PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Aradu.5EF4H | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
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Family | C2H2 | ||||||||
Protein Properties | Length: 75aa MW: 9118.91 Da PI: 11.0805 | ||||||||
Description | C2H2 family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | zf-C2H2 | 12.3 | 0.00051 | 31 | 54 | 2 | 23 |
EET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCp..dCgksFsrksnLkrHirtH 23 kCp C+++F+ + Hir+H Aradu.5EF4H 31 KCPwkGCKMTFKWAWARTEHIRVH 54 89********************99 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
SuperFamily | SSF57667 | 2.58E-12 | 16 | 61 | No hit | No description |
Gene3D | G3DSA:3.30.160.60 | 7.2E-12 | 17 | 57 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
SMART | SM00355 | 0.0014 | 30 | 54 | IPR015880 | Zinc finger, C2H2-like |
PROSITE profile | PS50157 | 10.741 | 30 | 59 | IPR007087 | Zinc finger, C2H2 |
PROSITE pattern | PS00028 | 0 | 32 | 54 | IPR007087 | Zinc finger, C2H2 |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0003676 | Molecular Function | nucleic acid binding | ||||
GO:0046872 | Molecular Function | metal ion binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 75 aa Download sequence Send to blast |
MELLPIITVM LGLLRFLSQH RRVHEDDRPL KCPWKGCKMT FKWAWARTEH IRVHTGARPY 60 VLKIRYFESQ KKKKN |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
6a57_A | 4e-27 | 15 | 62 | 61 | 108 | Lysine-specific demethylase REF6 |
6a58_A | 4e-27 | 15 | 62 | 61 | 108 | Lysine-specific demethylase REF6 |
6a59_A | 4e-27 | 15 | 62 | 61 | 108 | Lysine-specific demethylase REF6 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Histone demethylase that demethylates 'Lys-27' (H3K27me) of histone H3. Demethylates both tri- (H3K27me3) and di-methylated (H3K27me2) H3K27me (PubMed:21642989, PubMed:27111035). Demethylates also H3K4me3/2 and H3K36me3/2 in an in vitro assay (PubMed:20711170). Involved in the transcriptional regulation of hundreds of genes regulating developmental patterning and responses to various stimuli (PubMed:18467490). Binds DNA via its four zinc fingers in a sequence-specific manner, 5'-CTCTGYTY-3', to promote the demethylation of H3K27me3 and the regulation of organ boundary formation (PubMed:27111034, PubMed:27111035). Involved in the regulation of flowering time by repressing FLOWERING LOCUS C (FLC) expression (PubMed:15377760). Interacts with the NF-Y complexe to regulate SOC1 (PubMed:25105952). Mediates the recruitment of BRM to its target loci (PubMed:27111034). {ECO:0000269|PubMed:15377760, ECO:0000269|PubMed:18467490, ECO:0000269|PubMed:20711170, ECO:0000269|PubMed:21642989, ECO:0000269|PubMed:25105952, ECO:0000269|PubMed:27111034, ECO:0000269|PubMed:27111035}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Aradu.5EF4H |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | AC235340 | 4e-36 | AC235340.1 Glycine max strain Williams 82 clone GM_WBb0086A04, complete sequence. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_024170153.1 | 1e-27 | lysine-specific demethylase REF6 | ||||
Swissprot | Q9STM3 | 4e-27 | REF6_ARATH; Lysine-specific demethylase REF6 | ||||
TrEMBL | A0A2P6P5A5 | 3e-26 | A0A2P6P5A5_ROSCH; Putative [histone H3]-lysine-36 demethylase | ||||
STRING | XP_004301036.1 | 5e-27 | (Fragaria vesca) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48430.1 | 1e-29 | relative of early flowering 6 |