PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_11095_f_2
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family MYB
Protein Properties Length: 554aa    MW: 60816 Da    PI: 8.7545
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_11095_f_2genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding53.74.7e-1759105148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      +g WT+eEde l +av+ + g++Wk+Ia+ ++  R++ qc +rwqk+l
   Neem_11095_f_2  59 KGGWTPEEDETLRNAVATFKGKSWKKIAEFFP-DRSEVQCLHRWQKVL 105
                      688*****************************.************986 PP
2Myb_DNA-binding591.1e-18111157148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      +g+WT+eEd+++ ++v ++G+  W+ Ia+ ++ gR +kqc++rw+++l
   Neem_11095_f_2 111 KGPWTQEEDDKITELVSKYGPTKWSVIAKSLP-GRIGKQCRERWHNHL 157
                      79******************************.*************97 PP
3Myb_DNA-binding569.2e-18163206146
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                      +++WT eE++ l +a++ +G++ W+ Ia+ ++ gRt++++k++w++
   Neem_11095_f_2 163 KDAWTLEEELALMNAHRIHGNK-WAEIAKVLP-GRTDNSIKNHWNS 206
                      679*******************.*********.***********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129415.72554105IPR017930Myb domain
SMARTSM007177.4E-1558107IPR001005SANT/Myb domain
PfamPF002498.3E-1659105IPR001005SANT/Myb domain
SuperFamilySSF466891.94E-1560115IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.6E-2261117IPR009057Homeodomain-like
CDDcd001672.63E-1362105No hitNo description
PROSITE profilePS5129431.365106161IPR017930Myb domain
SuperFamilySSF466891.32E-31108204IPR009057Homeodomain-like
SMARTSM007171.0E-17110159IPR001005SANT/Myb domain
PfamPF002497.4E-18111157IPR001005SANT/Myb domain
CDDcd001671.45E-15113157No hitNo description
Gene3DG3DSA:1.10.10.602.1E-27118164IPR009057Homeodomain-like
PROSITE profilePS5129422.781162212IPR017930Myb domain
SMARTSM007171.3E-16162210IPR001005SANT/Myb domain
PfamPF002496.2E-16163206IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.4E-23165212IPR009057Homeodomain-like
CDDcd001677.82E-13165208No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 554 aa     Download sequence    Send to blast
MAESKIEECC LENKQLTAAS SSSISEGSGS AILKSPGCSS PATTSPTHRR TTGPIRRAKG  60
GWTPEEDETL RNAVATFKGK SWKKIAEFFP DRSEVQCLHR WQKVLNPDLV KGPWTQEEDD  120
KITELVSKYG PTKWSVIAKS LPGRIGKQCR ERWHNHLNPD IKKDAWTLEE ELALMNAHRI  180
HGNKWAEIAK VLPGRTDNSI KNHWNSSLKK KLDFYLATGK LPPVAKNGLQ NGTKDTNQPT  240
GAKRHLVSSN KDSDSTAQTS SGTTDIGKLD EDGGKDLLES SALVQDMAAS SSVRPNESVD  300
SEGAECKPQS PNIDLTCSES MPKLENYAVN QEFVEDRVIE TQTQVGTPTY GSLYYVPPRL  360
KSCIPLDSEP SSTCSVQHEC KSSPITSPIS FFTPPCVKGS GSGAQSPESI LRIAAKTFPN  420
TPSIFRKRRT VEQAQLDANK IGKVDGGTIN DRFHLSGGQE NHENVSEKSR FQEGSLYDSP  480
ACHANDTAEP TGMTFNASPP YRLRSKRTAV FKSVERQLEF TPSKDKRNGN TKSTNLSVNE  540
RAPVGLRTTK KGLT
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h88_C8e-69582125159MYB PROTO-ONCOGENE PROTEIN
1h89_C8e-69582125159MYB PROTO-ONCOGENE PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). {ECO:0000250|UniProtKB:Q94FL9, ECO:0000269|PubMed:26069325}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00482DAPTransfer from AT5G02320Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Slightly induced by ethylene and salicylic acid (SA). {ECO:0000269|PubMed:16463103}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ5673447e-38AJ567344.1 Populus tremula x Populus tremuloides mRNA for MYB transcription factor R3 type (myb gene).
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006429084.10.0transcription factor MYB3R-5
RefseqXP_006429085.10.0transcription factor MYB3R-5
RefseqXP_006480818.10.0transcription factor MYB3R-5
RefseqXP_006480819.10.0transcription factor MYB3R-5
RefseqXP_006480820.10.0transcription factor MYB3R-5
RefseqXP_024037722.10.0transcription factor MYB3R-5
SwissprotQ6R0320.0MB3R5_ARATH; Transcription factor MYB3R-5
TrEMBLA0A4D6V1720.0A0A4D6V172_9ROSI; MYB transcription factor 33
STRINGXP_006480818.10.0(Citrus sinensis)
STRINGXP_006429084.10.0(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM16672887
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G02320.21e-175myb domain protein 3r-5
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  3. Chen P, et al.
    Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage.
    Nat Commun, 2017. 8(1): p. 635
    [PMID:28935922]