PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_13109_f_2
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family C3H
Protein Properties Length: 749aa    MW: 83329.8 Da    PI: 7.0405
Description C3H family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_13109_f_2genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-CCCH247e-0882106126
                     --S---SGGGGTS--TTTTT-SS-SS CS
         zf-CCCH   1 yktelCrffartGtCkyGdrCkFaHg 26 
                     +kt+lC  f   G C+ G++C+FaHg
  Neem_13109_f_2  82 FKTRLCAKFKH-GSCRNGENCNFAHG 106
                     69*******99.*************9 PP
2zf-CCCH28.32.9e-09151174225
                     -S---SGGGGTS--TTTTT-SS-S CS
         zf-CCCH   2 ktelCrffartGtCkyGdrCkFaH 25 
                     k++lC+ f+ + +C+yGdrC+F H
  Neem_13109_f_2 151 KMKLCKKFYNGEECPYGDRCNFLH 174
                     789*******66************ PP
3zf-CCCH34.53.5e-11227252127
                     --S---SGGGGTS--TTTTT-SS-SSS CS
         zf-CCCH   1 yktelCrffartGtCkyGdrCkFaHgp 27 
                     +kt+lC  + + G+C++G++C+FaHg+
  Neem_13109_f_2 227 WKTKLCTKWTQ-GQCPFGEKCHFAHGQ 252
                     8**********.*************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:4.10.1000.103.3E-1480114IPR000571Zinc finger, CCCH-type
SuperFamilySSF902291.7E-780112IPR000571Zinc finger, CCCH-type
SMARTSM003565.1E-581107IPR000571Zinc finger, CCCH-type
PROSITE profilePS5010315.38581108IPR000571Zinc finger, CCCH-type
PfamPF006428.2E-682106IPR000571Zinc finger, CCCH-type
PROSITE profilePS5010314.333149177IPR000571Zinc finger, CCCH-type
SMARTSM003565.0E-4149176IPR000571Zinc finger, CCCH-type
SuperFamilySSF902294.71E-7149176IPR000571Zinc finger, CCCH-type
Gene3DG3DSA:4.10.1000.103.2E-9151175IPR000571Zinc finger, CCCH-type
PfamPF006428.0E-7151174IPR000571Zinc finger, CCCH-type
Gene3DG3DSA:4.10.1000.101.5E-15222256IPR000571Zinc finger, CCCH-type
SuperFamilySSF902295.23E-9223256IPR000571Zinc finger, CCCH-type
SMARTSM003565.5E-6226252IPR000571Zinc finger, CCCH-type
PROSITE profilePS5010315.939226253IPR000571Zinc finger, CCCH-type
PfamPF006421.1E-8227252IPR000571Zinc finger, CCCH-type
PfamPF092964.4E-10388503IPR015375NADH pyrophosphatase-like, N-terminal
SuperFamilySSF558118.39E-41490679IPR015797NUDIX hydrolase domain-like
Gene3DG3DSA:3.90.79.102.6E-46503668IPR015797NUDIX hydrolase domain-like
PfamPF092971.7E-6507538IPR015376Zinc ribbon, NADH pyrophosphatase
PROSITE profilePS5146218.238539680IPR000086NUDIX hydrolase domain
CDDcd034296.79E-63543727No hitNo description
PfamPF002934.3E-18544668IPR000086NUDIX hydrolase domain
PRINTSPR005021.9E-5570584IPR020476NUDIX hydrolase
PROSITE patternPS008930575596IPR020084NUDIX hydrolase, conserved site
PRINTSPR005021.9E-5584599IPR020476NUDIX hydrolase
Gene3DG3DSA:3.90.79.102.6E-46708727IPR015797NUDIX hydrolase domain-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0016787Molecular Functionhydrolase activity
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 749 aa     Download sequence    Send to blast
MAPELHSYSV GNSDAIGVWP QYPVSNEQQC DRHSQFDQQP PFKRPRNFED NESNSSSYPP  60
MNPRMNPSVN PPVNKGTSSI FFKTRLCAKF KHGSCRNGEN CNFAHGVEDL RQPPPNWQEL  120
VGGGGGGGGG RLEEDRSSGG TWDDDQKIIH KMKLCKKFYN GEECPYGDRC NFLHEDPSKF  180
RDDLGRYRES SAISIGTTGP SVTQGSCSNQ SEVNRPVNNT SIKPVYWKTK LCTKWTQGQC  240
PFGEKCHFAH GQAELQVIGG RTEGEVVNPG LVPVRPQLVP ANESSPTTML PTLNKEGQGK  300
QCLFKFKEYD KRVFGNPRSY RLQAGKLTWL VGCGLWRVDK CNPIRSKTPN STDPFSPTSA  360
LESLKTRLLD NTHQQQQQNS SSSPDFKVLP LRKGRPLAYS CPGETAPLWY LAWISLADCK  420
TLLENSGAEL SEDSLVYLGS RSEDDVVYWA IDVSADSGLV SELGSRQCCF VELRTLMVAT  480
DWADERAMGE LAVAGHARAL LEWHNLSQFC GHCGEKTIPR EAGSRKQCSN ALCNKRIYPR  540
VDPVVIMLVV DRENDRVLLS RQSRFVPRMW SCLAGFIEPG ESLEEAVRRE TWEETGIEVG  600
EVVYHSSQPW PGVTSAHALF SNVGPNSMPC QLMVGFFAYA KSLEINVDKK ELEDAQWHTR  660
EDVKKALTFA EYKKAQRTAA AKVEQICKGV EKGQSLAADF NVESGELAPM FIPGPFAIAH  720
HLISSWVYQD GPGGVQFRKE SFSGSMSNL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6o3p_A1e-4544272799335Peroxisomal NADH pyrophosphatase NUDT12
6o3p_B1e-4544272799335Peroxisomal NADH pyrophosphatase NUDT12
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtMediates the hydrolysis of some nucleoside diphosphate derivatives. Has a high affinity for NADPH compared with that for NADH.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006450979.10.0nudix hydrolase 19, chloroplastic
SwissprotQ94A820.0NUD19_ARATH; Nudix hydrolase 19, chloroplastic
TrEMBLA0A498KEG20.0A0A498KEG2_MALDO; Uncharacterized protein
STRINGXP_006450979.10.0(Citrus clementina)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G19360.16e-88C3H family protein
Publications ? help Back to Top
  1. Klaus SM, et al.
    A nudix enzyme removes pyrophosphate from dihydroneopterin triphosphate in the folate synthesis pathway of bacteria and plants.
    J. Biol. Chem., 2005. 280(7): p. 5274-80
    [PMID:15611104]
  2. Ogawa T,Ueda Y,Yoshimura K,Shigeoka S
    Comprehensive analysis of cytosolic Nudix hydrolases in Arabidopsis thaliana.
    J. Biol. Chem., 2005. 280(26): p. 25277-83
    [PMID:15878881]
  3. Ogawa T, et al.
    Molecular characterization of organelle-type Nudix hydrolases in Arabidopsis.
    Plant Physiol., 2008. 148(3): p. 1412-24
    [PMID:18815383]
  4. Corpas FJ,Aguayo-Trinidad S,Ogawa T,Yoshimura K,Shigeoka S
    Activation of NADPH-recycling systems in leaves and roots of Arabidopsis thaliana under arsenic-induced stress conditions is accelerated by knock-out of Nudix hydrolase 19 (AtNUDX19) gene.
    J. Plant Physiol., 2016. 192: p. 81-9
    [PMID:26878367]
  5. Maruta T, et al.
    Loss-of-function of an Arabidopsis NADPH pyrophosphohydrolase, AtNUDX19, impacts on the pyridine nucleotides status and confers photooxidative stress tolerance.
    Sci Rep, 2016. 6: p. 37432
    [PMID:27874073]