PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Araha.27670s0001.1.p
Organism
Arabidopsis halleri
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family HSF
Protein Properties Length: 321aa    MW: 36183 Da    PI: 9.0429
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Araha.27670s0001.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind1071.5e-33531442102
                           HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXX CS
          HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgk 90 
                           Fl+k++++++d++l+ +isw  +g sfvv+d+ efa+ +Lp+ Fkh+nf+SFvRQLn+YgF+k+++++         weF+++ F +gk
  Araha.27670s0001.1.p  53 FLSKTFDLVDDPTLDPVISWGLTGASFVVWDPLEFARIILPRNFKHNNFSSFVRQLNTYGFRKIDTDK---------WEFANEAFLRGK 132
                           9****************************************************************999.........************ PP

                           XXXXXXXXXXXX CS
          HSF_DNA-bind  91 kellekikrkks 102
                           k+ll++i+r++s
  Araha.27670s0001.1.p 133 KHLLKNIHRRRS 144
                           *********987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF467852.45E-3348142IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004155.9E-5549142IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene3DG3DSA:1.10.10.102.1E-3550142IPR011991Winged helix-turn-helix DNA-binding domain
PRINTSPR000561.1E-175376IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004471.6E-2953142IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.1E-1791103IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS00434092116IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.1E-17104116IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0010200Biological Processresponse to chitin
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 321 aa     Download sequence    Send to blast
MSPKKDAVSK PTPISVPVST RPGSLYVDTD MGFSGSPLPM PLDILQGNPI PPFLSKTFDL  60
VDDPTLDPVI SWGLTGASFV VWDPLEFARI ILPRNFKHNN FSSFVRQLNT YGFRKIDTDK  120
WEFANEAFLR GKKHLLKNIH RRRSPQSNQT CCSSTSQSQG SPTEVGGEIE KLRKERRALM  180
EEMVELQQQS RGTARHVDTV NQRLKAAEQR QKQLLSFLAK LFQNPGFLER LKNLKGREKG  240
GALGLEKARK KFIKHQQPQD SPTGGEMVKY EADDWERLLI MGFDTTVPSF SNTDVWGNTM  300
DYNDVSEFGF AAETTSDGLP D
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ldu_A2e-245014217120Heat shock factor protein 1
5d5u_B2e-245014226129Heat shock factor protein 1
5d5v_B2e-245014226129Heat shock factor protein 1
5d5v_D2e-245014226129Heat shock factor protein 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress response. Activated by DREB2A under heat stress. {ECO:0000269|PubMed:17999647, ECO:0000269|PubMed:18261981}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAraha.27670s0001.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat stress. {ECO:0000269|PubMed:17999647, ECO:0000269|PubMed:18261981}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1173180.0AK117318.1 Arabidopsis thaliana At5g03720 mRNA for putative heat shock transcription factor, complete cds, clone: RAFL16-88-H09.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002873110.10.0heat stress transcription factor A-3
SwissprotQ8GYY10.0HSFA3_ARATH; Heat stress transcription factor A-3
TrEMBLD7LWT00.0D7LWT0_ARALL; AT-HSFA3
STRINGscaffold_600303.10.0(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM109502529
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03720.10.0heat shock transcription factor A3
Publications ? help Back to Top
  1. Jung HS, et al.
    Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9
    [PMID:23918368]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Nie S,Yue H,Xing D
    A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance.
    Plant Physiol., 2016.
    [PMID:26099269]
  4. Hu Z, et al.
    Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis.
    Plant J., 2015. 84(6): p. 1178-91
    [PMID:26576681]
  5. Song C,Chung WS,Lim CO
    Overexpression of Heat Shock Factor Gene HsfA3 Increases Galactinol Levels and Oxidative Stress Tolerance in Arabidopsis.
    Mol. Cells, 2016. 39(6): p. 477-83
    [PMID:27109422]
  6. Kim GD,Cho YH,Lee BH,Yoo SD
    STABILIZED1 Modulates Pre-mRNA Splicing for Thermotolerance.
    Plant Physiol., 2017. 173(4): p. 2370-2382
    [PMID:28223317]
  7. Song C,Lee J,Kim T,Hong JC,Lim CO
    VOZ1, a transcriptional repressor of DREB2C, mediates heat stress responses in Arabidopsis.
    Planta, 2018. 247(6): p. 1439-1448
    [PMID:29536220]