PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Csa01g007130.1

Organism

Camelina sativa

Taxonomic ID

90675

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

bHLH

Protein Properties

Length: 203aa MW: 22850.6 Da PI: 9.8295

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa01g007130.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	37	6.2e-12	2	50	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h ++Er+RR+++N+ + Lr+l P + k+ + a+i ++e+Ik+Lq Csa01g007130.1 2 SHIAVERNRRRQMNEHLKSLRSLTPCF---YIKRGDQASIIGGVIEFIKELQ 50 89**********************9...9******************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	7.01E-12	1	54	No hit	No description
PROSITE profile	PS50888	14.684	1	49	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.83E-15	1	66	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	4.5E-9	2	50	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.4E-12	2	61	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.0E-11	4	55	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 203 aa Download sequence Send to blast
MSHIAVERNR RRQMNEHLKS LRSLTPCFYI KRGDQASIIG GVIEFIKELQ QLVQVLESKK 60 RRKTINRPSF PYDHQTIEPS ILAASTTRVP FSRIENVMTT STFKEVGACC NSPHANVEAK 120 ISGSNVVLRV VSRRIVGQLV KILSVLEKLS FQVLHLNISS MEETVLYFFV VKIGLECHLS 180 LEELTLEVQK SFVPEGIVVS TN*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	58	62	KKRRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Together with FMA and SPCH, regulates the stomata formation. Required for the differentiation of stomatal guard cells, by promoting successive asymmetric cell divisions and the formation of guard mother cells. Promotes the conversion of the leaf epidermis into stomata. {ECO:0000269\|PubMed:17183265, ECO:0000269\|PubMed:17183267}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa01g007130.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By UV, flagellin, and jasmonic acid (JA) treatments. {ECO:0000269\|PubMed:12679534}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF488580	0.0	AF488580.1 Arabidopsis thaliana clone bHLH045 putative bHLH transcription factor mRNA, partial sequence.
GenBank	DQ446639	0.0	DQ446639.1 Arabidopsis thaliana clone pENTR221-At3g06120 basic helix-loop-helix family protein (At3g06120) mRNA, complete cds.
GenBank	DQ653068	0.0	DQ653068.1 Arabidopsis thaliana clone 0000012753_0000009233 unknown mRNA.
GenBank	DQ863645	0.0	DQ863645.1 Arabidopsis thaliana helix-loop-helix protein (MUTE) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010436176.1	1e-145	PREDICTED: transcription factor MUTE
Swissprot	Q9M8K6	1e-140	MUTE_ARATH; Transcription factor MUTE
TrEMBL	A0A178VCY0	1e-138	A0A178VCY0_ARATH; MUTE
STRING	XP_010436176.1	1e-145	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM7073	26	40

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G06120.1	1e-142	bHLH family protein

Publications ? help Back to Top
Casson S,Gray JE Influence of environmental factors on stomatal development. New Phytol., 2008. 178(1): p. 9-23 [PMID:18266617] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Balcerowicz M,Ranjan A,Rupprecht L,Fiene G,Hoecker U Auxin represses stomatal development in dark-grown seedlings via Aux/IAA proteins. Development, 2014. 141(16): p. 3165-76 [PMID:25063454] de Marcos A, et al. Transcriptional profiles of Arabidopsis stomataless mutants reveal developmental and physiological features of life in the absence of stomata. Front Plant Sci, 2015. 6: p. 456 [PMID:26157447] Mahoney AK, et al. Functional analysis of the Arabidopsis thaliana MUTE promoter reveals a regulatory region sufficient for stomatal-lineage expression. Planta, 2016. 243(4): p. 987-98 [PMID:26748914] Klermund C, et al. LLM-Domain B-GATA Transcription Factors Promote Stomatal Development Downstream of Light Signaling Pathways in Arabidopsis thaliana Hypocotyls. Plant Cell, 2016. 28(3): p. 646-60 [PMID:26917680] Fu ZW,Wang YL,Lu YT,Yuan TT Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis. Plant Sci., 2016. 252: p. 282-289 [PMID:27717464] Qi X, et al. Autocrine regulation of stomatal differentiation potential by EPF1 and ERECTA-LIKE1 ligand-receptor signaling. Elife, 2018. [PMID:28266915] Raissig MT, et al. Mobile MUTE specifies subsidiary cells to build physiologically improved grass stomata. Science, 2017. 355(6330): p. 1215-1218 [PMID:28302860] Lee JH,Jung JH,Park CM Light Inhibits COP1-Mediated Degradation of ICE Transcription Factors to Induce Stomatal Development in Arabidopsis. Plant Cell, 2017. 29(11): p. 2817-2830 [PMID:29070509] Han SK, et al. MUTE Directly Orchestrates Cell-State Switch and the Single Symmetric Division to Create Stomata. Dev. Cell, 2018. 45(3): p. 303-315.e5 [PMID:29738710]