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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
GSBRNA2T00000636001 |
| Common Name | GSBRNA2T00000636001 |
| Organism |
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| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
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| Family |
E2F/DP |
| Protein Properties |
Length: 107aa MW: 12523.8 Da PI: 10.1112 |
| Description |
E2F/DP family protein |
| Gene Model |
| Gene Model ID |
Type |
Source |
Coding Sequence |
| GSBRNA2T00000636001 | genome | Genoscope | View CDS |
|
| Signature Domain? help Back to Top |
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| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | E2F_TDP | 33.4 | 7.2e-11 | 9 | 54 | 22 | 71 |
E2F_TDP 22 e.givtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
+ + ++++ + v +r RiYD++N+L +++++++k k+ ++wkg
GSBRNA2T00000636001 9 DvDLFGIDDAVAKF---GV--ERWRIYDVVNILVSVGVLSRKGKSLYSWKG 54
34666777777777...88..99**************************98 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
| GO:0005634 | Cellular Component | nucleus |
| GO:0005667 | Cellular Component | transcription factor complex |
| GO:0003677 | Molecular Function | DNA binding |
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
| Expression --
Description ? help
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| Source |
Description |
| Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in mid-S phase. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:15308755}. |
| Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected at the G1/S transition, but increases during the progression into S phase and peaks after the passage into G2. {ECO:0000269|PubMed:11786543}. |
| Uniprot | TISSUE SPECIFICITY: High expression in young cotyledons and leaves, hypocotyls, shoot apical meristem, roots and mature pollen grains, moderate in developing trichomes, flowers and at early stages of developing anthers, and barely detectable in mature leaves. Not detected in primary root meristem, emerging lateral roots, pistils, developing embryos and siliques. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}. |
| Uniprot | TISSUE SPECIFICITY: Preferentially expressed in proliferating tissues. Highly expressed in young stalk and young flowers. Lower expression in young leaves and mature flowers. Detected in cotyledonary vascular tissues, the shoot apical meristem, the base of trichomes, the fully developed stomata, the central root cylinder and in the columella of lateral roots but not in the primary root tips or in the leaf epidermal cells. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:19937368}. |
| Functional Description ? help
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| Source |
Description |
| UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}. |
| UniProt | Inhibitor of E2F-dependent regulation of gene expression. Binds specifically the E2 recognition site as a monomer without interacting with DP proteins. May be up-regulating E2FA and down-regulating repressors of cell cycle progression. Promotes cell proliferation and represses cell elongation. Regulated by proteolysis via a ubiquitin-proteasome pathway. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:19937368}. |
| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: Down-regulated posttranscroptionally by auxin. {ECO:0000269|PubMed:19937368}. |
