PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_9897_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family C3H
Protein Properties Length: 493aa    MW: 55265.7 Da    PI: 8.3334
Description C3H family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_9897_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-CCCH18.24.5e-064044201127
                    GTS--TTTTT-SS-SSS CS
        zf-CCCH  11 rtGtCkyGdrCkFaHgp 27 
                    r+G+C++Gd+Ck+ H++
  Neem_9897_f_1 404 RMGFCPFGDSCKYFHPK 420
                    89*************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.200.201.5E-2368148No hitNo description
CDDcd14137069361No hitNo description
SuperFamilySSF561121.48E-8973387IPR011009Protein kinase-like domain
PfamPF000693.7E-6574358IPR000719Protein kinase domain
SMARTSM002206.2E-9074358IPR000719Protein kinase domain
PROSITE profilePS5001144.21674358IPR000719Protein kinase domain
PROSITE patternPS00107080104IPR017441Protein kinase, ATP binding site
Gene3DG3DSA:1.10.510.101.6E-61149359No hitNo description
PROSITE patternPS001080195207IPR008271Serine/threonine-protein kinase, active site
PROSITE profilePS501039.807403421IPR000571Zinc finger, CCCH-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006468Biological Processprotein phosphorylation
GO:0004672Molecular Functionprotein kinase activity
GO:0005524Molecular FunctionATP binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 493 aa     Download sequence    Send to blast
MASVGVAPTS CMRESSGHTV AGVDKLPEEM NDMKIRDDKE MEATVVDGNG TETGHIIVTT  60
IGGRNGQPKQ TISYMAERIV GQGSFGVVFQ AKCLETGETV AIKKVLQDKR YKNRELQTMR  120
LLDHPNVVSL KHCFFSTTEK DELYLNLVLE YVPETVHRVI KHFNKLNQRM PMIYVKLYAY  180
QIFRALSYIH RSIGVCHRDI KPQNLLVNPH THQVKLCDFG SAKVLVKGEP NISYICSRYY  240
RAPELIFGAT EYTTAIDIWS AGCVVAELLL GKPLFPGDSG VDQLVEIIKV LGTPTREEIK  300
CMNPNYTEFK FPQIKAHPWH KIFPKRMPPE AVDLVSRLLQ YSPNLRCSAL DALIHPFFDE  360
LRDPNTRLPN GRFLPPLFNF KSHENAIFKA SNTSEQKLYG TIFRMGFCPF GDSCKYFHPK  420
NTQNAGAPGF VATGFIDTAQ SSSVDPRIYL VGGTSLPGDM VRDSMGMSWG NLPPSLKPPP  480
EGGYPPLPFV DWG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5t31_A1e-1702738420366Glycogen synthase kinase-3 beta
5t31_B1e-1702738420366Glycogen synthase kinase-3 beta
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtMay mediate extracellular signals to regulate transcription in differentiating cells.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006480288.10.0shaggy-related protein kinase alpha
RefseqXP_024037720.10.0shaggy-related protein kinase alpha
SwissprotP432880.0KSG1_ARATH; Shaggy-related protein kinase alpha
TrEMBLA0A498IJG80.0A0A498IJG8_MALDO; Uncharacterized protein
STRINGXP_006428242.10.0(Citrus clementina)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G12020.23e-18WRKY family protein
Publications ? help Back to Top
  1. Dornelas MC,Wittich P,von Recklinghausen I,van Lammeren A,Kreis M
    Characterization of three novel members of the Arabidopsis SHAGGY-related protein kinase (ASK) multigene family.
    Plant Mol. Biol., 1999. 39(1): p. 137-47
    [PMID:10080716]
  2. Dornelas MC,Van Lammeren AA,Kreis M
    Arabidopsis thaliana SHAGGY-related protein kinases (AtSK11 and 12) function in perianth and gynoecium development.
    Plant J., 2000. 21(5): p. 419-29
    [PMID:10758494]
  3. Gachon C,Saindrenan P
    Real-time PCR monitoring of fungal development in Arabidopsis thaliana infected by Alternaria brassicicola and Botrytis cinerea.
    Plant Physiol. Biochem., 2004. 42(5): p. 367-71
    [PMID:15191738]
  4. Han L,Mason M,Risseeuw EP,Crosby WL,Somers DE
    Formation of an SCF(ZTL) complex is required for proper regulation of circadian timing.
    Plant J., 2004. 40(2): p. 291-301
    [PMID:15447654]
  5. Langlois-Meurinne M,Gachon CM,Saindrenan P
    Pathogen-responsive expression of glycosyltransferase genes UGT73B3 and UGT73B5 is necessary for resistance to Pseudomonas syringae pv tomato in Arabidopsis.
    Plant Physiol., 2005. 139(4): p. 1890-901
    [PMID:16306146]
  6. Dal Santo S, et al.
    Stress-induced GSK3 regulates the redox stress response by phosphorylating glucose-6-phosphate dehydrogenase in Arabidopsis.
    Plant Cell, 2012. 24(8): p. 3380-92
    [PMID:22885737]
  7. Zhu JY, et al.
    The F-box Protein KIB1 Mediates Brassinosteroid-Induced Inactivation and Degradation of GSK3-like Kinases in Arabidopsis.
    Mol. Cell, 2017. 66(5): p. 648-657.e4
    [PMID:28575660]
  8. Mittal S, et al.
    Comparative Analysis of CDPK Family in Maize, Arabidopsis, Rice, and Sorghum Revealed Potential Targets for Drought Tolerance Improvement.
    Front Chem, 2017. 5: p. 115
    [PMID:29312925]
  9. Huang KC,Lin WC,Cheng WH
    Salt hypersensitive mutant 9, a nucleolar APUM23 protein, is essential for salt sensitivity in association with the ABA signaling pathway in Arabidopsis.
    BMC Plant Biol., 2018. 18(1): p. 40
    [PMID:29490615]
  10. Bianchi MW,Guivarc'h D,Thomas M,Woodgett JR,Kreis M
    Arabidopsis homologs of the shaggy and GSK-3 protein kinases: molecular cloning and functional expression in Escherichia coli.
    Mol. Gen. Genet., 1994. 242(3): p. 337-45
    [PMID:7509023]
  11. Dornelas MC,Lejeune B,Dron M,Kreis M
    The Arabidopsis SHAGGY-related protein kinase (ASK) gene family: structure, organization and evolution.
    Gene, 1998. 212(2): p. 249-57
    [PMID:9611268]