PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 870142
Common NameARALYDRAFT_321761, ARALYDRAFT_669586, WRKY54
Organism
Arabidopsis lyrata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family WRKY
Protein Properties Length: 338aa    MW: 37599.6 Da    PI: 5.961
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
870142genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY84.21.2e-26152212259
             --SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSSTTEEEEEEES--SS- CS
    WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedpkvveitYegeHnhe 59 
             +D y+WrKYGqKe+ +++fprsY+rCt++   gC+++k+v+++++dp++++itY g H+++
  870142 152 EDRYAWRKYGQKEILNTTFPRSYFRCTHKptqGCKATKQVQKKEQDPEMFQITYIGYHTCT 212
             7***************************9999***************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.808.8E-26139212IPR003657WRKY domain
SuperFamilySSF1182905.23E-24145212IPR003657WRKY domain
PROSITE profilePS5081120.576146214IPR003657WRKY domain
SMARTSM007742.5E-36151213IPR003657WRKY domain
PfamPF031068.6E-25152211IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009751Biological Processresponse to salicylic acid
GO:0031347Biological Processregulation of defense response
GO:1900056Biological Processnegative regulation of leaf senescence
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 338 aa     Download sequence    Send to blast
MDSNSNNTKS IKRKVVDQLV EGYEFATQLQ LLLSHQHSKQ YHIDQTRLVS GSGSVSGVPD  60
PVDELMSKIL GSFHKTISVL DSFDPVTVSV PISVEGSWNA SCGDDSATPA SCNGGDSGDS  120
KKKRLGVGKG KRGCYTRKKR SHTRIVEARS SEDRYAWRKY GQKEILNTTF PRSYFRCTHK  180
PTQGCKATKQ VQKKEQDPEM FQITYIGYHT CTATDQTHTK TEPFDQEIIM DLEKTLAAST  240
VQNHVNAMVQ EQENNISSVI AVGAGMVKEE ENNNGDQSKD YCEGSSTGED LSLVWQETMM  300
FDDHQNNYYC GEISTTSHQF GFIDNDQLSS LFDSYCA*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6ir8_A8e-19146211368OsWRKY45
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1121139KKRLGVGKGKRGCYTRKKR
2137141KKRSH
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Together with WRKY70, negative regulator of developmental senescence, probably via the regulation of several senescence-associated markers genes (PubMed:22268143). Positive regulator of EDS1-dependent defense against E.amylovora (PubMed:22316300). In collaboration with WRKY70, prevents stomatal closure and, consequently, osmotic stress tolerance (PubMed:23815736). Together with WRKY46 and WRKY70, promotes brassinosteroid (BR)-regulated plant growth but prevent drought response by modulating gene expression (PubMed:28576847). Negative regulator of SA biosynthesis (PubMed:28837631). Prevents defense response to the necrotrophic pathogens P.carotovorum and B.cinerea, but promotes defense against biotrophic/hemibiotrophic pathogens P.syringae pv. tomato (Pst) DC3000, probably by regulating negatively the jasmonic acid (JA)/ethylene (ET) and positively the salicylic acid (SA) signaling pathways (PubMed:28837631). {ECO:0000250|UniProtKB:Q9SUP6, ECO:0000269|PubMed:22268143, ECO:0000269|PubMed:22316300, ECO:0000269|PubMed:23815736, ECO:0000269|PubMed:28576847, ECO:0000269|PubMed:28837631, ECO:0000303|PubMed:28837631}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap870142
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by reactive oxygen species (ROS) and salicylic acid (SA) (PubMed:22268143). Early but transient accumulation after osmotic stress (e.g. polyethylene glycol, PEG) (PubMed:23815736). Up-regulated by E.amylovora (PubMed:22316300). {ECO:0000269|PubMed:22268143, ECO:0000269|PubMed:22316300, ECO:0000269|PubMed:23815736}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF4262530.0AF426253.1 Arabidopsis thaliana WRKY transcription factor 54 (WRKY54) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002881532.10.0probable WRKY transcription factor 54
RefseqXP_002881736.10.0probable WRKY transcription factor 54
SwissprotQ93WU80.0WRK54_ARATH; Probable WRKY transcription factor 54
TrEMBLD7LFT90.0D7LFT9_ARALL; Predicted protein
STRINGAl_scaffold_0004_23050.0(Arabidopsis lyrata)
STRINGfgenesh1_pm.C_scaffold_40018180.0(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM113621631
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G40750.10.0WRKY DNA-binding protein 54
Publications ? help Back to Top
  1. Wang Y,Joshi T,Zhang XS,Xu D,Chen L
    Inferring gene regulatory networks from multiple microarray datasets.
    Bioinformatics, 2006. 22(19): p. 2413-20
    [PMID:16864593]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Lee MH,Jeon HS,Kim HG,Park OK
    An Arabidopsis NAC transcription factor NAC4 promotes pathogen-induced cell death under negative regulation by microRNA164.
    New Phytol., 2017. 214(1): p. 343-360
    [PMID:28032643]
  4. Timmermann T, et al.
    Paraburkholderia phytofirmans PsJN Protects Arabidopsis thaliana Against a Virulent Strain of Pseudomonas syringae Through the Activation of Induced Resistance.
    Mol. Plant Microbe Interact., 2017. 30(3): p. 215-230
    [PMID:28118091]
  5. Chen J, et al.
    Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses.
    Plant Cell, 2017. 29(6): p. 1425-1439
    [PMID:28576847]
  6. Li J,Zhong R,Palva ET
    WRKY70 and its homolog WRKY54 negatively modulate the cell wall-associated defenses to necrotrophic pathogens in Arabidopsis.
    PLoS ONE, 2017. 12(8): p. e0183731
    [PMID:28837631]