PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_37177_f_1

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

DBB

Protein Properties

Length: 264aa MW: 29526.7 Da PI: 5.628

Description

DBB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_37177_f_1	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-B_box	21.1	6.5e-07	4	44	5	39
zf-B_box 5 kCpeHeekelqlfCedCqqllCedClleeHkg......Htv 39 C+ +e+ +++ C ++ lC++C e H H++ Neem_37177_f_1 4 QCDVCERAPATVICCADEAALCAKCDIEVHAAnklaskHQR 44 7*****************************65667777765 PP
2	zf-B_box	27	9e-09	53	86	2	35
zf-B_box 2 eerkCpeHeekelqlfCedCqqllCedClleeHk 35 + + C+ ++ek + +fC +++ l+C+dC + +H+ Neem_37177_f_1 53 KLPPCDICQEKTAFIFCVEDRALFCKDCDEPIHS 86 6789****************************94 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50119	9.3	1	47	IPR000315	B-box-type zinc finger
CDD	cd00021	1.15E-6	3	47	No hit	No description
SMART	SM00336	1.5E-9	4	47	IPR000315	B-box-type zinc finger
Pfam	PF00643	3.2E-5	4	44	IPR000315	B-box-type zinc finger
SMART	SM00336	1.7E-14	52	99	IPR000315	B-box-type zinc finger
PROSITE profile	PS50119	8.973	52	99	IPR000315	B-box-type zinc finger
Pfam	PF00643	2.5E-7	53	95	IPR000315	B-box-type zinc finger
CDD	cd00021	2.46E-7	55	98	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005622	Cellular Component	intracellular
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 264 aa Download sequence Send to blast
MKIQCDVCER APATVICCAD EAALCAKCDI EVHAANKLAS KHQRLLLQCL SNKLPPCDIC 60 QEKTAFIFCV EDRALFCKDC DEPIHSPGSL SANHQRFLAT GIRVALSSSC SKDAQRSRFE 120 PPPNQRVQQT PVKTPAQQSL SISSPWAMDD LLQFSDFESS DKKEQLEFGE LEWLADMGIF 180 SDQLPQEALA AAEVPQLPVS QSSNITSHRM PKFNMPQKKP RIEIVSQSSN ITSHRMPKFN 240 MPQKKPRIEM PDDDDEHFTV PDLG

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of seedling photomorphogenesis and light-regulated inhibition of hypocotyl elongation (PubMed:17605755, PubMed:18540109, PubMed:21685177). BBX24/STO and BBX25/STH function as transcriptional corepressors of HY5 activity, leading to the down-regulation of BBX22 expression. BBX24/STO acts additively with BBX25/STH during de-etiolation and the hypocotyl shade avoidance response (PubMed:23624715). Functions as negative regulator of photomorphogenic UV-B responses by interacting with both COP1 and HY5 (PubMed:22410790). May act as a transcription factor in the salt-stress response (PubMed:12909688). {ECO:0000269\|PubMed:12909688, ECO:0000269\|PubMed:17605755, ECO:0000269\|PubMed:18540109, ECO:0000269\|PubMed:21685177, ECO:0000269\|PubMed:22410790, ECO:0000269\|PubMed:23624715}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian regulation with a peak before dawn. {ECO:0000269\|PubMed:17605755}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024044545.1	1e-145	B-box zinc finger protein 25
Refseq	XP_024954583.1	1e-145	B-box zinc finger protein 25-like
Swissprot	Q96288	2e-96	BBX24_ARATH; B-box zinc finger protein 24
TrEMBL	A0A067DTY9	1e-144	A0A067DTY9_CITSI; Uncharacterized protein
STRING	XP_006478724.1	1e-144	(Citrus sinensis)
STRING	XP_006442999.1	1e-144	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2711	27	67

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G06040.1	7e-99	DBB family protein

Publications ? help Back to Top
Gangappa SN,Holm M,Botto JF Molecular interactions of BBX24 and BBX25 with HYH, HY5 HOMOLOG, to modulate Arabidopsis seedling development. Plant Signal Behav, 2014. [PMID:23733077] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Imtiaz M, et al. Identification and functional characterization of the BBX24 promoter and gene from chrysanthemum in Arabidopsis. Plant Mol. Biol., 2015. 89(1-2): p. 1-19 [PMID:26253592] Job N,Yadukrishnan P,Bursch K,Datta S,Johansson H Two B-Box Proteins Regulate Photomorphogenesis by Oppositely Modulating HY5 through their Diverse C-Terminal Domains. Plant Physiol., 2018. 176(4): p. 2963-2976 [PMID:29439209]