PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Bostr.18473s0108.1.p | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Boechereae; Boechera
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Family | C2H2 | ||||||||
Protein Properties | Length: 135aa MW: 15676.2 Da PI: 10.2303 | ||||||||
Description | C2H2 family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | zf-C2H2 | 11.6 | 0.00088 | 71 | 94 | 2 | 23 |
EET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCp..dCgksFsrksnLkrHirtH 23 kCp C+++F+ + + Hir+H Bostr.18473s0108.1.p 71 KCPwkGCKMTFKWAWSRTEHIRVH 94 79********************99 PP | |||||||
2 | zf-C2H2 | 16 | 3.3e-05 | 100 | 126 | 1 | 23 |
EEET..TTTEEESSHHHHHHHHHH..T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt..H 23 y+C Cg++F+ s++ rH r+ H Bostr.18473s0108.1.p 100 YVCAepGCGQTFRFVSDFSRHKRKtgH 126 899999*****************9777 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
SMART | SM00545 | 4.0E-15 | 19 | 60 | IPR003349 | JmjN domain |
PROSITE profile | PS51183 | 13.883 | 20 | 61 | IPR003349 | JmjN domain |
Pfam | PF02375 | 3.5E-15 | 21 | 54 | IPR003349 | JmjN domain |
SuperFamily | SSF57667 | 4.75E-15 | 55 | 105 | No hit | No description |
Gene3D | G3DSA:3.30.160.60 | 4.3E-10 | 68 | 93 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
SMART | SM00355 | 0.0015 | 70 | 94 | IPR015880 | Zinc finger, C2H2-like |
PROSITE profile | PS50157 | 10.928 | 70 | 99 | IPR007087 | Zinc finger, C2H2 |
PROSITE pattern | PS00028 | 0 | 72 | 94 | IPR007087 | Zinc finger, C2H2 |
Gene3D | G3DSA:3.30.160.60 | 6.7E-11 | 94 | 123 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
SuperFamily | SSF57667 | 9.18E-5 | 98 | 122 | No hit | No description |
SMART | SM00355 | 0.62 | 100 | 126 | IPR015880 | Zinc finger, C2H2-like |
PROSITE profile | PS50157 | 11.032 | 100 | 131 | IPR007087 | Zinc finger, C2H2 |
PROSITE pattern | PS00028 | 0 | 102 | 126 | IPR007087 | Zinc finger, C2H2 |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0003676 | Molecular Function | nucleic acid binding | ||||
GO:0046872 | Molecular Function | metal ion binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 135 aa Download sequence Send to blast |
MAVSEQSQDV FPWLKSLPVA PEFRPTLAEF QDPIAYIFKI EEEASRYGIC KILPPYLVQH 60 QRVHSDDRPL KCPWKGCKMT FKWAWSRTEH IRVHTGARPY VCAEPGCGQT FRFVSDFSRH 120 KRKTGHSVKK TKKR* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
6a57_A | 5e-53 | 56 | 134 | 62 | 140 | Lysine-specific demethylase REF6 |
6a58_A | 5e-53 | 56 | 134 | 62 | 140 | Lysine-specific demethylase REF6 |
6a59_A | 5e-53 | 56 | 134 | 62 | 140 | Lysine-specific demethylase REF6 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Histone demethylase that demethylates 'Lys-27' (H3K27me) of histone H3. Demethylates both tri- (H3K27me3) and di-methylated (H3K27me2) H3K27me (PubMed:21642989, PubMed:27111035). Demethylates also H3K4me3/2 and H3K36me3/2 in an in vitro assay (PubMed:20711170). Involved in the transcriptional regulation of hundreds of genes regulating developmental patterning and responses to various stimuli (PubMed:18467490). Binds DNA via its four zinc fingers in a sequence-specific manner, 5'-CTCTGYTY-3', to promote the demethylation of H3K27me3 and the regulation of organ boundary formation (PubMed:27111034, PubMed:27111035). Involved in the regulation of flowering time by repressing FLOWERING LOCUS C (FLC) expression (PubMed:15377760). Interacts with the NF-Y complexe to regulate SOC1 (PubMed:25105952). Mediates the recruitment of BRM to its target loci (PubMed:27111034). {ECO:0000269|PubMed:15377760, ECO:0000269|PubMed:18467490, ECO:0000269|PubMed:20711170, ECO:0000269|PubMed:21642989, ECO:0000269|PubMed:25105952, ECO:0000269|PubMed:27111034, ECO:0000269|PubMed:27111035}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Bostr.18473s0108.1.p |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | AL049659 | 4e-99 | AL049659.2 Arabidopsis thaliana DNA chromosome 3, BAC clone T29H11. | |||
GenBank | AY664499 | 4e-99 | AY664499.1 Arabidopsis thaliana relative of early flowering 6 (REF6) mRNA, complete cds. | |||
GenBank | CP002686 | 4e-99 | CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_002875902.1 | 2e-50 | lysine-specific demethylase REF6 isoform X2 | ||||
Refseq | XP_010503472.1 | 2e-50 | PREDICTED: lysine-specific demethylase REF6-like | ||||
Swissprot | Q9STM3 | 6e-50 | REF6_ARATH; Lysine-specific demethylase REF6 | ||||
TrEMBL | D7LRW5 | 4e-49 | D7LRW5_ARALL; Uncharacterized protein | ||||
STRING | Bostr.18473s0108.1.p | 2e-96 | (Boechera stricta) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48430.1 | 2e-52 | relative of early flowering 6 |
Link Out ? help Back to Top | |
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Phytozome | Bostr.18473s0108.1.p |