PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_13759_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family bZIP
Protein Properties Length: 754aa    MW: 82123.5 Da    PI: 6.1818
Description bZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_13759_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1bZIP_1452.3e-14243305163
                     XXXXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
          bZIP_1   1 ekelkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklksev 63 
                     e+elkr  r+++NRe+A+ sRqRKk ++eeLe+kv ++ +   +L ++++    e a+l++++
  Neem_13759_f_1 243 EEELKRKARLMRNRESAQLSRQRKKHYVEELEDKVRAMHSTIADLNSKISFFMAENATLRQQL 305
                     799***********************************************9999999999875 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF001702.8E-13243305IPR004827Basic-leucine zipper domain
SMARTSM003384.8E-17243307IPR004827Basic-leucine zipper domain
PROSITE profilePS5021710.151245305IPR004827Basic-leucine zipper domain
SuperFamilySSF579592.06E-12246305No hitNo description
Gene3DG3DSA:1.20.5.1701.7E-17247306No hitNo description
CDDcd147041.49E-21248299No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0042538Biological Processhyperosmotic salinity response
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005783Cellular Componentendoplasmic reticulum
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 754 aa     Download sequence    Send to blast
MADPLLTEAP PPPQHTNPSN DFDSLSIPPL DPLYLASQNN NPSSSSDDLD FVLDENCDFD  60
FNFDDFDNLY FPSENESFFL PSENPTDGQF GSFASDVEGV SCLPRDQEVK VSCTASPESG  120
SSGVSGNRAL LDVDSYLNYS SQNSGNQSSN SNSNSCDREF SGGPASSQGS ENCGSAVSSE  180
TTNAPSPDFD NLVVDQKIKV EEVSKMNIPK RKKEDEEMNN ESRSSKYLRS SLVNENVNDN  240
PSEEELKRKA RLMRNRESAQ LSRQRKKHYV EELEDKVRAM HSTIADLNSK ISFFMAENAT  300
LRQQLSGGSA MPPPGPHMGM YAAPHMAPMP YPWMPCPAPY MVKPQGSQVP LVPIPRLKPQ  360
QTAAPTKPKK SDSSKTKNDG SKNKNDGSKT KKVASVSFLG LLFFVLLFGG LVPFIDVKYG  420
VTDGVSGGYF GSSFYDQHRG RVLTVNGYSN WSHENNGNGF SNGRVDIGNR NKIFCERGIG  480
TTEKESQPSA RSDEFVRLGN ASEPLVASLY VPRNDKLVKI DGNLIIHSVL ASEKAMASQD  540
ASQANSNEET ALAIPDVRGN GARHSHLYRN PAERQRAITS GSADAVKDHM KSTAADGKLQ  600
QWFQEGLAGP LLSSGMCTEV FQFDVSPASA PGAIIPASSV ANITVEHRRN ATHVKKNRRI  660
LDRLPVPLNR ANLNITGEPV DRKSQKNSFQ GNKTASSMVV SVLVDPREAG DVDVDGMITP  720
KSLSRIFVVV LVDSVKYVTY SCVLPRSGVH LVTT
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator involved in salt and osmotic stress responses. Functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression of salt stress response genes (PubMed:17662035). Functions as a stress sensor and transducer in ER stress signaling pathway. ER stress induces proteolysis of BZIP17 by SBT6.1 (S1P) and S2P, and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones, as well as protein involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth (PubMed:20876872). {ECO:0000269|PubMed:17662035, ECO:0000269|PubMed:20876872}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006482041.10.0bZIP transcription factor 17-like
SwissprotO222080.0BZP17_ARATH; bZIP transcription factor 17
TrEMBLA0A067EF100.0A0A067EF10_CITSI; Uncharacterized protein
STRINGXP_006482041.10.0(Citrus sinensis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM88812737
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G40950.11e-169bZIP family protein
Publications ? help Back to Top
  1. Zhou SF, et al.
    Membrane-associated transcription factor peptidase, site-2 protease, antagonizes ABA signaling in Arabidopsis.
    New Phytol., 2015. 208(1): p. 188-97
    [PMID:25919792]
  2. Sagor GH, et al.
    The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 687
    [PMID:26442007]
  3. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  4. Kim JS,Yamaguchi-Shinozaki K,Shinozaki K
    ER-Anchored Transcription Factors bZIP17 and bZIP28 Regulate Root Elongation.
    Plant Physiol., 2018. 176(3): p. 2221-2230
    [PMID:29367234]
  5. Cifuentes-Esquivel N, et al.
    bZIP17 regulates the expression of genes related to seed storage and germination, reducing seed susceptibility to osmotic stress.
    J. Cell. Biochem., 2018. 119(8): p. 6857-6868
    [PMID:29693271]
  6. Guan P, et al.
    SENSITIVE TO SALT1, An Endoplasmic Reticulum-Localized Chaperone, Positively Regulates Salt Resistance.
    Plant Physiol., 2018. 178(3): p. 1390-1405
    [PMID:30287478]