PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_39666_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family NAC
Protein Properties Length: 441aa    MW: 49775.1 Da    PI: 9.1153
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_39666_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM119.14.3e-37681791128
             NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevls 94 
                     + pGfrF+Ptd el+++yLkkk+eg+++ + evi+e++i+++ePwdLp k+v ++++ew+fF+ r +ky++g++++rat+ gyWkatgk+++v s
  Neem_39666_f_1  68 MFPGFRFSPTDVELISYYLKKKIEGSENCV-EVISEIEICRYEPWDLPaKSVIQSDNEWFFFCARGRKYPNGSQSRRATELGYWKATGKERNVRS 161
                     579************************877.99***************667777899************************************99 PP

             NAM  95 kkgelvglkktLvfykgrapkgektdWvmheyrl 128
                                     grapkge+t+W+mhey +
  Neem_39666_f_1 162 ----------------GRAPKGERTEWIMHEYCM 179
                     ................89**************87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019419.42E-4558194IPR003441NAC domain
PROSITE profilePS5100532.59668223IPR003441NAC domain
PfamPF023659.2E-1870178IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009845Biological Processseed germination
GO:0009938Biological Processnegative regulation of gibberellic acid mediated signaling pathway
GO:0033619Biological Processmembrane protein proteolysis
GO:0048573Biological Processphotoperiodism, flowering
GO:0071472Biological Processcellular response to salt stress
GO:0005634Cellular Componentnucleus
GO:0005886Cellular Componentplasma membrane
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 441 aa     Download sequence    Send to blast
MGARRSKKRL QILSLLSLAK VTKKRRKSNR KDRNRIGATI EEERKSCKLE NMAGVSRETQ  60
MSIAASSMFP GFRFSPTDVE LISYYLKKKI EGSENCVEVI SEIEICRYEP WDLPAKSVIQ  120
SDNEWFFFCA RGRKYPNGSQ SRRATELGYW KATGKERNVR SGRAPKGERT EWIMHEYCME  180
GASQDSLVVC RLRKNSEFRL NNISNQSSHG RRMNSSNCAV SGGTDKTGMS EGDKAVESSS  240
KKCTSSNDSY SIEQNDWTSE AEQKLWDDAN PTESSSHQQD FLGEDDLYAD ILKDDIIKLD  300
ETSLSTTPVL PPVVGNQQET ERIPQQETEG IPQQHAEAFS LQADPFQGTA NRRIKLRKQR  360
PGLSRSRQAT GLSCGCGVLA VVVISQSSVH FMSFISGGCI CGNCFLTLVC CKKARRQSGS  420
NNRRIERHWR MHCKTLLQTW S
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3ulx_A2e-32541922165Stress-induced transcription factor NAC1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1626KKRLQILSLLSLAKVTKKRRK
22226KKRRK
3350357NRRIKLRK
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP), probably via metalloprotease activity. Regulates gibberellic acid-mediated salt-responsive repression of seed germination and flowering via FT, thus delaying seed germination under high salinity conditions. {ECO:0000269|PubMed:17410378, ECO:0000269|PubMed:18363782, ECO:0000269|PubMed:19704528, ECO:0000269|PubMed:19704545}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00280DAPTransfer from AT2G27300Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By high salt stress (PubMed:19704545, PubMed:17410378, PubMed:18363782, PubMed:19704528). Repressed by gibberellic acid (GA), but induced by the GA biosynthetic inhibitor paclabutrazol (PAC) (PubMed:18363782). Accumulates transiently in seeds upon imbibition (PubMed:19704545, PubMed:17410378, PubMed:18363782, PubMed:19704528). Induced by drought stress (PubMed:17158162). {ECO:0000269|PubMed:17158162, ECO:0000269|PubMed:17410378, ECO:0000269|PubMed:18363782, ECO:0000269|PubMed:19704528, ECO:0000269|PubMed:19704545}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006424149.11e-167NAC domain-containing protein 89
RefseqXP_006481513.11e-167NAC domain-containing protein 89
SwissprotQ9XIN74e-85NAC40_ARATH; NAC domain-containing protein 40
TrEMBLA0A2H5Q9F21e-167A0A2H5Q9F2_CITUN; Uncharacterized protein (Fragment)
STRINGXP_006481513.11e-167(Citrus sinensis)
STRINGXP_006424149.11e-167(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM104532533
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G27300.16e-79NTM1-like 8
Publications ? help Back to Top
  1. Liang M, et al.
    Subcellular Distribution of NTL Transcription Factors in Arabidopsis thaliana.
    Traffic, 2015. 16(10): p. 1062-74
    [PMID:26201836]
  2. Tian H, et al.
    NTL8 Regulates Trichome Formation in Arabidopsis by Directly Activating R3 MYB Genes TRY and TCL1.
    Plant Physiol., 2017. 174(4): p. 2363-2375
    [PMID:28649093]