PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_17921_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family NAC
Protein Properties Length: 340aa    MW: 38421.3 Da    PI: 7.7889
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_17921_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM170.26.6e-53231501128
             NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevl 93 
                     l+pGfrFhPtdeelv++yLk+kv +k++++ ++i evdiyk ePwdL +  ++k+++ ewyfFs  dkky +g r nrat +gyWkatgkd+e+ 
  Neem_17921_f_1  23 LAPGFRFHPTDEELVSYYLKRKVCNKPFRF-NAIGEVDIYKNEPWDLAAysRMKTRDLEWYFFSALDKKYGNGARMNRATGRGYWKATGKDREIR 116
                     579*************************99.89**************84348888888************************************* PP

             NAM  94 skkgelvglkktLvfykgrapkgektdWvmheyrl 128
                     + +++l+g+kktLvf+ grap+g++t+Wvmheyrl
  Neem_17921_f_1 117 R-ESQLIGMKKTLVFHCGRAPDGQRTNWVMHEYRL 150
                     9.999****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019413.92E-6220173IPR003441NAC domain
PROSITE profilePS5100558.03623173IPR003441NAC domain
PfamPF023655.0E-2825150IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009555Biological Processpollen development
GO:0010228Biological Processvegetative to reproductive phase transition of meristem
GO:0005730Cellular Componentnucleolus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 340 aa     Download sequence    Send to blast
MGREALALTT PAAKTNTTAT TALAPGFRFH PTDEELVSYY LKRKVCNKPF RFNAIGEVDI  60
YKNEPWDLAA YSRMKTRDLE WYFFSALDKK YGNGARMNRA TGRGYWKATG KDREIRRESQ  120
LIGMKKTLVF HCGRAPDGQR TNWVMHEYRL VEDELDKLRV GQDSYVLCRI FHKSNIGPPN  180
GNRYAPFMEE EWDEGTTTFP GADAGDDVVA GEEACTERNG VETVHVEQDS QSISKEPLNI  240
NELPRDVQND LSMCKRERTE DCPSLCMLNT QAPIPLLQYK RRRQNDSGSN RSNGSENSSG  300
AASPLSLNVL YGNLLHVLVI MLDTPRASQG GRHFIIATIK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A1e-49141758167NO APICAL MERISTEM PROTEIN
1ut4_B1e-49141758167NO APICAL MERISTEM PROTEIN
1ut7_A1e-49141758167NO APICAL MERISTEM PROTEIN
1ut7_B1e-49141758167NO APICAL MERISTEM PROTEIN
3swm_A1e-491417511170NAC domain-containing protein 19
3swm_B1e-491417511170NAC domain-containing protein 19
3swm_C1e-491417511170NAC domain-containing protein 19
3swm_D1e-491417511170NAC domain-containing protein 19
3swp_A1e-491417511170NAC domain-containing protein 19
3swp_B1e-491417511170NAC domain-containing protein 19
3swp_C1e-491417511170NAC domain-containing protein 19
3swp_D1e-491417511170NAC domain-containing protein 19
4dul_A1e-49141758167NAC domain-containing protein 19
4dul_B1e-49141758167NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC051/NAC052 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). {ECO:0000269|PubMed:24045019, ECO:0000269|PubMed:25578968, ECO:0000269|PubMed:26617990}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00612ChIP-seqTransfer from AT3G10490Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006436533.11e-176NAC domain containing protein 50
RefseqXP_006485309.11e-176NAC domain containing protein 50
SwissprotQ9SQX91e-129NAC50_ARATH; NAC domain containing protein 50
TrEMBLA0A067E8M21e-175A0A067E8M2_CITSI; Uncharacterized protein
TrEMBLA0A2H5PQ771e-175A0A2H5PQ77_CITUN; Uncharacterized protein
TrEMBLV4SPQ51e-175V4SPQ5_9ROSI; Uncharacterized protein
STRINGXP_006485309.11e-175(Citrus sinensis)
STRINGXP_006436533.11e-175(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM17802880
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G10480.21e-120NAC domain containing protein 50
Publications ? help Back to Top
  1. Zhang S, et al.
    C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association.
    Cell Discov, 2019.
    [PMID:26617990]