. PLoS Genet., 2015. 11(4): p. e1005164 [PMID:25875739] Ma ZX, et al. The THERMOSENSITIVE MALE STERILE 1 Interacts with the BiPs via DnaJ Domain and Stimulates Their ATPase Enzyme Activities in Arabidopsis. PLoS ONE, 2015. 10(7): p. e0132500 [PMID:26186593] Sagor GH, et al. The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis. Front Plant Sci, 2015. 6: p. 687 [PMID:26442007] Kørner CJ,Du X,Vollmer ME,Pajerowska-Mukhtar KM Endoplasmic Reticulum Stress Signaling in Plant Immunity--At the Crossroad of Life and Death. Int J Mol Sci, 2015. 16(11): p. 26582-98 [PMID:26556351] Zeng Y, et al. Unique COPII component AtSar1a/AtSec23a pair is required for the distinct function of protein ER export in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A., 2015. 112(46): p. 14360-5 [PMID:26578783] Meng Z,Ruberti C,Gong Z,Brandizzi F CPR5 modulates salicylic acid and the unfolded protein response to manage tradeoffs between plant growth and stress responses. Plant J., 2017. 89(3): p. 486-501 [PMID:27747970] Nawkar GM, et al. HY5, a positive regulator of light signaling, negatively controls the unfolded protein response in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(8): p. 2084-2089 [PMID:28167764] Iwata Y, et al. Activation of the Arabidopsis membrane-bound transcription factor bZIP28 is mediated by site-2 protease, but not site-1 protease. Plant J., 2017. 91(3): p. 408-415 [PMID:28407373] Zhang SS, et al. Tissue-Specific Transcriptomics Reveals an Important Role of the Unfolded Protein Response in Maintaining Fertility upon Heat Stress in Arabidopsis. Plant Cell, 2017. 29(5): p. 1007-1023 [PMID:28442596] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Kataoka R,Takahashi M,Suzuki N Coordination between bZIP28 and HSFA2 in the regulation of heat response signals in Arabidopsis. Plant Signal Behav, 2017. 12(11): p. e1376159 [PMID:28873003] Ruberti C,Lai Y,Brandizzi F Recovery from temporary endoplasmic reticulum stress in plants relies on the tissue-specific and largely independent roles of bZIP28 and bZIP60, as well as an antagonizing function of BAX-Inhibitor 1 upon the pro-adaptive signaling mediated by bZIP28. Plant J., 2018. 93(1): p. 155-165 [PMID:29124827] Kim JS,Yamaguchi-Shinozaki K,Shinozaki K ER-Anchored Transcription Factors bZIP17 and bZIP28 Regulate Root Elongation. Plant Physiol., 2018. 176(3): p. 2221-2230 [PMID:29367234]