PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Neem_28340_f_1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
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Family | MYB | ||||||||
Protein Properties | Length: 403aa MW: 46176.4 Da PI: 8.0878 | ||||||||
Description | MYB family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | Myb_DNA-binding | 43.1 | 9.9e-14 | 114 | 159 | 1 | 46 |
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +g+W +eEde l++ vk++G+++W++I ++ + Rt+k+c++rw + Neem_28340_f_1 114 KGPWKAEEDEVLINHVKKYGPRDWSSIRSKGLLQRTGKSCRLRWVN 159 79*************************8887799**********87 PP | |||||||
2 | Myb_DNA-binding | 41.9 | 2.4e-13 | 170 | 209 | 3 | 44 |
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHH CS Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrw 44 +++ eE+ + +++ +++G++ W++Ia +++ gRt++++k++w Neem_28340_f_1 170 KFSLEEERIVIELQAEFGNK-WARIATYLP-GRTDNDVKNFW 209 799*****************.*********.*********** PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.60 | 2.8E-21 | 109 | 162 | IPR009057 | Homeodomain-like |
PROSITE profile | PS51294 | 21.904 | 109 | 165 | IPR017930 | Myb domain |
SuperFamily | SSF46689 | 4.3E-28 | 112 | 209 | IPR009057 | Homeodomain-like |
SMART | SM00717 | 4.6E-11 | 113 | 163 | IPR001005 | SANT/Myb domain |
CDD | cd00167 | 8.94E-11 | 116 | 161 | No hit | No description |
Pfam | PF13921 | 6.6E-12 | 117 | 167 | No hit | No description |
Gene3D | G3DSA:1.10.10.60 | 7.9E-18 | 163 | 215 | IPR009057 | Homeodomain-like |
PROSITE profile | PS51294 | 18.362 | 166 | 217 | IPR017930 | Myb domain |
SMART | SM00717 | 1.2E-12 | 167 | 215 | IPR001005 | SANT/Myb domain |
CDD | cd00167 | 6.78E-10 | 170 | 209 | No hit | No description |
Pfam | PF00249 | 3.5E-12 | 170 | 209 | IPR001005 | SANT/Myb domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0048235 | Biological Process | pollen sperm cell differentiation | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0003677 | Molecular Function | DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 403 aa Download sequence Send to blast |
MYKNFSVPSA IGGIAGSRCS HPILICRPTN GPPRAFYKSE SNHYLIPEHV LCFFAHSKVR 60 GYRVIKVISY PFECEKILGM WEYLWRVVGV TVLTVTFNSE KKKAMDGKRE EIRKGPWKAE 120 EDEVLINHVK KYGPRDWSSI RSKGLLQRTG KSCRLRWVNK LRPNLKNGCK FSLEEERIVI 180 ELQAEFGNKW ARIATYLPGR TDNDVKNFWS SRQKRLARIL QNSATPSSSN SKSHKIKKEI 240 PEFQGIHPLE DPKLKALMEE ESSSSKAQLA DMVNPKLHHF GANHSHLQLT PYENDPYTES 300 HLQIHFPQIS QPQQDLIFSP ESQELLARLE DPYFFDVFGS VDAPELSNEV QLPVEQPPLK 360 PETSCRNGGK DGNDKSVNPD AFFDDFPTDM FDHIEPLPSP SDW |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1h8a_C | 2e-27 | 111 | 215 | 24 | 126 | MYB TRANSFORMING PROTEIN |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269|PubMed:15618418, ECO:0000269|PubMed:15694308, ECO:0000269|PubMed:19300502, ECO:0000269|PubMed:21285328, ECO:0000269|PubMed:24876252}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269|PubMed:21441434, ECO:0000269|PubMed:25057814}. |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | KP202871 | 4e-53 | KP202871.1 Jatropha curcas MYB125 mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_006445379.1 | 1e-146 | transcription factor DUO1 | ||||
Refseq | XP_006464457.1 | 1e-146 | transcription factor DUO1 | ||||
Swissprot | A0A178VEK7 | 7e-95 | DUO1_ARATH; Transcription factor DUO1 | ||||
TrEMBL | A0A2H5NP35 | 1e-145 | A0A2H5NP35_CITUN; Uncharacterized protein | ||||
STRING | XP_006464457.1 | 1e-146 | (Citrus sinensis) | ||||
STRING | XP_006445379.1 | 1e-146 | (Citrus clementina) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM6551 | 28 | 42 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G60460.1 | 3e-96 | MYB family protein |
Publications ? help Back to Top | |||
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