PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | XP_013587510.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
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Family | E2F/DP | ||||||||
Protein Properties | Length: 358aa MW: 40455.4 Da PI: 7.9906 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 65.2 | 8.6e-21 | 23 | 88 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rkeksL++l ++f++++++ + + ++e+a +L v +rRRiYD++N+Le+++++++k kn ++w+g XP_013587510.1 23 RKEKSLGVLVSNFVRIYNRDDVDLFGIDEAAAKL---GV--ERRRIYDVVNILESIEVVSRKGKNLYSWNG 88 79*****************999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 82.9 | 2.6e-26 | 148 | 228 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 +ke+sL+ll+q+f+k++ +s+++ +tl+++ak+L+s+ ++++k+RR+YDi+NVL++++liek ++k++++w g XP_013587510.1 148 KKESSLWLLSQNFVKMFLCSHDDLITLDSAAKALLSDsqdpmHMRTKVRRLYDIANVLSSMELIEKthipgTRKPAYKWLG 228 689****************************************************************************87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 2.2E-22 | 20 | 89 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 8.5E-15 | 22 | 86 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 3.6E-24 | 23 | 88 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 2.7E-17 | 24 | 88 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 8.4E-22 | 146 | 230 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.7E-30 | 148 | 228 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 8.7E-20 | 149 | 228 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 9.07E-13 | 151 | 229 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005737 | Cellular Component | cytoplasm | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 358 aa Download sequence Send to blast |
MEKMPWIVSS QDVDALALQS YSRKEKSLGV LVSNFVRIYN RDDVDLFGID EAAAKLGVER 60 RRIYDVVNIL ESIEVVSRKG KNLYSWNGFL HIPRSLHQLK EEGLREGFGT SSICSNSDKV 120 SHDDESEESF SLTPDDQDNS SLSKLDHKKE SSLWLLSQNF VKMFLCSHDD LITLDSAAKA 180 LLSDSQDPMH MRTKVRRLYD IANVLSSMEL IEKTHIPGTR KPAYKWLGSK SLTEKGSSLF 240 NSPNESKKRV FGTEITNLST KRNKTDCSSN YVQNGYKKHD EEEKKPAAKS YVFGPFSPTA 300 ASKKNNINNA GTSNSGRLQD LEALSSAYKP QYCNQDVTGL LGHYTEAWNK WFAELDRK |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 2e-32 | 22 | 220 | 3 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in mid-S phase. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:15308755}. | |||||
Uniprot | TISSUE SPECIFICITY: High expression in young cotyledons and leaves, hypocotyls, shoot apical meristem, roots and mature pollen grains, moderate in developing trichomes, flowers and at early stages of developing anthers, and barely detectable in mature leaves. Not detected in primary root meristem, emerging lateral roots, pistils, developing embryos and siliques. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | XP_013587510.1 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_013587510.1 | 0.0 | PREDICTED: E2F transcription factor-like E2FF | ||||
Swissprot | Q8RWL0 | 0.0 | E2FF_ARATH; E2F transcription factor-like E2FF | ||||
TrEMBL | A0A0D3CNF0 | 0.0 | A0A0D3CNF0_BRAOL; Uncharacterized protein | ||||
TrEMBL | A0A3P6ERE5 | 0.0 | A0A3P6ERE5_BRAOL; Uncharacterized protein | ||||
STRING | Bo5g155250.1 | 0.0 | (Brassica oleracea) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM6003 | 25 | 47 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G01330.1 | 0.0 | DP-E2F-like protein 3 |
Publications ? help Back to Top | |||
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