PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ahy008246
Organism
Arachis hypogaea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
Family MYB
Protein Properties Length: 276aa    MW: 31865.7 Da    PI: 10.2423
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Ahy#S59555011PU_refUnigeneView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding43.29.1e-142972448
                     S-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  4 WTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     WT+eEd++l + v  +G+++W  Ia+++   +t  qc+ rw++yl
        Ahy008246 29 WTQEEDDILREQVGIHGTENWGIIASKFK-DKTTRQCRRRWFTYL 72
                     ****************************9.*************97 PP
2Myb_DNA-binding47.63.7e-1578123148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      +g W++eEd ll +a k++G++ W+ I++ ++ gRt++ +k+r+ +++
        Ahy008246  78 KGGWSPEEDMLLCEAQKLFGNR-WTEISKVVP-GRTDNAVKNRFSTLR 123
                      688*******************.*********.**********98875 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129415.342172IPR017930Myb domain
SMARTSM007179.6E-112574IPR001005SANT/Myb domain
SuperFamilySSF466895.99E-2726119IPR009057Homeodomain-like
CDDcd001672.39E-112972No hitNo description
PfamPF139217.8E-152989No hitNo description
Gene3DG3DSA:1.10.10.601.4E-202979IPR009057Homeodomain-like
PROSITE profilePS5129421.8173127IPR017930Myb domain
SMARTSM007173.5E-1577125IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.607.9E-2080126IPR009057Homeodomain-like
CDDcd001679.10E-1181122No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 276 aa     Download sequence    Send to blast
MKKQKQKQVV VVANNEESNK KKEHRIVMWT QEEDDILREQ VGIHGTENWG IIASKFKDKT  60
TRQCRRRWFT YLNSDFKKGG WSPEEDMLLC EAQKLFGNRW TEISKVVPGR TDNAVKNRFS  120
TLRKKRAKYE ALAKENHTSY TNSNNKRVIL QHGHVTDSAS ESGVSTKKMR RPHIPVVEER  180
INYGDRLHKQ NGTQISQQPR APFAVLPPNS HNVNNLSDQH DICSLKFNGY GQNKLQGTFL  240
KKDDPRINAL MQQAEFLSSL ALKVDAENMD QSLENX
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A8e-282912510107B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds to DNA in promoters cis-regulatory element 5'-GGCGCGC-3' of cell cycle genes, including cyclins, cyclin-dependent kinases (CDKs), and components of the pre-replication complex (PubMed:20675570, PubMed:24687979). Binds to DNA in promoters cis-regulatory element 5'-AGCCG-3' of auxin regulated genes (e.g. PIN3 and PIN7) (PubMed:26578169). Together with FAMA and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Represses the expression of the mitosis-inducing factors CDKB1-1 and CDKA-1, specifically required for the last guard mother cells (GMC) symmetric divisions in the stomatal pathway (PubMed:20675570, PubMed:24687979). Represses CYCA2-3 in newly formed guard cells (PubMed:21772250). Together with MYB88, regulates stomata spacing by restricting divisions late in the stomatal cell lineage thus limiting the number of GMC divisions (PubMed:16155180). In collaboration with CDKB1-1 and CDKB1-2, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248). Involved in sensing and/or transducing abiotic stress (e.g. drought and salt), probably via the positive regulation of NAC019 (PubMed:21105921). Regulates female reproduction being required for entry into megasporogenesis, probably via the regulation of cell cycle genes (PubMed:22915737). Plays a minor role in lateral roots (LRs) initiation (PubMed:26578065). Involved complementarily in establishing the gravitropic set-point angles of lateral roots by regulating the transcription of PIN3 and PIN7 in gravity-sensing cells of primary and lateral roots (PubMed:26578169). {ECO:0000269|PubMed:16155180, ECO:0000269|PubMed:20675570, ECO:0000269|PubMed:21105921, ECO:0000269|PubMed:21772250, ECO:0000269|PubMed:22915737, ECO:0000269|PubMed:24123248, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24687979, ECO:0000269|PubMed:26578065, ECO:0000269|PubMed:26578169}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015965451.10.0transcription factor MYB124 isoform X1
RefseqXP_015965452.10.0transcription factor MYB124 isoform X1
SwissprotF4IRB41e-101MYB88_ARATH; Transcription factor MYB88
TrEMBLA0A445D9G70.0A0A445D9G7_ARAHY; Uncharacterized protein
TrEMBLA0A445D9H90.0A0A445D9H9_ARAHY; Uncharacterized protein
TrEMBLA0A445D9I90.0A0A445D9I9_ARAHY; Uncharacterized protein
STRINGXP_007157671.11e-149(Phaseolus vulgaris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G02820.11e-104myb domain protein 88
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Yang K, et al.
    Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis.
    J. Exp. Bot., 2014. 65(9): p. 2449-61
    [PMID:24687979]
  4. Yang M
    The FOUR LIPS (FLP) and MYB88 genes conditionally suppress the production of nonstomatal epidermal cells in Arabidopsis cotyledons.
    Am. J. Bot., 2016. 103(9): p. 1559-66
    [PMID:27620181]
  5. Xu Z, et al.
    DGE-seq analysis of MUR3-related Arabidopsis mutants provides insight into how dysfunctional xyloglucan affects cell elongation.
    Plant Sci., 2017. 258: p. 156-169
    [PMID:28330559]
  6. Qu Y, et al.
    Peroxisomal CuAOζ and its product H2O2 regulate the distribution of auxin and IBA-dependent lateral root development in Arabidopsis.
    J. Exp. Bot., 2017. 68(17): p. 4851-4867
    [PMID:28992128]
  7. Xie Y, et al.
    An atypical R2R3 MYB transcription factor increases cold hardiness by CBF-dependent and CBF-independent pathways in apple.
    New Phytol., 2018. 218(1): p. 201-218
    [PMID:29266327]