PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Aqcoe3G254800.1.p | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Ranunculales; Ranunculaceae; Thalictroideae; Aquilegia
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Family | C2H2 | ||||||||
Protein Properties | Length: 83aa MW: 9594.03 Da PI: 10.2802 | ||||||||
Description | C2H2 family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | zf-C2H2 | 12.7 | 0.00039 | 22 | 45 | 2 | 23 |
EET..TTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCp..dCgksFsrksnLkrHirtH 23 kCp C++sF+ + H+r+H Aqcoe3G254800.1.p 22 KCPwkGCTMSFKWAWAKTEHLRKH 45 89*********************9 PP | |||||||
2 | zf-C2H2 | 15.8 | 3.9e-05 | 51 | 77 | 1 | 23 |
EEET..TTTEEESSHHHHHHHHHH..T CS zf-C2H2 1 ykCp..dCgksFsrksnLkrHirt..H 23 y+C+ Cg +F+ s++ rH r+ H Aqcoe3G254800.1.p 51 YQCKikVCGLTFRYVSDFSRHKRRngH 77 9**********************9776 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
SMART | SM00355 | 0.0024 | 21 | 45 | IPR015880 | Zinc finger, C2H2-like |
PROSITE profile | PS50157 | 9.764 | 21 | 50 | IPR007087 | Zinc finger, C2H2 |
Gene3D | G3DSA:3.30.160.60 | 1.9E-7 | 22 | 45 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
PROSITE pattern | PS00028 | 0 | 23 | 45 | IPR007087 | Zinc finger, C2H2 |
SuperFamily | SSF57667 | 1.6E-10 | 31 | 73 | No hit | No description |
Gene3D | G3DSA:3.30.160.60 | 2.0E-8 | 46 | 73 | IPR013087 | Zinc finger C2H2-type/integrase DNA-binding domain |
SMART | SM00355 | 3.4 | 51 | 77 | IPR015880 | Zinc finger, C2H2-like |
PROSITE profile | PS50157 | 10.949 | 51 | 82 | IPR007087 | Zinc finger, C2H2 |
PROSITE pattern | PS00028 | 0 | 53 | 77 | IPR007087 | Zinc finger, C2H2 |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0003676 | Molecular Function | nucleic acid binding | ||||
GO:0046872 | Molecular Function | metal ion binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 83 aa Download sequence Send to blast |
MHPQGMREAV QVTQVCDSSS LKCPWKGCTM SFKWAWAKTE HLRKHTGERS YQCKIKVCGL 60 TFRYVSDFSR HKRRNGHHVD SP* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
6a57_A | 6e-26 | 17 | 79 | 72 | 134 | Lysine-specific demethylase REF6 |
6a58_A | 6e-26 | 17 | 79 | 72 | 134 | Lysine-specific demethylase REF6 |
6a59_A | 6e-26 | 17 | 79 | 72 | 134 | Lysine-specific demethylase REF6 |
6jnl_A | 3e-26 | 17 | 79 | 33 | 95 | Lysine-specific demethylase REF6 |
6jnm_A | 3e-26 | 17 | 79 | 33 | 95 | Lysine-specific demethylase REF6 |
6jnm_B | 3e-26 | 17 | 79 | 33 | 95 | Lysine-specific demethylase REF6 |
6jnn_A | 3e-26 | 17 | 79 | 33 | 95 | Lysine-specific demethylase REF6 |
6jnn_B | 3e-26 | 17 | 79 | 33 | 95 | Lysine-specific demethylase REF6 |
6jnn_G | 3e-26 | 17 | 79 | 33 | 95 | Lysine-specific demethylase REF6 |
6jnn_N | 3e-26 | 17 | 79 | 33 | 95 | Lysine-specific demethylase REF6 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Histone demethylase that demethylates 'Lys-27' (H3K27me) of histone H3. Demethylates both tri- (H3K27me3) and di-methylated (H3K27me2) H3K27me (PubMed:21642989, PubMed:27111035). Demethylates also H3K4me3/2 and H3K36me3/2 in an in vitro assay (PubMed:20711170). Involved in the transcriptional regulation of hundreds of genes regulating developmental patterning and responses to various stimuli (PubMed:18467490). Binds DNA via its four zinc fingers in a sequence-specific manner, 5'-CTCTGYTY-3', to promote the demethylation of H3K27me3 and the regulation of organ boundary formation (PubMed:27111034, PubMed:27111035). Involved in the regulation of flowering time by repressing FLOWERING LOCUS C (FLC) expression (PubMed:15377760). Interacts with the NF-Y complexe to regulate SOC1 (PubMed:25105952). Mediates the recruitment of BRM to its target loci (PubMed:27111034). {ECO:0000269|PubMed:15377760, ECO:0000269|PubMed:18467490, ECO:0000269|PubMed:20711170, ECO:0000269|PubMed:21642989, ECO:0000269|PubMed:25105952, ECO:0000269|PubMed:27111034, ECO:0000269|PubMed:27111035}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_028071343.1 | 5e-31 | probable lysine-specific demethylase ELF6 | ||||
Swissprot | Q9STM3 | 6e-25 | REF6_ARATH; Lysine-specific demethylase REF6 | ||||
TrEMBL | A0A2G5D1B2 | 2e-34 | A0A2G5D1B2_AQUCA; Uncharacterized protein | ||||
STRING | Aquca_030_00119.1 | 4e-35 | (Aquilegia coerulea) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48430.1 | 2e-27 | relative of early flowering 6 |
Link Out ? help Back to Top | |
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Phytozome | Aqcoe3G254800.1.p |