PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_21059_f_1

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

MYB_related

Protein Properties

Length: 269aa MW: 30008.7 Da PI: 5.3998

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_21059_f_1	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	41.9	2.3e-13	23	67	3	47
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 +WT+eE+ l++ + ++lG+g+W+ Iar Rt+ q+ s+ qky Neem_21059_f_1 23 PWTEEEHRLFLIGLQKLGKGDWRGIARNYVVSRTPTQVASHAQKY 67 8*******************************************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00717	2.2E-9	20	70	IPR001005	SANT/Myb domain
PROSITE profile	PS51294	16.838	20	72	IPR017930	Myb domain
SuperFamily	SSF46689	6.43E-16	21	73	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	3.1E-18	21	71	IPR006447	Myb domain, plants
Gene3D	G3DSA:1.10.10.60	4.6E-11	22	66	IPR009057	Homeodomain-like
Pfam	PF00249	5.7E-11	23	67	IPR001005	SANT/Myb domain
CDD	cd00167	1.84E-9	23	68	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 269 aa Download sequence Send to blast
MSSHLIAHYP GPPGYEGWYS GVPWTEEEHR LFLIGLQKLG KGDWRGIARN YVVSRTPTQV 60 ASHAQKYFIR QSNASRRKRR SSLFDMVADD MATDTPPVPE EQVLLPSPLA RESDSTNSLP 120 SLNLSLNTEF EPMETVSKEP VKEPEETMTD SNEFTPAVSS FYPAYIPVPY PYWPLNAAAT 180 EEEEKDSRTF HNHQILKPIP ILPKEPVNVD ELVGMSQLSI GESERGLREP SPLSLKLLGE 240 PSRQSAFHAN APVSGSDLRK GKTSPIQAL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription repressor that binds to 5'-TATCCA-3' elements in gene promoters. Contributes to the sugar-repressed transcription of promoters containing SRS or 5'-TATCCA-3' elements. Transcription repressor involved in a cold stress response pathway that confers cold tolerance. Suppresses the DREB1-dependent signaling pathway under prolonged cold stress. DREB1 responds quickly and transiently while MYBS3 responds slowly to cold stress. They may act sequentially and complementarily for adaptation to short- and long-term cold stress (PubMed:20130099). {ECO:0000269\|PubMed:12172034, ECO:0000269\|PubMed:20130099}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by sucrose and gibberellic acid (GA) (PubMed:12172034). Induced by cold stress in roots and shoots. Induced by salt stress in shoots. Down-regulated by abscisic aci (ABA) in shoots (PubMed:20130099). {ECO:0000269\|PubMed:12172034, ECO:0000269\|PubMed:20130099}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006465688.1	1e-149	transcription factor MYBS3
Swissprot	Q7XC57	2e-64	MYBS3_ORYSJ; Transcription factor MYBS3
TrEMBL	A0A067EKQ9	1e-149	A0A067EKQ9_CITSI; Uncharacterized protein (Fragment)
STRING	XP_006465688.1	1e-149	(Citrus sinensis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM9313	27	35

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G16350.1	6e-67	MYB_related family protein

Publications ? help Back to Top
Rice Chromosome 10 Sequencing Consortium In-depth view of structure, activity, and evolution of rice chromosome 10. Science, 2003. 300(5625): p. 1566-9 [PMID:12791992] Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Su CF, et al. A novel MYBS3-dependent pathway confers cold tolerance in rice. Plant Physiol., 2010. 153(1): p. 145-58 [PMID:20130099]