PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

478415

Common Name

ARALYDRAFT_478415

Organism

Arabidopsis lyrata

Taxonomic ID

81972

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bZIP

Protein Properties

Length: 675aa MW: 73370.4 Da PI: 6.0272

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
478415	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	29.9	1.2e-09	191	236	5	50
CHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 5 krerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkele 50 ++ +r ++NRe+A+ sR+RKk+++eeLe+kvk++ a +L ++ 478415 191 RKLIRQIRNRESAQLSRLRKKQQTEELERKVKSMNATIAELNGKIA 236 6789*****************************9998877776665 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.20.5.170	1.6E-12	186	249	No hit	No description
SMART	SM00338	9.3E-12	186	251	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	9.634	189	252	IPR004827	Basic-leucine zipper domain
Pfam	PF00170	2.5E-8	191	248	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	7.5E-10	191	249	No hit	No description
CDD	cd14704	2.99E-15	192	242	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006990	Biological Process	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0009408	Biological Process	response to heat
GO:0005635	Cellular Component	nuclear envelope
GO:0005654	Cellular Component	nucleoplasm
GO:0005783	Cellular Component	endoplasmic reticulum
GO:0016021	Cellular Component	integral component of membrane
GO:0048471	Cellular Component	perinuclear region of cytoplasm
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 675 aa Download sequence Send to blast
MTESTFVIAP PPEIPNLNPS MFSESDMISI PPLDPLFLSD SDPISMDAPI SDLDFLLDDE 60 NGDFADFDFS FENSDDFFDF DLAEPAVVIP EEIGNSRSNL DSSENRSGDG GLEGRSDSVH 120 SQVSSQGSKT FVSDTVDALS SPESSNHQKS SVSKRKNENG DSSGELRSCK YQKSDDKSVA 180 TNNEGDDDDK RKLIRQIRNR ESAQLSRLRK KQQTEELERK VKSMNATIAE LNGKIAYVMA 240 ENVALRQQMA VASGAPPMNP YMAAPPLPYQ WMPYPPYPVR GYGSQTPLVP IPKLNPKPVS 300 SCRPKKADSK KNEGKSKLKK VASISFIGIL FFMFLFGTLV PFMNVNYGGE GGSFGGLSKY 360 DGHRYYDEHK GKVLMVGDGS DVRRESGISE GNIHSSRIIH GERDSCGGVD YNGHPKVEGR 420 SSSLSNASDP LFASLYVPRN DGLVKIDGNL IIHSVLASEK ATALGKKNIT ETVKSKEPDL 480 TMPGALSSAI AVPEVRGNAA MLPHSTALSS EGKRLHQWFH EGGSGTLMDY SMCTEVFQFD 540 IAPGAIVPSS VSNISAEHLQ NVTTHGKRMK NRRILEGLPV SLVASELNIT GTQPNKDAQN 600 KTFHGNTNKP TSSSSMVVSV LLDPREVVDS ENDRVVPPNP KSLSRIFVVV LLDSVKYVTY 660 SCVLPRSGLH LVAT*

Sequence ? help Back to Top

Protein Sequence Length: 675 aa Download sequence Send to blast

MTESTFVIAP PPEIPNLNPS MFSESDMISI PPLDPLFLSD SDPISMDAPI SDLDFLLDDE  60
NGDFADFDFS FENSDDFFDF DLAEPAVVIP EEIGNSRSNL DSSENRSGDG GLEGRSDSVH  120
SQVSSQGSKT FVSDTVDALS SPESSNHQKS SVSKRKNENG DSSGELRSCK YQKSDDKSVA  180
TNNEGDDDDK RKLIRQIRNR ESAQLSRLRK KQQTEELERK VKSMNATIAE LNGKIAYVMA  240
ENVALRQQMA VASGAPPMNP YMAAPPLPYQ WMPYPPYPVR GYGSQTPLVP IPKLNPKPVS  300
SCRPKKADSK KNEGKSKLKK VASISFIGIL FFMFLFGTLV PFMNVNYGGE GGSFGGLSKY  360
DGHRYYDEHK GKVLMVGDGS DVRRESGISE GNIHSSRIIH GERDSCGGVD YNGHPKVEGR  420
SSSLSNASDP LFASLYVPRN DGLVKIDGNL IIHSVLASEK ATALGKKNIT ETVKSKEPDL  480
TMPGALSSAI AVPEVRGNAA MLPHSTALSS EGKRLHQWFH EGGSGTLMDY SMCTEVFQFD  540
IAPGAIVPSS VSNISAEHLQ NVTTHGKRMK NRRILEGLPV SLVASELNIT GTQPNKDAQN  600
KTFHGNTNKP TSSSSMVVSV LLDPREVVDS ENDRVVPPNP KSLSRIFVVV LLDSVKYVTY  660
SCVLPRSGLH LVAT*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in ER stress responses. Functions as a stress sensor and transducer in ER stress signaling pathway. After proteolysis by SBT6.1 (S1P) and S2P, the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones (PubMed:18156219, PubMed:18634751, PubMed:18849477, PubMed:20876872). Following ER stress, activates proteins involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth (PubMed:20876872). {ECO:0000269\|PubMed:18156219, ECO:0000269\|PubMed:18634751, ECO:0000269\|PubMed:18849477, ECO:0000269\|PubMed:20876872}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00345	DAP	Transfer from AT3G10800	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	478415

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock. {ECO:0000269\|PubMed:18849477}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK226928	0.0	AK226928.1 Arabidopsis thaliana mRNA for bZIP transcription factor AtbZip28, complete cds, clone: RAFL09-25-P21.
GenBank	BT002502	0.0	BT002502.1 Arabidopsis thaliana putative bZIP transcription factor (At3g10800) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002882698.1	0.0	bZIP transcription factor 28 isoform X1
Swissprot	Q9SG86	0.0	BZP28_ARATH; bZIP transcription factor 28
TrEMBL	D7L9R1	0.0	D7L9R1_ARALL; BZIP transcription factor family protein
STRING	fgenesh2_kg.3__1116__AT3G10800.1	0.0	(Arabidopsis lyrata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM14397	18	22

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10800.1	0.0	bZIP family protein

Link Out ? help Back to Top
Phytozome	478415
Entrez Gene	9318764

Publications ? help Back to Top
Deng Y,Srivastava R,Howell SH Protein kinase and ribonuclease domains of IRE1 confer stress tolerance, vegetative growth, and reproductive development in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(48): p. 19633-8 [PMID:24145452] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Nagashima Y,Iwata Y,Ashida M,Mishiba K,Koizumi N Exogenous salicylic acid activates two signaling arms of the unfolded protein response in Arabidopsis. Plant Cell Physiol., 2014. 55(10): p. 1772-8 [PMID:25138441] Sun L,Zhang SS,Lu SJ,Liu JX Site-1 protease cleavage site is important for the ER stress-induced activation of membrane-associated transcription factor bZIP28 in Arabidopsis. Sci China Life Sci, 2015. 58(3): p. 270-5 [PMID:25634523] Zhang L,Chen H,Brandizzi F,Verchot J,Wang A The UPR branch IRE1-bZIP60 in plants plays an essential role in viral infection and is complementary to the only UPR pathway in yeast. PLoS Genet., 2015. 11(4): p. e1005164 [PMID:25875739] Ma ZX, et al. The THERMOSENSITIVE MALE STERILE 1 Interacts with the BiPs via DnaJ Domain and Stimulates Their ATPase Enzyme Activities in Arabidopsis. PLoS ONE, 2015. 10(7): p. e0132500 [PMID:26186593] Sagor GH, et al. The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis. Front Plant Sci, 2015. 6: p. 687 [PMID:26442007] Kørner CJ,Du X,Vollmer ME,Pajerowska-Mukhtar KM Endoplasmic Reticulum Stress Signaling in Plant Immunity--At the Crossroad of Life and Death. Int J Mol Sci, 2015. 16(11): p. 26582-98 [PMID:26556351] Zeng Y, et al. Unique COPII component AtSar1a/AtSec23a pair is required for the distinct function of protein ER export in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A., 2015. 112(46): p. 14360-5 [PMID:26578783] Meng Z,Ruberti C,Gong Z,Brandizzi F CPR5 modulates salicylic acid and the unfolded protein response to manage tradeoffs between plant growth and stress responses. Plant J., 2017. 89(3): p. 486-501 [PMID:27747970] Nawkar GM, et al. HY5, a positive regulator of light signaling, negatively controls the unfolded protein response in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(8): p. 2084-2089 [PMID:28167764] Iwata Y, et al. Activation of the Arabidopsis membrane-bound transcription factor bZIP28 is mediated by site-2 protease, but not site-1 protease. Plant J., 2017. 91(3): p. 408-415 [PMID:28407373] Zhang SS, et al. Tissue-Specific Transcriptomics Reveals an Important Role of the Unfolded Protein Response in Maintaining Fertility upon Heat Stress in Arabidopsis. Plant Cell, 2017. 29(5): p. 1007-1023 [PMID:28442596] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Kataoka R,Takahashi M,Suzuki N Coordination between bZIP28 and HSFA2 in the regulation of heat response signals in Arabidopsis. Plant Signal Behav, 2017. 12(11): p. e1376159 [PMID:28873003] Ruberti C,Lai Y,Brandizzi F Recovery from temporary endoplasmic reticulum stress in plants relies on the tissue-specific and largely independent roles of bZIP28 and bZIP60, as well as an antagonizing function of BAX-Inhibitor 1 upon the pro-adaptive signaling mediated by bZIP28. Plant J., 2018. 93(1): p. 155-165 [PMID:29124827] Kim JS,Yamaguchi-Shinozaki K,Shinozaki K ER-Anchored Transcription Factors bZIP17 and bZIP28 Regulate Root Elongation. Plant Physiol., 2018. 176(3): p. 2221-2230 [PMID:29367234]