PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Brast08G245500.1.p
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Brachypodieae; Brachypodium
Family C2H2
Protein Properties Length: 398aa    MW: 44477.4 Da    PI: 8.1776
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Brast08G245500.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2110.001396118323
                         ET..TTTEEESSHHHHHHHHHHT CS
             zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                         C+  +Cgk+F +   L++H  +H
  Brast08G245500.1.p  96 CSyeNCGKTFVDVAALRKHAHVH 118
                         77779**************9887 PP

2zf-C2H220.21.6e-06123147123
                         EEET..TTTEEESSHHHHHHHHHHT CS
             zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                         y Cp   Cgk F ++s LkrH  tH
  Brast08G245500.1.p 123 YICPepGCGKKFVDSSKLKRHNLTH 147
                         89*******************9998 PP

3zf-C2H218.45.8e-06153177123
                         EEET..TTTEEESSHHHHHHHHHHT CS
             zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                         + Cp   Cgk Fs   nL+ H++tH
  Brast08G245500.1.p 153 FICPhpGCGKAFSLDFNLRAHLKTH 177
                         789*********************9 PP

4zf-C2H212.30.00051183207123
                         EEET..TTTEEESSHHHHHHHHHHT CS
             zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                         ++Cp   Cgk+F++ + Lk H + H
  Brast08G245500.1.p 183 HVCPfpACGKRFTSDYKLKCHVKAH 207
                         789999****************988 PP

5zf-C2H213.30.00025253278123
                         EEET..TTTEEESSHHHHHHHHHH.T CS
             zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                         y+Cp   Cgk + + + L+ H +t H
  Brast08G245500.1.p 253 YVCPyeGCGKAYIHGYKLNLHFKTqH 278
                         99********************9988 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.602.2E-1290120IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.09494123IPR007087Zinc finger, C2H2
SMARTSM003550.01694118IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028096118IPR007087Zinc finger, C2H2
SuperFamilySSF576671.38E-897147No hitNo description
Gene3DG3DSA:3.30.160.601.1E-13121143IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003555.2E-4123147IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015713.838123152IPR007087Zinc finger, C2H2
PROSITE patternPS000280125147IPR007087Zinc finger, C2H2
SuperFamilySSF576671.88E-12134186No hitNo description
Gene3DG3DSA:3.30.160.604.1E-18144178IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0014153177IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.759153182IPR007087Zinc finger, C2H2
PROSITE patternPS000280155177IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.5E-7180208IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.827183212IPR007087Zinc finger, C2H2
SMARTSM003550.16183207IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280185207IPR007087Zinc finger, C2H2
SuperFamilySSF576678.41E-6248278No hitNo description
Gene3DG3DSA:3.30.160.601.1E-8249278IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.785253286IPR007087Zinc finger, C2H2
SMARTSM003550.023253278IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280255278IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 398 aa     Download sequence    Send to blast
MEYAAAGSGG YYYYQPPHPH QQPQPQTQTL RRRPRPAARW VKQWIPQDLA SPGANCALFK  60
WVREDVYRNL KENPNGPEPE TQARKPEPAT EILFLCSYEN CGKTFVDVAA LRKHAHVHGE  120
RQYICPEPGC GKKFVDSSKL KRHNLTHTGQ KDFICPHPGC GKAFSLDFNL RAHLKTHALE  180
NYHVCPFPAC GKRFTSDYKL KCHVKAHEKT GSPVAVQHTP PAEKPQNIIK PSTQAAPKPS  240
PPVPATFSAD RPYVCPYEGC GKAYIHGYKL NLHFKTQHPE HSQEESGRPA APPGEYAGNQ  300
YSYAEVGEHH APNPKRSKTN PAHKAVPPSK PYNVKISSRM SADTSGVKNQ WPGKGMYNDD  360
SEETEEDHGG NNNNNVQEGW RYGNQNADDE ETEEDES*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C1e-33962098119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapBrast08G245500.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003569122.10.0zinc finger transcription factor YY1
SwissprotQ2V3L31e-100YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLI1HN530.0I1HN53_BRADI; Uncharacterized protein
STRINGBRADI2G39700.10.0(Brachypodium distachyon)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP20943899
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-101C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]