PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_9151_f_2
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family ERF
Protein Properties Length: 203aa    MW: 22136.5 Da    PI: 8.8294
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_9151_f_2genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP265.88.5e-212473255
            AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                   +y+GVr ++ +gr++AeIrdp   gk++r++lg+f+taeeAa+a++aa+++++g
  Neem_9151_f_2 24 RYRGVRKRP-WGRYAAEIRDP---GKKTRVWLGTFDTAEEAARAYDAAAREFRG 73
                   69*******.**********8...557************************997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5103224.52481IPR001471AP2/ERF domain
CDDcd000181.03E-182481No hitNo description
SuperFamilySSF541717.19E-232482IPR016177DNA-binding domain
PfamPF008472.0E-142473IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.9E-322482IPR001471AP2/ERF domain
SMARTSM003808.5E-392487IPR001471AP2/ERF domain
PRINTSPR003678.9E-122536IPR001471AP2/ERF domain
PRINTSPR003678.9E-124763IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 203 aa     Download sequence    Send to blast
MAPREKLTTG NTSSNPNPKD REVRYRGVRK RPWGRYAAEI RDPGKKTRVW LGTFDTAEEA  60
ARAYDAAARE FRGVKAKTNF PTPNEMGNNN FTRSPSQSST VESSSPPPPP PPPPLSLTLN  120
NYQGGGSCFP VAVGRPVVFF DVFSSGGPRD ACRFDRSVAD FCPGGTTQSD SDSSSVVVDY  180
DHTSSERRMI NLDLNLPPPP EVA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A2e-2224881479Ethylene-responsive transcription factor ERF096
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtActs as a transcriptional repressor. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways, and could also regulate other AtERFs. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:11487705, ECO:0000269|PubMed:9756931}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by jasmonate (JA) and by Alternaria brassicicola (locally and systemically), but only slightly by ethylene. Strong induction by wounding, cold or drought stress does not require EIN2, whereas induction by NaCl does. Transcripts accumulate in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by exogenous abscisic acid (ABA), and heat stress. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:12805630}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY7793396e-31AY779339.1 Gossypium hirsutum AP2/EREBP transcription factor ERF-1 mRNA, complete cds.
GenBankKP7801996e-31KP780199.1 Gossypium hirsutum C-repeat binding factor 16 (CBF16) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013464648.11e-64ethylene-responsive transcription factor 4
SwissprotO803402e-47ERF78_ARATH; Ethylene-responsive transcription factor 4
TrEMBLA0A072VB553e-63A0A072VB55_MEDTR; AP2 domain class transcription factor
STRINGevm.model.supercontig_131.832e-53(Carica papaya)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM10281650
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G15210.13e-25ethylene responsive element binding factor 4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Cao WH, et al.
    Modulation of ethylene responses affects plant salt-stress responses.
    Plant Physiol., 2007. 143(2): p. 707-19
    [PMID:17189334]
  3. Lyons R, et al.
    The RNA-binding protein FPA regulates flg22-triggered defense responses and transcription factor activity by alternative polyadenylation.
    Sci Rep, 2013. 3: p. 2866
    [PMID:24104185]
  4. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  5. Gao S, et al.
    A cotton miRNA is involved in regulation of plant response to salt stress.
    Sci Rep, 2016. 6: p. 19736
    [PMID:26813144]
  6. Zhou X, et al.
    The ERF11 Transcription Factor Promotes Internode Elongation by Activating Gibberellin Biosynthesis and Signaling.
    Plant Physiol., 2016. 171(4): p. 2760-70
    [PMID:27255484]
  7. Liu W, et al.
    The ethylene response factor AtERF4 negatively regulates the iron deficiency response in Arabidopsis thaliana.
    PLoS ONE, 2017. 12(10): p. e0186580
    [PMID:29045490]