PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G24260.1
Common NameBHLH66, EN95, F27D4.17, LRL1
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 350aa    MW: 36521.8 Da    PI: 6.8623
Description LJRHL1-like 1
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G24260.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH35.81.4e-11149194555
                  HHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   5 hnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                  h+++Er RR+ri +++  L+el+P+ +      K +Ka++L + ++Y+k Lq
  AT2G24260.1 149 HSIAERLRRERIAERMKALQELVPNgN------KTDKASMLDEIIDYVKFLQ 194
                  99***********************55......******************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474594.32E-17142203IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.57E-13142198No hitNo description
PROSITE profilePS5088817.409144193IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.7E-16146203IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000106.2E-9149194IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.0E-14150199IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045944Biological Processpositive regulation of transcription from RNA polymerase II promoter
GO:0048767Biological Processroot hair elongation
GO:0005634Cellular Componentnucleus
GO:0001046Molecular Functioncore promoter sequence-specific DNA binding
GO:0001228Molecular Functiontranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000230anatomyinflorescence meristem
PO:0000256anatomyroot hair cell
PO:0000262anatomytrichoblast
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0025281anatomypollen
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 350 aa     Download sequence    Send to blast
MMNSSLLTPS SSSSSHIQTP STTFDHEDFL DQIFSSAPWP SVVDDAHPLP SDGFHGHDVD  60
SRNQPIMMMP LNDGSSVHAL YNGFSVAGSL PNFQIPQGSG GGLMNQQGQT QTQTQPQASA  120
STATGGTVAA PPQSRTKIRA RRGQATDPHS IAERLRRERI AERMKALQEL VPNGNKTDKA  180
SMLDEIIDYV KFLQLQVKVL SMSRLGGAAS VSSQISEAGG SHGNASSAMV GGSQTAGNSN  240
DSVTMTEHQV AKLMEEDMGS AMQYLQGKGL CLMPISLATA ISTATCHSRN PLIPGAVADV  300
GGPSPPNLSG MTIQSTSTKM GSGNGKLNGN GVTERSSSIA VKEAVSVSKA
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1153158RLRRER
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.207920.0root
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1865027090.0
Genevisible265989_at0.0
Expression AtlasAT2G24260-
AtGenExpressAT2G24260-
ATTED-IIAT2G24260-
Functional Description ? help Back to Top
Source Description
TAIREncodes a basic helix-loop-helix (bHLH) protein that regulates root hair development. One of the three Arabidopsis homologs of the Lotus japonicus ROOTHAIRLESS1 (LjRHL1) gene: At2g24260 (AtLRL1), At4g30980 (AtLRL2), and At5g58010 (AtLRL3).
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00659PBMTransfer from Pp3c14_15890Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G24260.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By cold, UV, ethylene (ACC), flagellin, jasmonic acid (JA), and salicylic acid (SA) treatments. {ECO:0000269|PubMed:12679534}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G24260
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1763700.0AK176370.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor (bHLH066), complete cds, clone: RAFL24-07-J21.
GenBankBT0265120.0BT026512.1 Arabidopsis thaliana At2g24260 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_180003.10.0LJRHL1-like 1
SwissprotQ9ZUG90.0BH066_ARATH; Transcription factor bHLH66
TrEMBLA0A178VTY50.0A0A178VTY5_ARATH; LRL1
STRINGAT2G24260.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM30422763
Representative plantOGRP5816313
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  5. Contento AL,Kim SJ,Bassham DC
    Transcriptome profiling of the response of Arabidopsis suspension culture cells to Suc starvation.
    Plant Physiol., 2004. 135(4): p. 2330-47
    [PMID:15310832]
  6. Karas B, et al.
    Conservation of lotus and Arabidopsis basic helix-loop-helix proteins reveals new players in root hair development.
    Plant Physiol., 2009. 151(3): p. 1175-85
    [PMID:19675148]
  7. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  8. Bruex A, et al.
    A gene regulatory network for root epidermis cell differentiation in Arabidopsis.
    PLoS Genet., 2012. 8(1): p. e1002446
    [PMID:22253603]
  9. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  10. Lin Q, et al.
    GLABRA2 Directly Suppresses Basic Helix-Loop-Helix Transcription Factor Genes with Diverse Functions in Root Hair Development.
    Plant Cell, 2015. 27(10): p. 2894-906
    [PMID:26486447]
  11. Zhang J, et al.
    Sperm cells are passive cargo of the pollen tube in plant fertilization.
    Nat Plants, 2017. 3: p. 17079
    [PMID:28585562]