PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009147417.1
Organism
Brassica rapa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
Family E2F/DP
Protein Properties Length: 358aa    MW: 40542.4 Da    PI: 7.6132
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009147417.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP65.28.6e-212388171
         E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                    rkeksL++l ++f++++++ + +   ++e+a +L    v  +rRRiYD++N+Le+++++++k kn ++w+g
  XP_009147417.1 23 RKEKSLGVLVSNFVRIYNRDDVDLFGIDEAAAKL---GV--ERRRIYDVVNILESIEVVSRKGKNLYSWNG 88
                    79*****************999************...**..****************************98 PP
2E2F_TDP82.92.6e-26148228171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                     +ke+sL+ll+q+f+k++ +s+++ +tl+++ak+L+s+     ++++k+RR+YDi+NVL++++liek     ++k++++w g
  XP_009147417.1 148 KKESSLWLLSQNFVKMFLCSHDDLITLDSAAKALLSDsqdpmHMRTKVRRLYDIANVLSSMELIEKthipgTRKPAYKWLG 228
                     689****************************************************************************87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.2E-222089IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467858.5E-152286IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.6E-242388IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.7E-172488IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.108.4E-22146230IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.7E-30148228IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.7E-20149228IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467859.07E-13151229IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 358 aa     Download sequence    Send to blast
MEKMPWIVSS QDVDALALQS YSRKEKSLGV LVSNFVRIYN RDDVDLFGID EAAAKLGVER  60
RRIYDVVNIL ESIEVVSRKG KNLYSWNGFL HIPRSLHHLK EEGLREGFGT SSICSNSDKV  120
SHDDESEESL CLTPDDQDNS SLSKLDHKKE SSLWLLSQNF VKMFLCSHDD LITLDSAAKA  180
LLSDSQDPMH MRTKVRRLYD IANVLSSMEL IEKTHIPGTR KPAYKWLGSK SLTEKGSTLF  240
NSTNESKKRV FGTEITNFST KRNKTDCSSN YVQNGYNKHD EEEKKPAAKT YVFGPFSPTG  300
ASKKNNNNNA GTNNSGRLQD LEALSSTYKP QYCNQDVTGL LGHYTEAWNK WFAELDRK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A1e-31222203228Transcription factor E2F8
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in mid-S phase. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:15308755}.
UniprotTISSUE SPECIFICITY: High expression in young cotyledons and leaves, hypocotyls, shoot apical meristem, roots and mature pollen grains, moderate in developing trichomes, flowers and at early stages of developing anthers, and barely detectable in mature leaves. Not detected in primary root meristem, emerging lateral roots, pistils, developing embryos and siliques. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_009147417.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009147417.10.0PREDICTED: E2F transcription factor-like E2FF
RefseqXP_013674749.10.0E2F transcription factor-like E2FF
SwissprotQ8RWL00.0E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLA0A397ZIC50.0A0A397ZIC5_BRACM; Uncharacterized protein
TrEMBLM4FDF60.0M4FDF6_BRARP; Uncharacterized protein
STRINGBra039127.1-P0.0(Brassica rapa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.11e-179DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]