PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

evm_27.model.AmTr_v1.0_scaffold00025.64

Common Name

AMTR_s00025p00081740

Organism

Amborella trichopoda

Taxonomic ID

13333

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; basal Magnoliophyta; Amborellales; Amborellaceae; Amborella

Family

bHLH

Protein Properties

Length: 179aa MW: 19565.4 Da PI: 6.5181

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm_27.model.AmTr_v1.0_scaffold00025.64	genome	TAGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	12.1	0.00036	2	18	4	20
HHHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsaf 20 +h +Er+RR+++N+ + evm_27.model.AmTr_v1.0_scaffold00025.64 2 SHITVERNRRKQMNEHL 18 7999**********987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	9.29E-9	1	58	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	6.22E-5	1	41	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010374	Biological Process	stomatal complex development
GO:0005634	Cellular Component	nucleus
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 179 aa Download sequence Send to blast
MSHITVERNR RKQMNEHLKG DQASIISGVI EFIKELHEVL QSLEAKKRRK SLSPSPGPSP 60 TPSPRLAASN NEIGFDNVSG LVGSCNSSVA DVEAKISGSN VVLRTVSRRI PGQVVKIIRV 120 LETLSFEILH LNISSMDDTV LYIFTIKIGL ECQLSVEELV QEVQQTFSGD SQNDIILA*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	45	49	KKRRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Together with FMA and SPCH, regulates the stomata formation. Required for the differentiation of stomatal guard cells, by promoting successive asymmetric cell divisions and the formation of guard mother cells. Promotes the conversion of the leaf epidermis into stomata. {ECO:0000269\|PubMed:17183265, ECO:0000269\|PubMed:17183267}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By UV, flagellin, and jasmonic acid (JA) treatments. {ECO:0000269\|PubMed:12679534}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020527048.1	1e-126	transcription factor MUTE isoform X2
Swissprot	Q9M8K6	5e-65	MUTE_ARATH; Transcription factor MUTE
TrEMBL	W1PY07	1e-125	W1PY07_AMBTC; Uncharacterized protein
STRING	ERN12350	1e-126	(Amborella trichopoda)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Representative plant	OGRP253	15	131

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G06120.1	3e-64	bHLH family protein

Link Out ? help Back to Top
Phytozome	evm_27.model.AmTr_v1.0_scaffold00025.64

Publications ? help Back to Top
Casson S,Gray JE Influence of environmental factors on stomatal development. New Phytol., 2008. 178(1): p. 9-23 [PMID:18266617] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Amborella Genome Project The Amborella genome and the evolution of flowering plants. Science, 2013. 342(6165): p. 1241089 [PMID:24357323] Balcerowicz M,Ranjan A,Rupprecht L,Fiene G,Hoecker U Auxin represses stomatal development in dark-grown seedlings via Aux/IAA proteins. Development, 2014. 141(16): p. 3165-76 [PMID:25063454] de Marcos A, et al. Transcriptional profiles of Arabidopsis stomataless mutants reveal developmental and physiological features of life in the absence of stomata. Front Plant Sci, 2015. 6: p. 456 [PMID:26157447] Mahoney AK, et al. Functional analysis of the Arabidopsis thaliana MUTE promoter reveals a regulatory region sufficient for stomatal-lineage expression. Planta, 2016. 243(4): p. 987-98 [PMID:26748914] Klermund C, et al. LLM-Domain B-GATA Transcription Factors Promote Stomatal Development Downstream of Light Signaling Pathways in Arabidopsis thaliana Hypocotyls. Plant Cell, 2016. 28(3): p. 646-60 [PMID:26917680] Fu ZW,Wang YL,Lu YT,Yuan TT Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis. Plant Sci., 2016. 252: p. 282-289 [PMID:27717464] Qi X, et al. Autocrine regulation of stomatal differentiation potential by EPF1 and ERECTA-LIKE1 ligand-receptor signaling. Elife, 2018. [PMID:28266915] Raissig MT, et al. Mobile MUTE specifies subsidiary cells to build physiologically improved grass stomata. Science, 2017. 355(6330): p. 1215-1218 [PMID:28302860] Lee JH,Jung JH,Park CM Light Inhibits COP1-Mediated Degradation of ICE Transcription Factors to Induce Stomatal Development in Arabidopsis. Plant Cell, 2017. 29(11): p. 2817-2830 [PMID:29070509] Han SK, et al. MUTE Directly Orchestrates Cell-State Switch and the Single Symmetric Division to Create Stomata. Dev. Cell, 2018. 45(3): p. 303-315.e5 [PMID:29738710]