PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Bv4_096120_faoj.t1

Organism

Beta vulgaris

Taxonomic ID

161934

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Chenopodiaceae; Betoideae; Beta

Family

EIL

Protein Properties

Length: 698aa MW: 77321.5 Da PI: 5.4505

Description

EIL family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Bv4_096120_faoj.t1	genome	TBVR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	EIN3	520.7	6.2e-159	50	433	1	353
XXXXXXXXXXXXXXXXXXXXXXX..XXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS EIN3 1 eelkkrmwkdqmllkrlkerkkqlledkeaatgakksnksneqarrkkmsraQDgiLkYMlkemevcnaqGfvYgiipekgkpvegasdsL 91 +el++rmw+d+mllk+lke++k++ ke ++a+k+++s+eqarrkkmsraQDgiLkYMlk+mevc+aqGfvYgiipekgkpv+gasd+L Bv4_096120_faoj.t1 50 DELERRMWRDRMLLKKLKEQSKDKA--KEG-VDAAKQRQSQEQARRKKMSRAQDGILKYMLKMMEVCKAQGFVYGIIPEKGKPVSGASDNL 137 79*******************65..888.******************************************************** PP XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XX----STTS-HHHHHHHHHHHSSSSSS-TTS--TTT--HHHH---S--HHHH CS EIN3 92 raWWkekvefdrngpaaiskyqaknlilsgesslqtersseshslselqDTtlgSLLsalmqhcdppqrrfplekgvepPWWPtGkelwwg 182 raWWkekv+fdrngpaai+kyqa++ i++ ++++++ s++h+l+elqDTtlgSLLsalmqhcdppqrrfplekgv+pPWWPtG e+ww+ Bv4_096120_faoj.t1 138 RAWWKEKVRFDRNGPAAIAKYQADHSIPGINEDCNA-MASTPHTLQELQDTTLGSLLSALMQHCDPPQRRFPLEKGVPPPWWPTGIEEWWP 227 ******************************88.99************************************************ PP HHT--TT--.-----GGG--HHHHHHHHHHHHHHTGGGHHHHHHTTTTSSSSTTT--SHHHHHHHHHHTTTTT-S--XXXX..XXXXXXXX CS EIN3 183 elglskdqgtppykkphdlkkawkvsvLtavikhmsptieeirelerqskylqdkmsakesfallsvlnqeekecatvsah..ssslrkqs 271 +lgl+kdqg+ppykkphdlkkawkvsvLtavikhmsp+i++ir+l+rqsk+lqdkm+akes+++l+++nqee++++++ ++ ++ +s Bv4_096120_faoj.t1 228 QLGLPKDQGAPPYKKPHDLKKAWKVSVLTAVIKHMSPDIAKIRKLVRQSKCLQDKMTAKESATWLAIINQEEALARRLFPDrcPPPNAGGS 318 *****************************************************************************87667788 PP XXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX..................................XXXXXXXXXXXXXXXXXXXXX..... CS EIN3 272 pkvtlsceqkedvegkkeskikhvqavktta..................................gfpvvrkrkkkpsesakvsskevsrt 328 ++++s+++++dveg + ++v +k ++ + ++ +krk+++s s v+++++ Bv4_096120_faoj.t1 319 GSLVISDSSDYDVEGVDTDPNSEVDDNKPQNinlfnfgvgaerekfmtpnpmltsaikgevidanTSEFSEKRKQPSSGSHLVMDQKI-FV 408 ************766666699999999999****************************9999**99999999999986. PP .XXXXXXX.XXXXXXXXXXXXXXXX CS EIN3 329 cqssqfrgsetelifadknsisqne 353 c+ q+++s+++l+f d+ns+++++ Bv4_096120_faoj.t1 409 CEYPQCPYSDSRLGFLDRNSRNNHQ 433 ***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04873	9.1E-132	50	299	No hit	No description
Gene3D	G3DSA:1.10.3180.10	2.2E-75	172	309	IPR023278	Ethylene insensitive 3-like protein, DNA-binding domain
SuperFamily	SSF116768	1.96E-61	178	302	IPR023278	Ethylene insensitive 3-like protein, DNA-binding domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0001666	Biological Process	response to hypoxia
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0042742	Biological Process	defense response to bacterium
GO:0071281	Biological Process	cellular response to iron ion
GO:0005634	Cellular Component	nucleus
GO:0000976	Molecular Function	transcription regulatory region sequence-specific DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 698 aa Download sequence Send to blast
MGYFEDMGFC SNFDFFAPPP SMAGEGEVGR EAEAEAAVDE EYSDDEVDVD ELERRMWRDR 60 MLLKKLKEQS KDKAKEGVDA AKQRQSQEQA RRKKMSRAQD GILKYMLKMM EVCKAQGFVY 120 GIIPEKGKPV SGASDNLRAW WKEKVRFDRN GPAAIAKYQA DHSIPGINED CNAMASTPHT 180 LQELQDTTLG SLLSALMQHC DPPQRRFPLE KGVPPPWWPT GIEEWWPQLG LPKDQGAPPY 240 KKPHDLKKAW KVSVLTAVIK HMSPDIAKIR KLVRQSKCLQ DKMTAKESAT WLAIINQEEA 300 LARRLFPDRC PPPNAGGSGS LVISDSSDYD VEGVDTDPNS EVDDNKPQNI NLFNFGVGAE 360 REKFMTPNPM LTSAIKGEVI DANTSEFSEK RKQPSSGSHL VMDQKIFVCE YPQCPYSDSR 420 LGFLDRNSRN NHQLNCAYRF SPSTHGVGAT NFQGNSIEAA NFPTSFAQPE KLSLQSENQS 480 STTFSTSGLG LPEDGQKLIT NLMSVYDNTL HQNKNVNLGS GNFAENNQIG GGFACQQGAL 540 FGNSASQGMN INTMKDHNQA QPKVSQFQLD NGFLGQGMPM NVNNNPQQKL QFQMGSSVFQ 600 GTNMNPPEQK VQLAMDTSFN GQRTVSGANV VTQGTNMSGS VFQSNAIQLD HGRAFDSSSF 660 GMTLNDNMSD FGFGGVPFNL STIDFDQLSR QDNSIWNL

Sequence ? help Back to Top

Protein Sequence Length: 698 aa Download sequence Send to blast

MGYFEDMGFC SNFDFFAPPP SMAGEGEVGR EAEAEAAVDE EYSDDEVDVD ELERRMWRDR  60
MLLKKLKEQS KDKAKEGVDA AKQRQSQEQA RRKKMSRAQD GILKYMLKMM EVCKAQGFVY  120
GIIPEKGKPV SGASDNLRAW WKEKVRFDRN GPAAIAKYQA DHSIPGINED CNAMASTPHT  180
LQELQDTTLG SLLSALMQHC DPPQRRFPLE KGVPPPWWPT GIEEWWPQLG LPKDQGAPPY  240
KKPHDLKKAW KVSVLTAVIK HMSPDIAKIR KLVRQSKCLQ DKMTAKESAT WLAIINQEEA  300
LARRLFPDRC PPPNAGGSGS LVISDSSDYD VEGVDTDPNS EVDDNKPQNI NLFNFGVGAE  360
REKFMTPNPM LTSAIKGEVI DANTSEFSEK RKQPSSGSHL VMDQKIFVCE YPQCPYSDSR  420
LGFLDRNSRN NHQLNCAYRF SPSTHGVGAT NFQGNSIEAA NFPTSFAQPE KLSLQSENQS  480
STTFSTSGLG LPEDGQKLIT NLMSVYDNTL HQNKNVNLGS GNFAENNQIG GGFACQQGAL  540
FGNSASQGMN INTMKDHNQA QPKVSQFQLD NGFLGQGMPM NVNNNPQQKL QFQMGSSVFQ  600
GTNMNPPEQK VQLAMDTSFN GQRTVSGANV VTQGTNMSGS VFQSNAIQLD HGRAFDSSSF  660
GMTLNDNMSD FGFGGVPFNL STIDFDQLSR QDNSIWNL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4zds_A	4e-83	176	308	1	133	Protein ETHYLENE INSENSITIVE 3
4zds_B	4e-83	176	308	1	133	Protein ETHYLENE INSENSITIVE 3
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Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor acting as a positive regulator in the ethylene response pathway. Is required for ethylene responsiveness in adult plant tissues. Binds a primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter with consequence to activate the transcription of this gene. {ECO:0000269\|PubMed:9215635, ECO:0000269\|PubMed:9851977}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00367	DAP	Transfer from AT3G20770	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010694878.1	0.0	PREDICTED: ETHYLENE INSENSITIVE 3-like 1 protein
Swissprot	O24606	0.0	EIN3_ARATH; Protein ETHYLENE INSENSITIVE 3
TrEMBL	A0A0J8E4K4	0.0	A0A0J8E4K4_BETVU; Uncharacterized protein
STRING	XP_010694878.1	0.0	(Beta vulgaris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G20770.1	0.0	EIL family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Kim HG, et al. GDSL LIPASE1 modulates plant immunity through feedback regulation of ethylene signaling. Plant Physiol., 2013. 163(4): p. 1776-91 [PMID:24170202] Zhong S, et al. Ethylene-orchestrated circuitry coordinates a seedling's response to soil cover and etiolated growth. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(11): p. 3913-20 [PMID:24599595] Kim HG, et al. GDSL lipase 1 regulates ethylene signaling and ethylene-associated systemic immunity in Arabidopsis. FEBS Lett., 2014. 588(9): p. 1652-8 [PMID:24631536] Jourda C, et al. Expansion of banana (Musa acuminata) gene families involved in ethylene biosynthesis and signalling after lineage-specific whole-genome duplications. New Phytol., 2014. 202(3): p. 986-1000 [PMID:24716518] Zhang GB,Yi HY,Gong JM The Arabidopsis ethylene/jasmonic acid-NRT signaling module coordinates nitrate reallocation and the trade-off between growth and environmental adaptation. Plant Cell, 2014. 26(10): p. 3984-98 [PMID:25326291] Wang J, et al. Arabidopsis ROOT HAIR DEFECTIVE3 is involved in nitrogen starvation-induced anthocyanin accumulation. J Integr Plant Biol, 2015. 57(8): p. 708-21 [PMID:25494721] Ge XM, et al. Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis. Plant J., 2015. 82(1): p. 138-50 [PMID:25704455] Kazan K Diverse roles of jasmonates and ethylene in abiotic stress tolerance. Trends Plant Sci., 2015. 20(4): p. 219-29 [PMID:25731753] Yang C, et al. MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice. Plant Physiol., 2015. 169(1): p. 148-65 [PMID:25995326] Contreras-Cornejo HA, et al. Mitogen-Activated Protein Kinase 6 and Ethylene and Auxin Signaling Pathways Are Involved in Arabidopsis Root-System Architecture Alterations by Trichoderma atroviride. Mol. Plant Microbe Interact., 2015. 28(6): p. 701-10 [PMID:26067203] Li J,Xu HH,Liu WC,Zhang XW,Lu YT Ethylene Inhibits Root Elongation during Alkaline Stress through AUXIN1 and Associated Changes in Auxin Accumulation. Plant Physiol., 2015. 168(4): p. 1777-91 [PMID:26109425] Street IH, et al. Ethylene Inhibits Cell Proliferation of the Arabidopsis Root Meristem. Plant Physiol., 2015. 169(1): p. 338-50 [PMID:26149574] Ju C,Chang C Mechanistic Insights in Ethylene Perception and Signal Transduction. Plant Physiol., 2015. 169(1): p. 85-95 [PMID:26246449] Qing D, et al. Quantitative and Functional Phosphoproteomic Analysis Reveals that Ethylene Regulates Water Transport via the C-Terminal Phosphorylation of Aquaporin PIP2;1 in Arabidopsis. Mol Plant, 2016. 9(1): p. 158-174 [PMID:26476206] Zhang Y,Liu J,Chai J,Xing D Mitogen-activated protein kinase 6 mediates nuclear translocation of ORE3 to promote ORE9 gene expression in methyl jasmonate-induced leaf senescence. J. Exp. Bot., 2016. 67(1): p. 83-94 [PMID:26507893] Li X,Pan Y,Chang B,Wang Y,Tang Z NO Promotes Seed Germination and Seedling Growth Under High Salt May Depend on EIN3 Protein in Arabidopsis. Front Plant Sci, 2015. 6: p. 1203 [PMID:26779234] Yu Y, et al. Salt Stress and Ethylene Antagonistically Regulate Nucleocytoplasmic Partitioning of COP1 to Control Seed Germination. Plant Physiol., 2016. 170(4): p. 2340-50 [PMID:26850275] Pelagio-Flores R,Ruiz-Herrera LF,López-Bucio J Serotonin modulates Arabidopsis root growth via changes in reactive oxygen species and jasmonic acid-ethylene signaling. Physiol Plant, 2016. 158(1): p. 92-105 [PMID:26864878] Tao S, et al. The THO/TREX Complex Active in miRNA Biogenesis Negatively Regulates Root-Associated Acid Phosphatase Activity Induced by Phosphate Starvation. Plant Physiol., 2016. 171(4): p. 2841-53 [PMID:27329222] Song L, et al. The Molecular Mechanism of Ethylene-Mediated Root Hair Development Induced by Phosphate Starvation. PLoS Genet., 2016. 12(7): p. e1006194 [PMID:27427911] Jeong J, et al. Phytochrome and Ethylene Signaling Integration in Arabidopsis Occurs via the Transcriptional Regulation of Genes Co-targeted by PIFs and EIN3. Front Plant Sci, 2016. 7: p. 1055 [PMID:27486469] Tsai KJ,Lin CY,Ting CY,Shih MC Ethylene-Regulated Glutamate Dehydrogenase Fine-Tunes Metabolism during Anoxia-Reoxygenation. Plant Physiol., 2016. 172(3): p. 1548-1562 [PMID:27677986] Zhang F, et al. EIN2-dependent regulation of acetylation of histone H3K14 and non-canonical histone H3K23 in ethylene signalling. Nat Commun, 2016. 7: p. 13018 [PMID:27694846] Liu G, et al. Local Transcriptional Control of YUCCA Regulates Auxin Promoted Root-Growth Inhibition in Response to Aluminium Stress in Arabidopsis. PLoS Genet., 2016. 12(10): p. e1006360 [PMID:27716807] Shen X,Li Y,Pan Y,Zhong S Activation of HLS1 by Mechanical Stress via Ethylene-Stabilized EIN3 Is Crucial for Seedling Soil Emergence. Front Plant Sci, 2016. 7: p. 1571 [PMID:27822221] Shi H, et al. The Red Light Receptor Phytochrome B Directly Enhances Substrate-E3 Ligase Interactions to Attenuate Ethylene Responses. Dev. Cell, 2016. 39(5): p. 597-610 [PMID:27889482] Wawrzyńska A,Sirko A EIN3 interferes with the sulfur deficiency signaling in Arabidopsis thaliana through direct interaction with the SLIM1 transcription factor. Plant Sci., 2016. 253: p. 50-57 [PMID:27968996] Zemlyanskaya EV,Levitsky VG,Oshchepkov DY,Grosse I,Mironova VV The Interplay of Chromatin Landscape and DNA-Binding Context Suggests Distinct Modes of EIN3 Regulation in Arabidopsis thaliana. Front Plant Sci, 2016. 7: p. 2044 [PMID:28119721] He X,Jiang J,Wang CQ,Dehesh K ORA59 and EIN3 interaction couples jasmonate-ethylene synergistic action to antagonistic salicylic acid regulation of PDF expression. J Integr Plant Biol, 2017. 59(4): p. 275-287 [PMID:28168848] Abozeid A, et al. Ethylene Improves Root System Development under Cadmium Stress by Modulating Superoxide Anion Concentration in Arabidopsis thaliana. Front Plant Sci, 2017. 8: p. 253 [PMID:28286514] Quan R, et al. EIN3 and SOS2 synergistically modulate plant salt tolerance. Sci Rep, 2017. 7: p. 44637 [PMID:28300216] Kim GD,Cho YH,Yoo SD Regulatory Functions of Cellular Energy Sensor SNF1-Related Kinase1 for Leaf Senescence Delay through ETHYLENE- INSENSITIVE3 Repression. Sci Rep, 2017. 7(1): p. 3193 [PMID:28600557] Liu Y, et al. Light and Ethylene Coordinately Regulate the Phosphate Starvation Response through Transcriptional Regulation of PHOSPHATE STARVATION RESPONSE1. Plant Cell, 2017. 29(9): p. 2269-2284 [PMID:28842534] Liu X,Li Y,Zhong S Interplay between Light and Plant Hormones in the Control of Arabidopsis Seedling Chlorophyll Biosynthesis. Front Plant Sci, 2017. 8: p. 1433 [PMID:28861105] Zhang F, et al. EIN2 mediates direct regulation of histone acetylation in the ethylene response. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(38): p. 10274-10279 [PMID:28874528] Yan Z, et al. Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1. Plant Physiol., 2017. 175(3): p. 1438-1454 [PMID:28931628] Liu X, et al. EIN3 and PIF3 Form an Interdependent Module That Represses Chloroplast Development in Buried Seedlings. Plant Cell, 2017. 29(12): p. 3051-3067 [PMID:29114016] Feng Y, et al. Ethylene promotes root hair growth through coordinated EIN3/EIL1 and RHD6/RSL1 activity in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(52): p. 13834-13839 [PMID:29233944] Harkey AF, et al. Identification of Transcriptional and Receptor Networks That Control Root Responses to Ethylene. Plant Physiol., 2018. 176(3): p. 2095-2118 [PMID:29259106] Zhang F,Wang L,Ko EE,Shao K,Qiao H Histone Deacetylases SRT1 and SRT2 Interact with ENAP1 to Mediate Ethylene-Induced Transcriptional Repression. Plant Cell, 2018. 30(1): p. 153-166 [PMID:29298835] Lv B, et al. Brassinosteroids regulate root growth by controlling reactive oxygen species homeostasis and dual effect on ethylene synthesis in Arabidopsis. PLoS Genet., 2018. 14(1): p. e1007144 [PMID:29324765] Dou L,He K,Higaki T,Wang X,Mao T Ethylene Signaling Modulates Cortical Microtubule Reassembly in Response to Salt Stress. Plant Physiol., 2018. 176(3): p. 2071-2081 [PMID:29431630] Meng LS,Xu MK,Wan W,Wang JY Integration of Environmental and Developmental (or Metabolic) Control of Seed Mass by Sugar and Ethylene Metabolisms in Arabidopsis. J. Agric. Food Chem., 2018. 66(13): p. 3477-3488 [PMID:29528636] Munné-Bosch S,Simancas B,Müller M Ethylene signaling cross-talk with other hormones in Arabidopsis thaliana exposed to contrasting phosphate availability: Differential effects in roots, leaves and fruits. J. Plant Physiol., 2018. 226: p. 114-122 [PMID:29758376]