PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

GSBRNA2T00060242001

Common Name

GSBRNA2T00060242001

Organism

Brassica napus

Taxonomic ID

3708

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

bZIP

Protein Properties

Length: 636aa MW: 69092.9 Da PI: 6.065

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
GSBRNA2T00060242001	genome	Genoscope	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	40.8	4.7e-13	187	248	2	63
XXXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 2 kelkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklksev 63 + k+ r+++NRe+A+ sR+RKk+++eeL+ kvk++ + +L +++ e a+l+++ GSBRNA2T00060242001 187 DDEKKKVRLIRNRESAQLSRLRKKQYVEELQGKVKTMNSTIAELNGKISYVMAENAALRQQM 248 56799******************************************999999999999876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.20.5.170	4.5E-16	179	250	No hit	No description
SMART	SM00338	2.4E-16	186	250	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	10.048	188	251	IPR004827	Basic-leucine zipper domain
Pfam	PF00170	1.6E-10	189	248	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	7.5E-12	190	248	No hit	No description
CDD	cd14704	1.35E-17	191	242	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0016021	Cellular Component	integral component of membrane
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 636 aa Download sequence Send to blast
MTESTFSIAN PPEMPDLNPN TLPDPEMISV PPLDPLFLSA SDPISDLSFF FNDENGDFAD 60 LDFSFDDSVD FVDFDLDAEP PVAISEELGS SGDQSPEAIA NHANLDSPEE KIVDRGLEDR 120 SDSVHSQVSS QGSKTSGGCD TLSSPENSSV SKSKSTSKRK KGDSGGDYRS FKYQKSDEKS 180 ASPVEEDDEK KKVRLIRNRE SAQLSRLRKK QYVEELQGKV KTMNSTIAEL NGKISYVMAE 240 NAALRQQMMA AAGGGAPPPM NPYMAAPPLP YQWMPYPPPP YPYGSQIPIP KLPLPSCSRP 300 KKGEGKSKLK KAASISFIGI MFFMFLFGTL VPFMNVDNGG DSGLAKYEGR RYYDEHRGKV 360 LMVGDGSDVR RESVCSGRDS CGGVEGRVGN SSEPLFASLY VPRNNGLVKI DGNLIIHSVL 420 ASEKAKKNIS ETIKSKEAEL TVPGVPVPDV RGNGAMLPHS SKALSSSGSP DGKRLHQWFH 480 EGGAGTLMDY SMCTEVFQFD ISPGAIVPSS VSNITREHLQ NVTTTRDKRM KNRRILEGLP 540 VSRLASELNI TEAQASKDAQ NKTFHGKANT KPTSSSMVVS VLLDPREVVD SETDRVMPSN 600 PKSLSRVFVV VLLDSVKYVT YSCVLPRSGL HLVAT*

Sequence ? help Back to Top

Protein Sequence Length: 636 aa Download sequence Send to blast

MTESTFSIAN PPEMPDLNPN TLPDPEMISV PPLDPLFLSA SDPISDLSFF FNDENGDFAD  60
LDFSFDDSVD FVDFDLDAEP PVAISEELGS SGDQSPEAIA NHANLDSPEE KIVDRGLEDR  120
SDSVHSQVSS QGSKTSGGCD TLSSPENSSV SKSKSTSKRK KGDSGGDYRS FKYQKSDEKS  180
ASPVEEDDEK KKVRLIRNRE SAQLSRLRKK QYVEELQGKV KTMNSTIAEL NGKISYVMAE  240
NAALRQQMMA AAGGGAPPPM NPYMAAPPLP YQWMPYPPPP YPYGSQIPIP KLPLPSCSRP  300
KKGEGKSKLK KAASISFIGI MFFMFLFGTL VPFMNVDNGG DSGLAKYEGR RYYDEHRGKV  360
LMVGDGSDVR RESVCSGRDS CGGVEGRVGN SSEPLFASLY VPRNNGLVKI DGNLIIHSVL  420
ASEKAKKNIS ETIKSKEAEL TVPGVPVPDV RGNGAMLPHS SKALSSSGSP DGKRLHQWFH  480
EGGAGTLMDY SMCTEVFQFD ISPGAIVPSS VSNITREHLQ NVTTTRDKRM KNRRILEGLP  540
VSRLASELNI TEAQASKDAQ NKTFHGKANT KPTSSSMVVS VLLDPREVVD SETDRVMPSN  600
PKSLSRVFVV VLLDSVKYVT YSCVLPRSGL HLVAT*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in ER stress responses. Functions as a stress sensor and transducer in ER stress signaling pathway. After proteolysis by SBT6.1 (S1P) and S2P, the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones (PubMed:18156219, PubMed:18634751, PubMed:18849477, PubMed:20876872). Following ER stress, activates proteins involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth (PubMed:20876872). {ECO:0000269\|PubMed:18156219, ECO:0000269\|PubMed:18634751, ECO:0000269\|PubMed:18849477, ECO:0000269\|PubMed:20876872}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	GSBRNA2T00060242001

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock. {ECO:0000269\|PubMed:18849477}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK353117	1e-179	AK353117.1 Thellungiella halophila mRNA, complete cds, clone: RTFL01-21-B04.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009122597.1	0.0	PREDICTED: bZIP transcription factor 28
Swissprot	Q9SG86	0.0	BZP28_ARATH; bZIP transcription factor 28
TrEMBL	A0A078HET2	0.0	A0A078HET2_BRANA; BnaA01g31420D protein
STRING	Bra034147.1-P	0.0	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM14397	18	22

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10800.1	1e-141	bZIP family protein

Publications ? help Back to Top
Deng Y,Srivastava R,Howell SH Protein kinase and ribonuclease domains of IRE1 confer stress tolerance, vegetative growth, and reproductive development in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(48): p. 19633-8 [PMID:24145452] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Nagashima Y,Iwata Y,Ashida M,Mishiba K,Koizumi N Exogenous salicylic acid activates two signaling arms of the unfolded protein response in Arabidopsis. Plant Cell Physiol., 2014. 55(10): p. 1772-8 [PMID:25138441] Chalhoub B, et al. Plant genetics. Early allopolyploid evolution in the post-Neolithic Brassica napus oilseed genome. Science, 2014. 345(6199): p. 950-3 [PMID:25146293] Sun L,Zhang SS,Lu SJ,Liu JX Site-1 protease cleavage site is important for the ER stress-induced activation of membrane-associated transcription factor bZIP28 in Arabidopsis. Sci China Life Sci, 2015. 58(3): p. 270-5 [PMID:25634523] Zhang L,Chen H,Brandizzi F,Verchot J,Wang A The UPR branch IRE1-bZIP60 in plants plays an essential role in viral infection and is complementary to the only UPR pathway in yeast. PLoS Genet., 2015. 11(4): p. e1005164 [PMID:25875739] Ma ZX, et al. The THERMOSENSITIVE MALE STERILE 1 Interacts with the BiPs via DnaJ Domain and Stimulates Their ATPase Enzyme Activities in Arabidopsis. PLoS ONE, 2015. 10(7): p. e0132500 [PMID:26186593] Sagor GH, et al. The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis. Front Plant Sci, 2015. 6: p. 687 [PMID:26442007] Kørner CJ,Du X,Vollmer ME,Pajerowska-Mukhtar KM Endoplasmic Reticulum Stress Signaling in Plant Immunity--At the Crossroad of Life and Death. Int J Mol Sci, 2015. 16(11): p. 26582-98 [PMID:26556351] Zeng Y, et al. Unique COPII component AtSar1a/AtSec23a pair is required for the distinct function of protein ER export in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A., 2015. 112(46): p. 14360-5 [PMID:26578783] Meng Z,Ruberti C,Gong Z,Brandizzi F CPR5 modulates salicylic acid and the unfolded protein response to manage tradeoffs between plant growth and stress responses. Plant J., 2017. 89(3): p. 486-501 [PMID:27747970] Nawkar GM, et al. HY5, a positive regulator of light signaling, negatively controls the unfolded protein response in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(8): p. 2084-2089 [PMID:28167764] Iwata Y, et al. Activation of the Arabidopsis membrane-bound transcription factor bZIP28 is mediated by site-2 protease, but not site-1 protease. Plant J., 2017. 91(3): p. 408-415 [PMID:28407373] Zhang SS, et al. Tissue-Specific Transcriptomics Reveals an Important Role of the Unfolded Protein Response in Maintaining Fertility upon Heat Stress in Arabidopsis. Plant Cell, 2017. 29(5): p. 1007-1023 [PMID:28442596] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Kataoka R,Takahashi M,Suzuki N Coordination between bZIP28 and HSFA2 in the regulation of heat response signals in Arabidopsis. Plant Signal Behav, 2017. 12(11): p. e1376159 [PMID:28873003] Ruberti C,Lai Y,Brandizzi F Recovery from temporary endoplasmic reticulum stress in plants relies on the tissue-specific and largely independent roles of bZIP28 and bZIP60, as well as an antagonizing function of BAX-Inhibitor 1 upon the pro-adaptive signaling mediated by bZIP28. Plant J., 2018. 93(1): p. 155-165 [PMID:29124827] Kim JS,Yamaguchi-Shinozaki K,Shinozaki K ER-Anchored Transcription Factors bZIP17 and bZIP28 Regulate Root Elongation. Plant Physiol., 2018. 176(3): p. 2221-2230 [PMID:29367234]